Sfoglia per Autore
Design and synthesis of dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B
2016-01-01 Adornato, Ilenia; Balestri, Francesco; Ottana', Rosaria; Paoli, Paolo; Del Corso, Antonella; Maccari, Rosanna; Lori, Giulia
Identification of novel 5 arylidene-3-phenyl-2 thioxoimidazolidin-4-ones as inhibitors of the chymotrypsin-like activities of the constitutive and immuno-proteasomes
2016-01-01 Adornato, Ilenia; Ettari, Roberta; Maccari, Rosanna; Kaffy, Julia; Ottana', Rosaria; Grasso, Silvana
Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B: In silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents
2017-01-01 Ottana', Rosaria; Paoli, Paolo; Naß, Alexandra; Lori, Giulia; Cardile, Venera; Adornato, Ilenia; Rotondo, Archimede; Graziano, Adriana Carol Eleonora; Wolber, Gerhard; Maccari, Rosanna
EVALUATION OF 4-THIAZOLIDINONE DERIVATIVES AS ALPHA-AMYLASE INHIBITORS
2018-01-01 Adornato, Ilenia; Szabó, Kármen; Mortier, Jérémie; Wolber, Gerhard; Ottana', Rosaria; Maccari, Rosanna
3-ARYL-5-ARYLIDENE-2-THIOXO-4-IMIDAZOLIDINONE DERIVATIVES AS NEW PTP1B ALLOSTERIC INHIBITORS
2018-01-01 Adornato, Ilenia; Paoli, Paolo; Lori, Giulia; Wolber, Gerhard; Naß, Alexandra; Maccari, Rosanna; Ottana', Rosaria
An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications
2018-01-01 Maccari, Rosanna; Del Corso, Antonella; Paoli, Paolo; ADORNATO, ILENIA; Lori, Giulia; Balestri, Francesco; Cappiello, Mario; Naß, Alexandra; Wolber, Gerhard; Ottanà, Rosaria
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors
2018-01-01 Maccari, R.; Ettari, R.; Adornato, I.; Naß, A.; Wolber, G.; Bitto, A.; Mannino, F.; Aliquo', Federica; Bruno, G.; Nicolò, F.; Previti, S.; Grasso, S.; Zappalà, M.; Ottanà, R.
Progettazione, sintesi e valutazione di nuove molecole attive come inibitori di enzimi coinvolti nello sviluppo del diabete mellito e delle sue complicazioni
2018-11-16 Adornato, Ilenia
Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B
2019-01-01 OTTANA', Rosaria; Paoli, Paolo; Lori, Giulia; ADORNATO, ILENIA; PREVITI, SANTO; Naß, Alexandra; Wolber, Gerhard; MACCARI, Rosanna
Searching for alpha-syn inhibitors to fight Parkinson’s disease
2020-01-01 Bucolo, Federica; Vittorio, Serena; Adornato, Ilenia; Gitto, Rosaria; Ventura, Salvador; DE LUCA, Laura
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease
2020-01-01 Vittorio, S.; Adornato, I.; Gitto, R.; Pena-Diaz, S.; Ventura, S.; De Luca, L.
INVESTIGATION ON PYRIDINYL-1,2,4-TRIAZOLE-BASED COMPOUNDS AS -SYN AGGREGATION INHIBITORS FOR TREATING PARKINSON’S DISEASE
2021-01-01 Bucolo, Federica; Vittorio, Serena; Adornato, Ilenia; Gitto, Rosaria; DE LUCA, Laura
In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications-A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B
2021-01-01 Ottana, R.; Paoli, P.; Cappiello, M.; Nguyen, T. N.; Adornato, I.; Del Corso, A.; Genovese, M.; Nesi, I.; Moschini, R.; Nass, A.; Wolber, G.; Maccari, R.
Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects
2021-01-01 Mirabile, S.; Vittorio, S.; Paola Germano, M.; Adornato, I.; Ielo, L.; Rapisarda, A.; Gitto, R.; Pintus, F.; Fais, A.; De Luca, L.
In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules
2021-01-01 Vittorio, S.; Gitto, R.; Adornato, I.; Russo, E.; De Luca, L.
Synthesis and biochemical evaluation of 5-(pyridin-4-yl)-4H-1,2,4-triazol-4-amine-based inhibitors of tyrosinase from Agaricus bisporus
2022-01-01 Gitto, Rosaria; Luca, Laura De; Mirabile, Salvatore; Ricci, Federico; Adornato, Ilenia; Cacciola, Anna; Germanò, Maria Paola
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