This paper shows how to exactly define the pathways involved in motor activities through the connection of data from Transcranial Magnetic Stimulation (TMS) and Diffusion Tensor Imaging (DTI) technique computed by using a 3-Tesla Magnetic Resonance Image (MRI) system. The pathways are identified by means of deterministic tractography applied to DTI images acquired with opportune diffusion sequences. By considering the same anatomical MRI with T1-sequence, those DTI images are superimposed to the ones obtained by TMS applied to the cortical areas involved in the motor tasks. Our results indicate that by the superimposing of fiber bundles it is possible to achieve an analysis of anatomical structures not based on brain atlas obtained by normalization, as usually done from medical stuff. The advantage is an analysis with no subjective parameters.

A multimodal approach to trace motor cortical-peripheral pathways based on mixed Transcranial Magnetic Stimulation and Diffusion Tensor Imaging technique

C. Milazzo;G. Anastasi;BRAMANTI, Placido;QUARTARONE, Angelo;GIORDANO, ANNA;AZZERBONI, Bruno;FINOCCHIO, Giovanni;MILARDI, Demetrio
2012

Abstract

This paper shows how to exactly define the pathways involved in motor activities through the connection of data from Transcranial Magnetic Stimulation (TMS) and Diffusion Tensor Imaging (DTI) technique computed by using a 3-Tesla Magnetic Resonance Image (MRI) system. The pathways are identified by means of deterministic tractography applied to DTI images acquired with opportune diffusion sequences. By considering the same anatomical MRI with T1-sequence, those DTI images are superimposed to the ones obtained by TMS applied to the cortical areas involved in the motor tasks. Our results indicate that by the superimposing of fiber bundles it is possible to achieve an analysis of anatomical structures not based on brain atlas obtained by normalization, as usually done from medical stuff. The advantage is an analysis with no subjective parameters.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11570/2434427
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact