Chicks were treated at 2 weeks of age with 4, 15, 40, 100 and 150 mg/kg of monensin, an ionophore used for its anticoccidial and growth-promoting properties. In the present immunohistochemical study, the expressions and distribution of Na+/K+-ATPase and Ca++-ATPase were studied in myocardium and skeletal muscles (pectoral and quadriceps femoris). We detected an increase of Na+/K+-ATPase immunostaining with prominent staining of the sarcolemma and a slight increase of Ca++-ATPase with prominent staining of the sarcoplasma.

Effects of monensin on Na+/K+-ATPase and Ca++-ATPase activities in chick skeletal muscle and myocardium after subacute treatment

CALO', Margherita;LO CASCIO, Patrizia;LICATA, Patrizia;RICHETTI, Adriana;ZACCONE, Giacomo;NACCARI, Francesco
2002-01-01

Abstract

Chicks were treated at 2 weeks of age with 4, 15, 40, 100 and 150 mg/kg of monensin, an ionophore used for its anticoccidial and growth-promoting properties. In the present immunohistochemical study, the expressions and distribution of Na+/K+-ATPase and Ca++-ATPase were studied in myocardium and skeletal muscles (pectoral and quadriceps femoris). We detected an increase of Na+/K+-ATPase immunostaining with prominent staining of the sarcolemma and a slight increase of Ca++-ATPase with prominent staining of the sarcoplasma.
2002
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/1891105
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