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EnglishWe have investigated DMPC: butanol and DPPC: hexanol systems with a high alcohol concentration (two molecules per phospholipid) by means of X-ray diffraction, differential scanning calorimetry and density measurements. A lowering of the main transition temperature for the membrane/alcohol systems has been observed. The phospholipid bilayer/alcohol systems are characterized by a higher density value than the pure membrane as determined by volumetric measurements. The analysis of diffraction patterns has shown the existence of a more packed structure in both systems due to the presence of alcohol. The area of polar head has also been estimated for both samples.
| Titolo: | Effects of medium-chain alcohols on the structure of phospholipid bilayers |
| Autori: | |
| Data di pubblicazione: | 2012 |
| Abstract: | We have investigated DMPC: butanol and DPPC: hexanol systems with a high alcohol concentration (two molecules per phospholipid) by means of X-ray diffraction, differential scanning calorimetry and density measurements. A lowering of the main transition temperature for the membrane/alcohol systems has been observed. The phospholipid bilayer/alcohol systems are characterized by a higher density value than the pure membrane as determined by volumetric measurements. The analysis of diffraction patterns has shown the existence of a more packed structure in both systems due to the presence of alcohol. The area of polar head has also been estimated for both samples. |
| Handle: | http://hdl.handle.net/11570/3108716 |
| ISBN: | 978-1-61499-070-3 |
| Appare nelle tipologie: | 14.b.1 Contributo in volume (Capitolo o Saggio) |
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http://hdl.handle.net/11570/3108716
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