IRIS
ZAPPALA', Maria
 Distribuzione geografica
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Continente #
NA - Nord America 21.720
EU - Europa 14.791
AS - Asia 7.751
SA - Sud America 2.579
Continente sconosciuto - Info sul continente non disponibili 608
AF - Africa 235
OC - Oceania 10
AN - Antartide 1
Totale 47.695
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Nazione #
US - Stati Uniti d'America 21.441
RU - Federazione Russa 7.474
SG - Singapore 3.164
BR - Brasile 2.231
CN - Cina 2.090
IE - Irlanda 1.787
SE - Svezia 1.496
VN - Vietnam 914
UA - Ucraina 871
HK - Hong Kong 788
IT - Italia 777
DE - Germania 711
FR - Francia 430
GB - Regno Unito 394
FI - Finlandia 341
IN - India 190
AT - Austria 133
CA - Canada 121
AR - Argentina 117
BD - Bangladesh 93
MX - Messico 86
PL - Polonia 82
TR - Turchia 73
IQ - Iraq 70
NL - Olanda 58
ZA - Sudafrica 58
EC - Ecuador 52
CZ - Repubblica Ceca 51
MA - Marocco 51
UZ - Uzbekistan 48
BE - Belgio 47
CO - Colombia 47
JP - Giappone 40
ID - Indonesia 36
PK - Pakistan 35
VE - Venezuela 35
ES - Italia 30
CL - Cile 27
TN - Tunisia 26
CI - Costa d'Avorio 22
PY - Paraguay 21
PE - Perù 20
SA - Arabia Saudita 20
IR - Iran 19
JM - Giamaica 19
AE - Emirati Arabi Uniti 18
UY - Uruguay 18
DZ - Algeria 17
NP - Nepal 16
AZ - Azerbaigian 15
MY - Malesia 15
GE - Georgia 13
KE - Kenya 13
LT - Lituania 13
IL - Israele 12
JO - Giordania 12
LV - Lettonia 12
EG - Egitto 11
BO - Bolivia 10
CH - