Background: Chronic HCV infection has been associated with a number of extrahepatic manifestations and comorbidities, including diabetes mellitus (DM). Some large observational studies found that treatment response in HIV/HCV co-infected patients was associated with a significant decrease in the risk of DM. Data on the impact of HCV treatment in HIV/HCV co-infected patients with known DM are lacking. We conducted a longitudinal analysis to explore if the HCV treatment with Direct-Acting Antivirals (DAA) had an impact on glucose levels in diabetic individuals.
Impact of HCV treatment with Direct-Acting Antivirals on glucose levels in diabetic HIV/HCV co-infected patients in the ICONA and HepaICONA cohorts
G. Nunnari;G. F. Pellicanò.
2018-01-01
Abstract
Background: Chronic HCV infection has been associated with a number of extrahepatic manifestations and comorbidities, including diabetes mellitus (DM). Some large observational studies found that treatment response in HIV/HCV co-infected patients was associated with a significant decrease in the risk of DM. Data on the impact of HCV treatment in HIV/HCV co-infected patients with known DM are lacking. We conducted a longitudinal analysis to explore if the HCV treatment with Direct-Acting Antivirals (DAA) had an impact on glucose levels in diabetic individuals.File in questo prodotto:
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