IRIS
ZAPPALA', Maria
 Distribuzione geografica
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Continente #
NA - Nord America 23.622
EU - Europa 14.986
AS - Asia 7.767
SA - Sud America 2.584
Continente sconosciuto - Info sul continente non disponibili 613
AF - Africa 240
OC - Oceania 10
AN - Antartide 1
Totale 49.823
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Nazione #
US - Stati Uniti d'America 23.203
RU - Federazione Russa 7.481
SG - Singapore 3.168
BR - Brasile 2.234
CN - Cina 2.094
IE - Irlanda 1.787
SE - Svezia 1.497
IT - Italia 923
VN - Vietnam 914
UA - Ucraina 873
HK - Hong Kong 790
DE - Germania 713
FR - Francia 436
GB - Regno Unito 417
FI - Finlandia 341
CA - Canada 190
IN - India 190
AT - Austria 133
AR - Argentina 117
BD - Bangladesh 95
MX - Messico 88
PL - Polonia 83
TR - Turchia 75
IQ - Iraq 70
NL - Olanda 58
ZA - Sudafrica 58
EC - Ecuador 52
CZ - Repubblica Ceca 51
MA - Marocco 51
BE - Belgio 48
UZ - Uzbekistan 48
CO - Colombia 47
JP - Giappone 40
ID - Indonesia 36
PK - Pakistan 36
VE - Venezuela 36
ES - Italia 30
CL - Cile 28
JM - Giamaica 26
TN - Tunisia 26
CI - Costa d'Avorio 22
PY - Paraguay 21
PE - Perù 20
SA - Arabia Saudita 20
IR - Iran 19
TT - Trinidad e Tobago 19
AE - Emirati Arabi Uniti 18
CR - Costa Rica 18
DZ - Algeria 18
UY - Uruguay 18
HN - Honduras 16
NP - Nepal 16
AZ - Azerbaigian 15
MY - Malesia 15
LT - Lituania 14
GE - Georgia 13
KE - Kenya 13
IL - Israele 12
JO - Giordania 12
LV - Lettonia 12
EG - Egitto 11
SV - El Salvador 11
BO - Bolivia 10
CH - Svizzera 10
KG - Kirghizistan 10
SN - Senegal 10
AL - Albania 9
NI - Nicaragua 9
EU - Europa 8
KZ - Kazakistan 8
PR - Porto Rico 8
RO - Romania 8
AU - Australia 7
GT - Guatemala 7
LB - Libano 7
PA - Panama 7
BY - Bielorussia 6
DK - Danimarca 6
DO - Repubblica Dominicana 6
EE - Estonia 6
GP - Guadalupe 6
GR - Grecia 6
KR - Corea 6
BA - Bosnia-Erzegovina 5
CW - ???statistics.table.value.countryCode.CW??? 5
KW - Kuwait 5
OM - Oman 5
RS - Serbia 5
SC - Seychelles 5
SY - Repubblica araba siriana 5
AM - Armenia 4
ET - Etiopia 4
HU - Ungheria 4
LU - Lussemburgo 4
ML - Mali 4
MU - Mauritius 4
PH - Filippine 4
PT - Portogallo 4
TH - Thailandia 4
AO - Angola 3
Totale 49.170
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Città #
Dallas 10.053
Moscow 2.313
Dublin 1.786
Ashburn 1.759
Singapore 1.697
Jacksonville 1.638
Chandler 1.329
Nyköping 999
Hong Kong 787
San Jose 758
Beijing 718
Council Bluffs 616
Dong Ket 554
Princeton 326
The Dalles 301
Medford 300
Los Angeles 287
Cambridge 283
Lauterbourg 271
Dearborn 260
Des Moines 232
Messina 221
Boardman 191
Ann Arbor 169
São Paulo 146
Buffalo 142
New York 136
Vienna 120
Ho Chi Minh City 118
Tianjin 114
Lancaster 98
Hanoi 89
Munich 88
Milan 87
Santa Clara 84
Guangzhou 78
Redondo Beach 78
Jinan 76
Warsaw 76
Wilmington 74
San Mateo 73
Rio de Janeiro 70
Columbus 65
Montreal 64
Brooklyn 62
Woodbridge 61
Belo Horizonte 60
Houston 59
Phoenix 57
Chicago 55
Frankfurt am Main 53
Nanjing 51
Orem 50
Rome 50
Shenyang 50
Tashkent 46
Brno 43
Amsterdam 40
Brussels 40
Brasília 37
San Francisco 37
Atlanta 36
Hyderabad 36
Shanghai 36
Stockholm 35
Curitiba 33
Haikou 33
Johannesburg 33
Porto Alegre 33
Shenzhen 33
Zhengzhou 32
Seattle 31
Hebei 30
London 30
Tokyo 30
Baghdad 28
Chennai 28
Denver 28
Pune 28
Campinas 27
Helsinki 27
Augusta 26
Poplar 26
Boston 23
Mexico City 23
Mumbai 23
Taizhou 23
Abidjan 22
Nuremberg 22
Ningbo 21
Turku 21
Aversa 20
Dhaka 20
Nanchang 20
Norwalk 20
Fuzhou 19
Kingston 19
Manchester 19
Hangzhou 18
Manaus 18
Totale 31.605
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Nome #
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: synthesis and stereochemistry 4.746
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: stereochemistry and anticonvulsant activity 4.728
1-[3,5-bis(trifluoromethyl)phenyl]-1H,3H-thiazolo[3,4- a]benzimidazole 323
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 314
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 306
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 285
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: non-competitive AMPA receptors antagonists 282
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 271
1-Adamantanamine derivatives as potential anti-HIV agents 262
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 259
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 227
4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one 225
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 214
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 213
Development of novel Michael acceptors targeting rhodesain as antitrypanosomal agents 208
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 205
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni 3a-sostituiti 204
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 199
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 199
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 198
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni isomeri ottenuti da 4-cloro-1,2-fenilendiamina ed acidi 3-acilpropionici 193
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 193
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 190
3H-Azirino[1,2-d][1,4]benzodiazepin-4(5H)-ones: synthesis and stereochemistry 190
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 188
Anti-HIV agents: design and discovery of new potent RT inhibitors 185
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 180
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 180
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells 179
