Sirtuins comprise seven family elements (SIRT1-7) involved in various cell signalling pathways comprising cancer inhibition and tumorigenesis. The present study aims to evaluate SIRT2 and SIRT3 gene expression and potential redox reactions in patients with multiple myeloma (MM) at onset and its correlation with disease status, extent and presence of organ damage secondary to myeloma.
SIRT2 and SIRT3 expression correlates with redox imbalance and advanced clinical stage in patients with multiple myeloma
Allegra, Alessandro
Primo
Writing – Original Draft Preparation
;Innao, VanessaResources
;Polito, FrancescaInvestigation
;Oteri, RosariaValidation
;Alibrandi, AngelaFormal Analysis
;Oteri, GiacomoSupervision
;Di Giorgio, Rosa MariaMethodology
;Musolino, CaterinaPenultimo
Project Administration
;Aguennouz, M'hammedUltimo
Conceptualization
2021-01-01
Abstract
Sirtuins comprise seven family elements (SIRT1-7) involved in various cell signalling pathways comprising cancer inhibition and tumorigenesis. The present study aims to evaluate SIRT2 and SIRT3 gene expression and potential redox reactions in patients with multiple myeloma (MM) at onset and its correlation with disease status, extent and presence of organ damage secondary to myeloma.File in questo prodotto:
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Allegra Sirt 2021.pdf
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Allegra_SIRT2 and SIRT3 expression correlates with redox....pdf
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