Sfoglia per Autore
Synthesis and Biological Characterization of 3-Substituted-1H-indoles as Ligands of GluN2B-Containing N-Methyl-d-aspartate Receptors
2011-01-01 Gitto, Rosaria; DE LUCA, Laura; Ferro, Stefania; Buemi, Mariarosa; Russo, E; De Sarro, G; Costa, LARA TANIA; Ciranna, L; Prezzavento, O; Arena, E; Ronsisvalle, S; Bruno, Giuseppe; Chimirri, Alba
Pituitary adenylate cyclase-activating polypeptide (PACAP) Pac1 receptor activation enhances CA3-CA1 transmission in the rat hippocampus interacting with acethylcholine
2012-01-01 Costa, LARA TANIA; Licata, F.; Li Volsi, G.; Ciranna, L.
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.
2012-01-01 Costa L;Spatuzza M;D'Antoni S;Bonaccorso CM;Trovato C;Musumeci SA;Leopoldo M;Lacivita E;Catania MV;Ciranna L
5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission.
2012-01-01 Costa, LARA TANIA; Trovato, C; Musumeci, Sa; Catania, Mv; Ciranna, L.
Intracellular mechanisms responsible for serotonin-mediated reversal of metabotropic glutamate receptor-mediated long-term depression (mGluR-LTD) in wild-type and Fmr1 KO mouse hippocampus
2013-01-01 Costa, LARA TANIA; C. M., Bonaccorso; S. A., Musumeci; M., Catania; L., Ciranna
The serotonin receptor subtype 7 (5-HT7) modulates hippocampal synaptic transmission and plasticity: a possible novel therapeutic target in cognitive diseases
2014-01-01 Costa, LARA TANIA; Sardone, L. M.; Leopoldo, M.; Lacivita, E.; Ciranna, L.
Potential role of novel 5-HT7 receptor agonists as pharmacological tools in Fragile X Syndrome
2014-01-01 Costa, LARA TANIA; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Puzzo, D; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, L.
Altered mGlu5 receptor surface dynamics are linked to abnormal NMDA receptor function and plasticity in Fragile X Syndrome
2014-01-01 E., Aloisi; J. P., Dupuis; Costa, LARA TANIA; M. G., Haberl; M., Ginger; L., Ladépêche; F., Drago; P. V., Piazza; L., Ciranna; L., Groc; M. V., Catania; A., Frick
Dysfunctions of metabotropic glutamate receptor subtype 5 (mGlu5) receptors in a mouse model of Fragile X syndrome
2014-01-01 M. V., Catania; M., Spatuzza; E., Aloisi; S., D'Antoni; J. P., Dupuis; Costa, LARA TANIA; C. M., Bonaccorso; G., Molinaro; G., Battaglia; S., Musumeci; L., Davidovic; B., Bardoni; L., Ciranna; F., Nicoletti; L., Groc; A., Frick
ACTIVATION OF SEROTONIN TYPE 7 (5-HT7) RECEPTORS AS A NOVEL THERAPEUTIC STRATEGY IN FRAGILE X SYNDROME UNA NUOVA STRATEGIA TERAPEUTICA PER LA SINDROME DEL CROMOSOMA X FRAGILE BASATA SU NUOVE MOLECOLE ATTIVANTI I RECETTORI 5-HT7 PER LA SEROTONINA
2015-01-01 Costa, LARA TANIA; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Puzzo, D.; Gulisano, W.; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, L.
Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome
2015-01-01 Costa, LARA TANIA; Lara Maria, Sardone; Enza, Lacivita; Marcello, Leopoldo; Lucia, Ciranna
Activation of serotonin 5-HT7 receptors rescues hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome through a cyclic AMP-mediated mechanism
2016-01-01 Costa, L.; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, Lucia
Activation of 5-HT7 receptors for serotonin rescues hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome through a cyclic AMP-mediated mechanism involving Cyclin-dependent Kinase 5 and protein synthesis.
2016-01-01 Costa, LARA TANIA; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, L.
Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice
2017-01-01 Aloisi, Elisabetta; Le Corf, Katy; Dupuis, Julien; Zhang, Pei; Ginger, Melanie; Labrousse, Virginie; Spatuzza, Michela; Haberl, Matthias Georg; Costa, Lara Tania; Shigemoto, Ryuichi; Tappe-Theodor, Anke; Drago, Filippo; Piazza, Pier Vincenzo; Mulle, Christophe; Groc, Laurent; Ciranna, Lucia; Catania, Maria Vincenza; Frick, Andreas
A subnanomolar concentration of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine.
