IRIS
ZAPPALA', Maria
 Distribuzione geografica
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Continente #
NA - Nord America 19.303
EU - Europa 7.100
AS - Asia 6.152
SA - Sud America 2.416
AF - Africa 191
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
AN - Antartide 1
Totale 35.180
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Nazione #
US - Stati Uniti d'America 19.108
SG - Singapore 2.514
BR - Brasile 2.143
IE - Irlanda 1.786
CN - Cina 1.493
SE - Svezia 1.490
UA - Ucraina 870
VN - Vietnam 829
HK - Hong Kong 754
IT - Italia 698
DE - Germania 667
GB - Regno Unito 349
FI - Finlandia 341
RU - Federazione Russa 311
IN - India 133
AT - Austria 130
FR - Francia 128
AR - Argentina 98
CA - Canada 89
PL - Polonia 71
MX - Messico 66
BD - Bangladesh 59
TR - Turchia 58
CZ - Repubblica Ceca 50
ZA - Sudafrica 48
IQ - Iraq 47
BE - Belgio 44
NL - Olanda 44
EC - Ecuador 42
MA - Marocco 41
UZ - Uzbekistan 39
CO - Colombia 33
JP - Giappone 28
ID - Indonesia 25
CL - Cile 23
ES - Italia 23
TN - Tunisia 22
VE - Venezuela 22
CI - Costa d'Avorio 20
PK - Pakistan 20
IR - Iran 19
PE - Perù 16
PY - Paraguay 16
UY - Uruguay 16
DZ - Algeria 15
AE - Emirati Arabi Uniti 14
AZ - Azerbaigian 14
NP - Nepal 14
LT - Lituania 12
LV - Lettonia 12
JM - Giamaica 11
CH - Svizzera 10
EG - Egitto 10
GE - Georgia 10
IL - Israele 10
SN - Senegal 10
JO - Giordania 9
KG - Kirghizistan 9
AL - Albania 8
EU - Europa 8
KE - Kenya 8
KZ - Kazakistan 7
RO - Romania 7
SA - Arabia Saudita 7
BO - Bolivia 6
BY - Bielorussia 6
HN - Honduras 6
KR - Corea 6
PA - Panama 6
DO - Repubblica Dominicana 5
LB - Libano 5
OM - Oman 5
RS - Serbia 5
TT - Trinidad e Tobago 5
AM - Armenia 4
AU - Australia 4
BA - Bosnia-Erzegovina 4
GR - Grecia 4
KW - Kuwait 4
LU - Lussemburgo 4
MY - Malesia 4
BG - Bulgaria 3
CR - Costa Rica 3
DK - Danimarca 3
EE - Estonia 3
MD - Moldavia 3
ML - Mali 3
MU - Mauritius 3
PT - Portogallo 3
SY - Repubblica araba siriana 3
AO - Angola 2
BN - Brunei Darussalam 2
CG - Congo 2
GA - Gabon 2
HU - Ungheria 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AD - Andorra 1
AQ - Antartide 1
Totale 35.155
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Città #
Dallas 10.022
Dublin 1.785
Jacksonville 1.626
Chandler 1.329
Singapore 1.164
Nyköping 999
Ashburn 938
Hong Kong 752
Beijing 687
Dong Ket 554
Princeton 326
Medford 300
Cambridge 283
Dearborn 260
Los Angeles 253
Des Moines 229
Messina 210
Boardman 183
Ann Arbor 169
The Dalles 165
São Paulo 139
Buffalo 136
Vienna 118
Ho Chi Minh City 99
Lancaster 96
New York 93
Munich 88
Redondo Beach 78
Jinan 76
Tianjin 74
San Mateo 73
Milan 71
Hanoi 69
Wilmington 69
Rio de Janeiro 67
Warsaw 66
Moscow 62
Woodbridge 61
Belo Horizonte 59
Nanjing 51
Shenyang 50
Brooklyn 49
Brno 43
Brussels 39
Houston 38
Tashkent 37
Chicago 36
Brasília 35
Hyderabad 34
Haikou 33
Montreal 33
Santa Clara 32
Zhengzhou 31
Curitiba 30
Hebei 30
Porto Alegre 30
Johannesburg 29
Stockholm 29
Pune 28
Amsterdam 27
Helsinki 27
London 27
San Francisco 27
Campinas 26
Frankfurt am Main 26
Seattle 26
Augusta 25
Taizhou 23
Poplar 22
Ningbo 21
Rome 21
Turku 21
Abidjan 20
Aversa 20
Boston 20
Denver 20
Nanchang 20
Fuzhou 19
Norwalk 19
Phoenix 19
Atlanta 18
Baghdad 18
Manaus 18
Salvador 18
St Petersburg 18
Tokyo 18
Chennai 17
Hangzhou 17
Changsha 16
Dhaka 16
Guangzhou 16
Quito 16
Goiânia 15
Mexico City 15
Montevideo 15
Mumbai 15
Nuremberg 15
Orem 15
Campo Grande 14
Istanbul 14
Totale 25.345
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Nome #
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: synthesis and stereochemistry 4.671
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: stereochemistry and anticonvulsant activity 4.644
1-[3,5-bis(trifluoromethyl)phenyl]-1H,3H-thiazolo[3,4- a]benzimidazole 235
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 231
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 223
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 216
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: non-competitive AMPA receptors antagonists 214
1-Adamantanamine derivatives as potential anti-HIV agents 201
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 199
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 164
4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one 153
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni 3a-sostituiti 152
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 150
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 141
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 140
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni isomeri ottenuti da 4-cloro-1,2-fenilendiamina ed acidi 3-acilpropionici 140
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 140
3H-Azirino[1,2-d][1,4]benzodiazepin-4(5H)-ones: synthesis and stereochemistry 138
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 136
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 136
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 131
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 129
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells 126
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 124
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 123
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 121
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 119
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 119
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 119
