| Nome |
# |
|
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells, file de3e52b2-5c77-762d-e053-3705fe0a30e0
|
30
|
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Exploring the SARS-CoV-2 proteome in the search of potential inhibitors via structure-based pharmacophore modeling/docking approach, file de3e52b4-338f-762d-e053-3705fe0a30e0
|
13
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Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based
virtual screening, file de3e52b0-0e70-762d-e053-3705fe0a30e0
|
9
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|
Development of isoquinolinone derivatives as immunoproteasome inhibitors., file de3e52b5-7009-762d-e053-3705fe0a30e0
|
9
|
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Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs), file de3e52b1-049d-762d-e053-3705fe0a30e0
|
8
|
|
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents., file de3e52b3-bf29-762d-e053-3705fe0a30e0
|
7
|
|
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation, file de3e52af-879b-762d-e053-3705fe0a30e0
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6
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Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases, file de3e52b0-f2a8-762d-e053-3705fe0a30e0
|
6
|
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Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives, file 229e05c7-05c4-4bfa-b080-3299bbd0ffac
|
5
|
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Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma., file de3e52b1-3274-762d-e053-3705fe0a30e0
|
5
|
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Development of peptidomimetic boronates as proteasome inhibitors, file de3e52ae-dd09-762d-e053-3705fe0a30e0
|
4
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NMR conformational analysis in solution of a potent class of cysteine proteases inhibitors, file de3e52af-5e41-762d-e053-3705fe0a30e0
|
4
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Development of novel 1,4-benzodiazepines as antitrypanosomal agents, file de3e52b0-4f13-762d-e053-3705fe0a30e0
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4
|
|
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists, file de3e52b0-ea42-762d-e053-3705fe0a30e0
|
4
|
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Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors, file de3e52b1-329f-762d-e053-3705fe0a30e0
|
4
|
|
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense, file de3e52b2-fb35-762d-e053-3705fe0a30e0
|
4
|
|
null, file de3e52b3-2fc2-762d-e053-3705fe0a30e0
|
4
|
|
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors, file de3e52ae-d95c-762d-e053-3705fe0a30e0
|
3
|
|
Glutamate Binding-Site Ligands of NMDA Receptors, file de3e52ae-dc0a-762d-e053-3705fe0a30e0
|
3
|
|
Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors, file de3e52ae-f362-762d-e053-3705fe0a30e0
|
3
|
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Identification of a new series of amides as non-covalent proteasome inhibitors., file de3e52af-00e9-762d-e053-3705fe0a30e0
|
3
|
|
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors, file de3e52af-6ce7-762d-e053-3705fe0a30e0
|
3
|
|
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents, file de3e52b0-0e74-762d-e053-3705fe0a30e0
|
3
|
|
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives, file de3e52b0-4335-762d-e053-3705fe0a30e0
|
3
|
|
Development of novel amides as non covalent inhibitors of immunoproteasome, file de3e52b0-4f15-762d-e053-3705fe0a30e0
|
3
|
|
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense, file de3e52b5-3a5e-762d-e053-3705fe0a30e0
|
3
|
|
Efficient 3D Database screening for novel HIV-1 IN inhibitors, file de3e52ae-a8ba-762d-e053-3705fe0a30e0
|
2
|
|
Synthesis, chiral resolution and enantiopharmacology of a potent 2,3-benzodiazepine as noncompetitive AMPA receptor antagonist, file de3e52ae-ab36-762d-e053-3705fe0a30e0
|
2
|
|
Synthesis of benzothiazole derivatives and their biological evaluation as anticancer agents, file de3e52ae-da17-762d-e053-3705fe0a30e0
