Method to Detect, Monitor and Promote Neural Regeneration and Improvement of Cognitive Function in a Subject Suffering from Neural Injury

Severe traumatic brain (TBl) injuries are often associated with long-term and disabling consequences. Prognosis and chronic treatment planning following severe TBl remain challenging. The discovery of specific brain biomarkers could create new opportunities for more accurate clinical assessments identifying groups that may experience better outcomes when exposed to an intervention. The present invention provides a method of detection of Microtubule associated protein-2 (MAP-2), a marker of dendritic damage, in a biological sample of survivors after TBl and evaluates the recovery of the patient, including an improvement in cognitive abilities and function.