A stereoselective approach towards isoxazolidinyl nucleosides has been designed. The 1,3-dipolar cycloaddition of a C-chiral nitrone with purine and pyrimidine nucleobases produces thymidine and adenine N,O-nucleosides, in enantiomerically pure forms.
A stereoselective approach to isoxazolidinyl nucleosides
IANNAZZO, Daniela;PIPERNO, Anna;ROMEO, Giovanni;ROMEO, Roberto
2001-01-01
Abstract
A stereoselective approach towards isoxazolidinyl nucleosides has been designed. The 1,3-dipolar cycloaddition of a C-chiral nitrone with purine and pyrimidine nucleobases produces thymidine and adenine N,O-nucleosides, in enantiomerically pure forms.File in questo prodotto:
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