2017-01-01 Valeria, Pecoraro; Maria, Sardone Lara; Mariangela, Chisari; Flora, Licata; Volsi Guido, Li; Vincenzo, Perciavalle; Lucia, Ciranna; Costa, Lara Tania
Activation of serotonin 5-HT7 receptors modulates hippocampal synaptic plasticity by activation of adenylate cyclase and rescues learning and behavior in a mouse model of Fragile X Syndrome
2018-01-01 Costa, Lara Tania; Sardone, Lara M.; Bonaccorso, Carmela M.; Spatuzza, Michela; D'Antoni, Simona; Gulisano, Walter; Tropea, Maria R.; Puzzo, Daniela; Leopoldo, Marcello; Lacivita, Enza; Catania, Maria V.; Ciranna, Lucia
Pituitary adenylate cyclase activating polypeptide (PACAP) modulates hippocampal synaptic transmission and plasticity: new therapeutic suggestions for Fragile X Syndrome.
2019-01-01 Ciranna, Lucia; Costa, Lara
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans
2019-01-01 Leggio, G. M.; Torrisi, S. A.; Mastrogiacomo, R.; Mauro, D.; Chisari, M.; Devroye, C.; Scheggia, D.; Nigro, M.; Geraci, F.; Pintori, N.; Giurdanella, G.; Costa, L.; Bucolo, C.; Ferretti, V.; Sortino, M. A.; Ciranna, L.; De Luca, M. A.; Mereu, M.; Managò, F.; Salomone, S.; Drago, F.; Papaleo, F.
Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome
2019-01-01 Maurin, Thomas; Melancia, Francesca; Jarjat, Marielle; Castro, Liliana; Costa, Lara Tania; Delhaye, Sébastien; Khayachi, Anouar; Castagnola, Sara; Mota, Elia; Di Giorgio, Audrey; Servadio, Michela; Drozd, Malgorzata; Poupon, Gwénola; Schiavi, Sara; Sardone, Lara; Azoulay, Stéphane; Ciranna, Lucia; Martin, Stéphane; Vincent, Pierre; Trezza, Viviana; Bardoni, Barbara
Privileged scaffold-based design to identify a novel drug-like 5-HT7 receptor-preferring agonist to target Fragile X syndrome
2020-01-01 Lacivita, Enza; Niso, Mauro; Letizia Stama, Madia; Arzuaga, Anna; Altamura, Concetta; COSTA, Lara Tania; Desaphy, Jean-François; Ragozzino, Michael E.; Ciranna, Lucia; Leopoldo, Marcello
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Synthesis and Biological Characterization of 3-Substituted-1H-indoles as Ligands of GluN2B-Containing N-Methyl-d-aspartate Receptors | 1-gen-2011 | Gitto, Rosaria; DE LUCA, Laura; Ferro, Stefania; Buemi, Mariarosa; Russo, E; De Sarro, G; Costa, LARA TANIA; Ciranna, L; Prezzavento, O; Arena, E; Ronsisvalle, S; Bruno, Giuseppe; Chimirri, Alba | |
| Pituitary adenylate cyclase-activating polypeptide (PACAP) Pac1 receptor activation enhances CA3-CA1 transmission in the rat hippocampus interacting with acethylcholine | 1-gen-2012 | Costa, LARA TANIA; Licata, F.; Li Volsi, G.; Ciranna, L. | |
| Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome. | 1-gen-2012 | Costa L;Spatuzza M;D'Antoni S;Bonaccorso CM;Trovato C;Musumeci SA;Leopoldo M;Lacivita E;Catania MV;Ciranna L | |
| 5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission. | 1-gen-2012 | Costa, LARA TANIA; Trovato, C; Musumeci, Sa; Catania, Mv; Ciranna, L. | |
| Intracellular mechanisms responsible for serotonin-mediated reversal of metabotropic glutamate receptor-mediated long-term depression (mGluR-LTD) in wild-type and Fmr1 KO mouse hippocampus | 1-gen-2013 | Costa, LARA TANIA; C. M., Bonaccorso; S. A., Musumeci; M., Catania; L., Ciranna | |
| The serotonin receptor subtype 7 (5-HT7) modulates hippocampal synaptic transmission and plasticity: a possible novel therapeutic target in cognitive diseases | 1-gen-2014 | Costa, LARA TANIA; Sardone, L. M.; Leopoldo, M.; Lacivita, E.; Ciranna, L. | |
| Potential role of novel 5-HT7 receptor agonists as pharmacological tools in Fragile X Syndrome | 1-gen-2014 | Costa, LARA TANIA; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Puzzo, D; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, L. | |
| Altered mGlu5 receptor surface dynamics are linked to abnormal NMDA receptor function and plasticity in Fragile X Syndrome | 1-gen-2014 | E., Aloisi; J. P., Dupuis; Costa, LARA TANIA; M. G., Haberl; M., Ginger; L., Ladépêche; F., Drago; P. V., Piazza; L., Ciranna; L., Groc; M. V., Catania; A., Frick | |
