IELO, LAURA
IELO, LAURA
Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali
Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors
2017-01-01 Ferro, Stefania; DE LUCA, Laura; Germano', Maria Paola; Buemi, Mariarosa; Ielo, Laura; Certo, Giovanna; Kanteev, Margarita; Fishman, Ayelet; Rapisarda, Antonio; Gitto, Rosaria
Chemoselective Homologation-Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into (n+1)-Halomethyl-Alkanes
2020-01-01 Miele, Margherita; Citarella, Andrea; Langer, Thierry; Urban, Ernst; Zehl, Martin; Holzer, Wolfgang; Ielo, Laura; Pace, Vittorio
Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects
2021-01-01 Mirabile, S.; Vittorio, S.; Paola Germano, M.; Adornato, I.; Ielo, L.; Rapisarda, A.; Gitto, R.; Pintus, F.; Fais, A.; De Luca, L.
Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile
2019-01-01 Ielo, L.; Deri, B.; Germano, M. P.; Vittorio, S.; Mirabile, Salvatore; Gitto, R.; Rapisarda, A.; Ronsisvalle, S.; Floris, S.; Pazy, Y.; Fais, A.; Fishman, A.; De Luca, L.
Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors
2022-01-01 Mirabile, Salvatore; Ielo, Laura; Mariapaola, Germanò; Gitto, Rosaria; Pace, Vittorio; De Luca, Laura.
IDENTIFICATION OF NEW TYROSINASE INHIBITORS VIA COMPUTATIONAL STUDIES, SYNTHESIS AND STRUCTURAL CHARACTERIZATION
2018-11-15 Ielo, Laura
Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus
2023-01-01 Mirabile, S.; Ielo, L.; Lombardo, L.; Ricci, F.; Gitto, R.; Germano, M. P.; Pace, V.; De Luca, L.
Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir
2018-01-01 Castoldi, Laura; Ielo, Laura; Hoyos, Pilar; Hernáiz, María J.; De Luca, Laura; Alcántara, Andrés R.; Holzer, Wolfgang; Pace, Vittorio
Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-openingen routeto halohydrins
2021-01-01 Ielo, L.; Miele, M.; Pillari, V.; Senatore, R.; Mirabile, S.; Gitto, R.; Holzer, W.; Alcantara, A. R.; Pace, V.
Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments
2018-01-01 Ferro, Stefania; Deri, Batel; Germanò, Maria Paola; Gitto, Rosaria; Ielo, Laura; Buemi, Maria Rosa; Certo, Giovanna; Vittorio, Serena; Rapisarda, Antonio; Pazy, Yael; Fishman, Ayelet; De Luca, Laura
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors | 1-gen-2017 | Ferro, Stefania; DE LUCA, Laura; Germano', Maria Paola; Buemi, Mariarosa; Ielo, Laura; Certo, Giovanna; Kanteev, Margarita; Fishman, Ayelet; Rapisarda, Antonio; Gitto, Rosaria | |
| Chemoselective Homologation-Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into (n+1)-Halomethyl-Alkanes | 1-gen-2020 | Miele, Margherita; Citarella, Andrea; Langer, Thierry; Urban, Ernst; Zehl, Martin; Holzer, Wolfgang; Ielo, Laura; Pace, Vittorio | |
| Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects | 1-gen-2021 | Mirabile, S.; Vittorio, S.; Paola Germano, M.; Adornato, I.; Ielo, L.; Rapisarda, A.; Gitto, R.; Pintus, F.; Fais, A.; De Luca, L. | |
| Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile | 1-gen-2019 | Ielo, L.; Deri, B.; Germano, M. P.; Vittorio, S.; Mirabile, Salvatore; Gitto, R.; Rapisarda, A.; Ronsisvalle, S.; Floris, S.; Pazy, Y.; Fais, A.; Fishman, A.; De Luca, L. | |
| Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors | 1-gen-2022 | Mirabile, Salvatore; Ielo, Laura; Mariapaola, Germanò; Gitto, Rosaria; Pace, Vittorio; De Luca, Laura. | |
| IDENTIFICATION OF NEW TYROSINASE INHIBITORS VIA COMPUTATIONAL STUDIES, SYNTHESIS AND STRUCTURAL CHARACTERIZATION | 15-nov-2018 | Ielo, Laura | |
| Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus | 1-gen-2023 | Mirabile, S.; Ielo, L.; Lombardo, L.; Ricci, F.; Gitto, R.; Germano, M. P.; Pace, V.; De Luca, L. | |
| Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir | 1-gen-2018 | Castoldi, Laura; Ielo, Laura; Hoyos, Pilar; Hernáiz, María J.; De Luca, Laura; Alcántara, Andrés R.; Holzer, Wolfgang; Pace, Vittorio | |
| Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-openingen routeto halohydrins | 1-gen-2021 | Ielo, L.; Miele, M.; Pillari, V.; Senatore, R.; Mirabile, S.; Gitto, R.; Holzer, W.; Alcantara, A. R.; Pace, V. | |
| Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments | 1-gen-2018 | Ferro, Stefania; Deri, Batel; Germanò, Maria Paola; Gitto, Rosaria; Ielo, Laura; Buemi, Maria Rosa; Certo, Giovanna; Vittorio, Serena; Rapisarda, Antonio; Pazy, Yael; Fishman, Ayelet; De Luca, Laura |