|
2
|
|
Development of peptidomimetic boronates as proteasome inhibitors, file de3e52ae-e3a1-762d-e053-3705fe0a30e0
|
2
|
|
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead, file de3e52af-6766-762d-e053-3705fe0a30e0
|
2
|
|
The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis, file de3e52b0-4b8d-762d-e053-3705fe0a30e0
|
2
|
|
null, file de3e52b3-120f-762d-e053-3705fe0a30e0
|
2
|
|
null, file de3e52b3-6832-762d-e053-3705fe0a30e0
|
2
|
|
Development of novel peptide-based Michael acceptors as antitrypanosomal agents, file de3e52b3-bf1d-762d-e053-3705fe0a30e0
|
2
|
|
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei hodesiense, file de3e52b4-e9e0-762d-e053-3705fe0a30e0
|
2
|
|
Development of peptidyl Michael acceptors for S3 pocket investigation of rhodesain, cysteine protease of Trypanosoma brucei rhodesiense, file de3e52b4-fe49-762d-e053-3705fe0a30e0
|
2
|
|
Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors, file e8071bf3-e9db-404a-a480-69d50523c8ac
|
2
|
|
Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors, file 068c9acf-6260-4dda-9822-5be83c7819bc
|
1
|
|
null, file 302c318b-9421-4263-a5a8-120908362e87
|
1
|
|
Dual inhibition of parasitic targets: a valuable strategy to treat malaria and neglected tropical diseases, file a9f038f6-a252-4c74-b59e-ef3314a20d2f
|
1
|
|
null, file b3eb36b7-2426-4546-a6c2-87378874ad7d
|
1
|
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The inhibition of NS2B/NS3 protease: a new therapeutic opportunity to treat Dengue and Zika virus infection, file d1ee2509-16ca-42a5-aa2f-17c13f2c15b2
|
1
|
|
Novel Peptidomimetics Containing a Vinyl Ester Moiety as Highly Potent and Selective Falcipain-2 Inhibitors, file de3e52ae-adaa-762d-e053-3705fe0a30e0
|
1
|
|
Enantioseparation, absolute configuration determination, and anticonvulsant activity of (+/-)-1-(4-aminophenyl)-7,8-methylenedioxy-1,2,3,5-tetrahydro)-4H-2,3-be nzodiazepin-4-one, file de3e52ae-ae6f-762d-e053-3705fe0a30e0
|
1
|
|
Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain, file de3e52ae-c3d0-762d-e053-3705fe0a30e0
|
1
|
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Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors, file de3e52ae-d95b-762d-e053-3705fe0a30e0
|
1
|
|
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents, file de3e52ae-ec01-762d-e053-3705fe0a30e0
|
1
|
|
Synthesis and Biological Evaluation of Papain-Family Cathepsin L-Like Cysteine Protease Inhibitors Containing a 1,4-Benzodiazepine Scaffold as Antiprotozoal Agents, file de3e52ae-ec03-762d-e053-3705fe0a30e0
|
1
|
|
Synthesis and biological evaluation of new 2-amino-6-(trifluoromethoxy)benzoxazole derivatives, analogues of riluzole., file de3e52ae-f8a8-762d-e053-3705fe0a30e0
|
1
|
|
NMR Characterization and conformational analysis of a potent papain-family cathepsin L-like cysteine protease inhibitor with different behaviour in polar and apolar media, file de3e52af-01cf-762d-e053-3705fe0a30e0
|
1
|
|
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors, file de3e52b0-411e-762d-e053-3705fe0a30e0
|
1
|
|
Development of novel Michael acceptors targeting rhodesain as antitrypanosomal agents, file de3e52b1-019e-762d-e053-3705fe0a30e0
|
1
|
|
null, file de3e52b1-fb2a-762d-e053-3705fe0a30e0
|
1
|
|
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis, file de3e52b2-2518-762d-e053-3705fe0a30e0
|
1
|
|
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs), file de3e52b2-5d46-762d-e053-3705fe0a30e0
|
1
|
|
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense, file de3e52b3-70fb-762d-e053-3705fe0a30e0
|
1
|
|
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome, file de3e52b3-9867-762d-e053-3705fe0a30e0
|
1
|
|
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis, file de3e52b3-986c-762d-e053-3705fe0a30e0
|
1
|
|
Evaluation of curcumin irreversibility, file de3e52b3-ba38-762d-e053-3705fe0a30e0
|
1
|
|
Lead discovery of SARS-CoV-2 main protease inhibitors through covalent docking-based virtual screening, file de3e52b5-049a-762d-e053-3705fe0a30e0
|
1
|
| Totale |
200 |