A new class of compounds able to block the replication of subgenomic HCV RNA in liver cells is described. 3-Amino-2(5H)furanones 4 may be regarded as diketoacid analogues and were obtained by basic rearrangement of the isoxazolidine nucleus.
3-amino-2(5H) furanones as inhibitors of subgenomic hepatitis C virus RNA replication
IANNAZZO, Daniela;PIPERNO, Anna;ROMEO, Giovanni;ROMEO, Roberto;MASTINO, Antonio;
2008-01-01
Abstract
A new class of compounds able to block the replication of subgenomic HCV RNA in liver cells is described. 3-Amino-2(5H)furanones 4 may be regarded as diketoacid analogues and were obtained by basic rearrangement of the isoxazolidine nucleus.File in questo prodotto:
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