IRACI, Nunzio

IRACI, Nunzio  

Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali  

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Titolo Data di pubblicazione Autore(i) File
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 1-gen-2007 Logoteta, Patrizia; Iraci, Nunzio; DE LUCA, Laura; Ferro, Stefania; Barreca, Maria Letizia; DE CLERCQ, E.; Chimirri, Alba; Monforte, Anna Maria
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 1-gen-2006 Gitto, Rosaria; DE LUCA, Laura; Barreca, Ml; Iraci, Nunzio; Ferro, Stefania; Arstad, E; Chimirri, A.
A comprehensive structural overview of p38α MAPK in complex with type I inhibitors 1-gen-2015 Astolfi, A.; Iraci, N.; Manfroni, G.; Barreca, M. L.; Cecchetti, V.
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model 1-gen-2012 Shytaj, I. L.; Norelli, S.; Chirullo, B.; Della Corte, A.; Collins, M.; Yalley-Ogunro, J.; Greenhouse, J.; Iraci, N.; Acosta, E. P.; Barreca, M. L.; Lewis, M. G.; Savarino, A.
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 1-gen-2006 DE LUCA, Laura; Barreca, Ml; Ferro, Stefania; Iraci, Nunzio; Chimirri, A.
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 1-gen-2006 DE LUCA, Laura; Barreca, Ml; Ferro, Stefania; Iraci, N; Chimirri, Alba
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 1-gen-2008 DE LUCA, Laura; Barreca, Ml; Ferro, Stefania; Iraci, Nunzio; Debyser, Z; Witvrouw, M; Chimirri, Alba
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 1-gen-2008 DE LUCA, Laura; Barreca, Maria Letizia; Ferro, Stefania; Iraci, Nunzio; Michiels, M; Christ, F; Debyser, Z; Witvrouw, M; Chimirri, Alba
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 1-gen-2009 DE LUCA, Laura; Ferro, Stefania; Agnello, Stefano; Gitto, Rosaria; Monforte, Anna Maria; Iraci, Nunzio; Barreca, Ml; Debyser, Z; Chimirri, Alba
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B palm site i inhibitors case study 1-gen-2014 Barreca, M. L.; Iraci, N.; Manfroni, G.; Gaetani, R.; Guercini, C.; Sabatini, S.; Tabarrini, O.; Cecchetti, V.
Allosteric inhibition of the hepatitis C virus NS5B polymerase: In silico strategies for drug discovery and development 1-gen-2011 Barreca, M. L.; Iraci, N.; Manfroni, G.; Cecchetti, V.
Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study 1-gen-2023 De Gaetano, Federica.; Scala, A.; Celesti, C.; Lambertsen Larsen, K.; Genovese, F.; Bongiorno, C.; Leggio, Loredana.; Iraci, N.; Iraci, Nunzio; Mazzaglia, Antonino; Ventura, C. A.
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 1-gen-2022 DI PIETRO, Maria Letizia; Stagno, Claudio; Efferth, Thomas; Omer, Ejlal A.; D'Angelo, Valeria; Germano', Maria Paola; Cacciola, Anna; DE GAETANO, Federica; Iraci, Nunzio; Micale, Nicola
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 1-gen-2022 Musella, Simona; Carotenuto, Lidia; Iraci, Nunzio; Baroli, Giulia; Ciaglia, Tania; Nappi, Piera; Giovanna Basilicata, Manuela; Salviati, Emanuela; Barrese, Vincenzo; Vestuto, Vincenzo; Pignataro, Giuseppe; Pepe, Giacomo; Sommella, Eduardo; Di Sarno, Veronica; Manfra, Michele; Campiglia, Pietro; Gomez-Monterrey, Isabel; Bertamino, Alessia; Taglialatela, Maurizio; Ostacolo, Carmine; Miceli, Francesco
Bicalutamide Anticancer Activity Enhancement by Formulation of Soluble Inclusion Complexes with Cyclodextrins 1-gen-2022 DE GAETANO, Federica; Maria Chiara Cristiano, ; Donatella, Paolino; Celesti, Consuelo; Iannazzo, Daniela; Venerando, Pistarà; Iraci, Nunzio; Ventura, Cinzia Anna
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 1-gen-2006 Barreca, Maria Letizia; DE LUCA, Laura; Iraci, Nunzio; Chimirri, Alba
Characterization of bicalutamide/cyclodextrin inclusion complexes and anticancer activity evaluation 1-gen-2022 DE GAETANO, Federica; Chiara Cristiano, Maria; Paolino, Donatella; Pistarà, Venerando; Iraci, Nunzio; Ventura, Cinzia Anna
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 1-gen-2005 Iraci, Nunzio; Barreca, Maria Letizia; DE LUCA, Laura; Rao, A; Monforte, Anna Maria; Chimirri, Alba
Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 tat-mediated transcription activity 1-gen-2013 Sancineto, L.; Iraci, N.; Massari, S.; Attanasio, V.; Corazza, G.; Barreca, M. L.; Sabatini, S.; Manfroni, G.; Avanzi, N. R.; Cecchetti, V.; Pannecouque, C.; Marcello, A.; Tabarrini, O.
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 1-gen-2018 Ambrosino, P.; Soldovieri, M. V.; Bast, T.; Turnpenny, P. D.; Uhrig, S.; Biskup, S.; Docker, M.; Fleck, T.; Mosca, I.; Manocchio, L.; Iraci, N.; Taglialatela, M.; Lemke, J. R.