Oxidative stress is central to the etiology of Parkinson's disease (PD) and nuclear transcription factor related to NF-E2 (Nrf-2) is involved in neuroprotection against PD pathology, whereby therapeutics designed to enhance antioxidant potential, as dimethyl fumarate (DMF), the most pharmacologically effective molecule among the fumaric acid esters (FAEs), could have clinical value.
Fumaric acid esters attenuate degeneration and promote functional recovery following Parkinson’s disease
Giovanna Casili;Flavia Biundo;Michela Campolo;Salvatore Cuzzocrea;Emanuela Esposito
2016-01-01
Abstract
Oxidative stress is central to the etiology of Parkinson's disease (PD) and nuclear transcription factor related to NF-E2 (Nrf-2) is involved in neuroprotection against PD pathology, whereby therapeutics designed to enhance antioxidant potential, as dimethyl fumarate (DMF), the most pharmacologically effective molecule among the fumaric acid esters (FAEs), could have clinical value.File in questo prodotto:
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