Drug combination studies of isoquinolinone AM12 with curcumin or quercetin: a new combination strategy to synergistically inhibit 20S proteasome 178
2,3-Benzodiazepines as potential AMPA receptors antagonists 177
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 176
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain 174
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 174
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 174
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 174
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 173
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 172
13C NMR study of tetrahydrothiazolo[3,2-d][1,4]benzodiazepin-3(2H)-ones. 172
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 171
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 169
Design and NMR conformational analysis in solution of β5i-selective inhibitors of immunoproteasome 168
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 168
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening 168
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 167
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 165
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 162
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 161
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 161
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 161
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 160
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives 160
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 160
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 160
Development of novel amides as non covalent inhibitors of immunoproteasome 159
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 157
Evaluation of curcumin irreversibility 157
ANNELATED 1,5-BENZODIAZEPINES .2. 6 MEMBERED RINGS 156
Falcipain-2 inhibitors 156
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 156
Annelated 1,5-benzothiazepines 156
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 156
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 155
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 155
AMINOPYRAZINYL DERIVATIVES - SYNTHESIS AND EVALUATION OF ANTIINFLAMMATORY AND RELATED ACTIVITIES 155
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 154
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 153
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 152
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 151
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 150
Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. 150
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 150
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 149
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 149
7-Chloro-1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazole and 1-(2,6-difluorophenyl)-6-methyl-1H,3H- thiazolo[3,4-a]benzimidazole 148
Development of novel 1,4-benzodiazepines as antitrypanosomal agents 148
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome 148
Discovery of novel peptidomimetics containing a benzodiazepine scaffold as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 148
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 146
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei hodesiense 144
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 143
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 143
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 143
A physico-chemical study on the interaction between papaverine and natural and modified beta-cyclodextrins 143
Ciclofunzionalizzazione di 1,4- e 1,5-benzodiazepine: sintesi e stereochimica di nuovi sistemi eteropoliciclici ottenuti per reazione con acidi mercaptoacetici 142
Efficient 3D Database screening for novel HIV-1 IN inhibitors 142
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis 142
Glutamate Binding-Site Ligands of NMDA Receptors 141
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists 140
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 140
Anti-HIV agents .4. Synthesis and in vitro anti-HIV activity of novel 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazoles 139
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 139
Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives 138
An unexpected reaction between 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine and mercaptoacetic acid 138
2,3-Benzodiazepine-based noncompetitive AMPAR antagonists: design, synthesis, binding affinity and mechanism of inhibition of the GluR2Qflip homomeric receptor channel 138
Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors 137
Synthesis and structural features of new cyclofunctionalized benzimidazoles 137
Cross-metathesis reactions applications to the synthesis of peptidomimetics as potent falcipain-2 inhibitors 137
Development of novel peptide-based Michael acceptors as antitrypanosomal agents 137
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 136
Totale 26.504
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Categoria #
all - tutte 145.957
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 145.957
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.457 0 0 0 0 95 5 126 73 35 69 351 703
2022/20235.506 436 434 232 440 443 591 131 323 2.206 20 181 69
2023/20241.223 138 189 87 267 123 122 21 47 6 85 49 89
2024/20255.685 113 76 136 430 234 102 101 1.258 1.525 285 457 968
2025/202625.546 635 3.566 7.543 1.343 1.301 4.004 2.135 1.999 1.925 588 258 249
2026/20273.036 291 721 914 1.093 17 0 0 0 0 0 0 0
Totale 49.823