2,3-Benzodiazepines as potential AMPA receptors antagonists 118
Anti-HIV agents: design and discovery of new potent RT inhibitors 117
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 116
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 115
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 114
Ciclofunzionalizzazione di 1,4- e 1,5-benzodiazepine: sintesi e stereochimica di nuovi sistemi eteropoliciclici ottenuti per reazione con acidi mercaptoacetici 113
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 113
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening 113
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 112
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 111
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives 111
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 111
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 109
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 109
13C NMR study of tetrahydrothiazolo[3,2-d][1,4]benzodiazepin-3(2H)-ones. 107
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 107
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 106
Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. 106
Annelated 1,5-benzothiazepines 106
Design and NMR conformational analysis in solution of β5i-selective inhibitors of immunoproteasome 105
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 105
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain 103
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 102
Evaluation of curcumin irreversibility 102
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 101
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 100
AMINOPYRAZINYL DERIVATIVES - SYNTHESIS AND EVALUATION OF ANTIINFLAMMATORY AND RELATED ACTIVITIES 99
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 99
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 98
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 98
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 98
Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs) 98
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 98
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 97
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 97
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 97
Discovery of novel peptidomimetics containing a benzodiazepine scaffold as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 97
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 97
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 96
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 95
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 95
Falcipain-2 inhibitors 95
An unexpected reaction between 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine and mercaptoacetic acid 95
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 95
High-performance liquid chromatographic determination of new 2,3-benzodiazepines 92
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 92
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 92
ANNELATED 1,5-BENZODIAZEPINES .2. 6 MEMBERED RINGS 92
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 92
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 91
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 91
Development of novel amides as non covalent inhibitors of immunoproteasome 91
The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis 91
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation 91
Synthesis and pharmacological evaluation of 4-aryl-6,7- dimethoxyphthalazines as anticonvulsant agents 90
A physico-chemical study on the interaction between papaverine and natural and modified beta-cyclodextrins 90
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 90
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 89
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 89
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome 89
Composti a presumibile attività antitumorale. IV - Sintesi ed attività antileucemica di N,N'-di-[2-(1,3,4-tiadiazolil)]metilendiamine 1-sostituite 88
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 88
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 88
Efficient 3D Database screening for novel HIV-1 IN inhibitors 88
Reazioni di cross metathesis: applicazione alla sintesi di peptidomimetici potenziali inibitori di falcipaina-2 88
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino,3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent 88
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists 88
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs) 88
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 87
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 87
7-Chloro-1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazole and 1-(2,6-difluorophenyl)-6-methyl-1H,3H- thiazolo[3,4-a]benzimidazole 87
Totale 20.528
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Categoria #
all - tutte 110.016
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 110.016
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.659 0 0 0 0 0 277 20 257 79 249 163 614
2021/20221.983 21 393 31 81 95 5 126 73 35 69 351 703
2022/20235.506 436 434 232 440 443 591 131 323 2.206 20 181 69
2023/20241.223 138 189 87 267 123 122 21 47 6 85 49 89
2024/20255.685 113 76 136 430 234 102 101 1.258 1.525 285 457 968
2025/202614.526 635 3.566 7.543 1.343 1.297 142 0 0 0 0 0 0
Totale 35.767