The purpose of this study was to evaluate the impact of physical exercise on the release of cardiac troponins (cTn). Sixteen dogs were evaluated: 8 clinically healthy (group A) and 8 (group B) with valve disease in the asymptomatic stage (class I, New York Heart Association). All dogs, after a complete cardiac evaluation, were forced to exercise on a motorized treadmill at three different speeds: 1.8 km/h (low speed), 3.6 km/h (medium speed), 5.4 km/h (high speed) lasting 6 minutes. Each test was performed on different days. Plasma samples were refrigerated at -20°. cTnI and cTnT were measured just before the running test, after a recovery period of 20 min, and then 2, 4, and 6 h later. cTnI concentrations increased in group A only at the highest speed, while cTnT did not change. These results suggest that exercise may induce myocardial suffering.

IMPACT OF PHYSICAL EXERCISE ON RELEASE OF CARDIAC TROPONINS: EVALUATION IN HEALTHY AND CARDIOPATHIC DOGS

PUGLIESE, Michela;SEMINARA, ANTONIO;DE MAJO, Massimo;LA PIETRA, ANTONINO;NIUTTA, Pietro Paolo
2012-01-01

Abstract

The purpose of this study was to evaluate the impact of physical exercise on the release of cardiac troponins (cTn). Sixteen dogs were evaluated: 8 clinically healthy (group A) and 8 (group B) with valve disease in the asymptomatic stage (class I, New York Heart Association). All dogs, after a complete cardiac evaluation, were forced to exercise on a motorized treadmill at three different speeds: 1.8 km/h (low speed), 3.6 km/h (medium speed), 5.4 km/h (high speed) lasting 6 minutes. Each test was performed on different days. Plasma samples were refrigerated at -20°. cTnI and cTnT were measured just before the running test, after a recovery period of 20 min, and then 2, 4, and 6 h later. cTnI concentrations increased in group A only at the highest speed, while cTnT did not change. These results suggest that exercise may induce myocardial suffering.
2012
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/2431285
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