| Dysfunctions of metabotropic glutamate receptor subtype 5 (mGlu5) receptors in a mouse model of Fragile X syndrome | 1-gen-2014 | M. V., Catania; M., Spatuzza; E., Aloisi; S., D'Antoni; J. P., Dupuis; Costa, LARA TANIA; C. M., Bonaccorso; G., Molinaro; G., Battaglia; S., Musumeci; L., Davidovic; B., Bardoni; L., Ciranna; F., Nicoletti; L., Groc; A., Frick | |
| ACTIVATION OF SEROTONIN TYPE 7 (5-HT7) RECEPTORS AS A NOVEL THERAPEUTIC STRATEGY IN FRAGILE X SYNDROME UNA NUOVA STRATEGIA TERAPEUTICA PER LA SINDROME DEL CROMOSOMA X FRAGILE BASATA SU NUOVE MOLECOLE ATTIVANTI I RECETTORI 5-HT7 PER LA SEROTONINA | 1-gen-2015 | Costa, LARA TANIA; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Puzzo, D.; Gulisano, W.; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, L. | |
| Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome | 1-gen-2015 | Costa, LARA TANIA; Lara Maria, Sardone; Enza, Lacivita; Marcello, Leopoldo; Lucia, Ciranna | |
| Activation of serotonin 5-HT7 receptors rescues hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome through a cyclic AMP-mediated mechanism | 1-gen-2016 | Costa, L.; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, Lucia | |
| Activation of 5-HT7 receptors for serotonin rescues hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome through a cyclic AMP-mediated mechanism involving Cyclin-dependent Kinase 5 and protein synthesis. | 1-gen-2016 | Costa, LARA TANIA; Sardone, L. M.; Spatuzza, M.; Bonaccorso, C. M.; D’Antoni, S.; Leopoldo, M.; Lacivita, E.; Catania, M. V.; Ciranna, L. | |
| Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice | 1-gen-2017 | Aloisi, Elisabetta; Le Corf, Katy; Dupuis, Julien; Zhang, Pei; Ginger, Melanie; Labrousse, Virginie; Spatuzza, Michela; Haberl, Matthias Georg; Costa, Lara Tania; Shigemoto, Ryuichi; Tappe-Theodor, Anke; Drago, Filippo; Piazza, Pier Vincenzo; Mulle, Christophe; Groc, Laurent; Ciranna, Lucia; Catania, Maria Vincenza; Frick, Andreas | |
| A subnanomolar concentration of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine. | 1-gen-2017 | Valeria, Pecoraro; Maria, Sardone Lara; Mariangela, Chisari; Flora, Licata; Volsi Guido, Li; Vincenzo, Perciavalle; Lucia, Ciranna; Costa, Lara Tania | |
| Activation of serotonin 5-HT7 receptors modulates hippocampal synaptic plasticity by activation of adenylate cyclase and rescues learning and behavior in a mouse model of Fragile X Syndrome | 1-gen-2018 | Costa, Lara Tania; Sardone, Lara M.; Bonaccorso, Carmela M.; Spatuzza, Michela; D'Antoni, Simona; Gulisano, Walter; Tropea, Maria R.; Puzzo, Daniela; Leopoldo, Marcello; Lacivita, Enza; Catania, Maria V.; Ciranna, Lucia | |
| Pituitary adenylate cyclase activating polypeptide (PACAP) modulates hippocampal synaptic transmission and plasticity: new therapeutic suggestions for Fragile X Syndrome. | 1-gen-2019 | Ciranna, Lucia; Costa, Lara | |
| The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans | 1-gen-2019 | Leggio, G. M.; Torrisi, S. A.; Mastrogiacomo, R.; Mauro, D.; Chisari, M.; Devroye, C.; Scheggia, D.; Nigro, M.; Geraci, F.; Pintori, N.; Giurdanella, G.; Costa, L.; Bucolo, C.; Ferretti, V.; Sortino, M. A.; Ciranna, L.; De Luca, M. A.; Mereu, M.; Managò, F.; Salomone, S.; Drago, F.; Papaleo, F. | |
| Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome | 1-gen-2019 | Maurin, Thomas; Melancia, Francesca; Jarjat, Marielle; Castro, Liliana; Costa, Lara Tania; Delhaye, Sébastien; Khayachi, Anouar; Castagnola, Sara; Mota, Elia; Di Giorgio, Audrey; Servadio, Michela; Drozd, Malgorzata; Poupon, Gwénola; Schiavi, Sara; Sardone, Lara; Azoulay, Stéphane; Ciranna, Lucia; Martin, Stéphane; Vincent, Pierre; Trezza, Viviana; Bardoni, Barbara | |
| Privileged scaffold-based design to identify a novel drug-like 5-HT7 receptor-preferring agonist to target Fragile X syndrome | 1-gen-2020 | Lacivita, Enza; Niso, Mauro; Letizia Stama, Madia; Arzuaga, Anna; Altamura, Concetta; COSTA, Lara Tania; Desaphy, Jean-François; Ragozzino, Michael E.; Ciranna, Lucia; Leopoldo, Marcello |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile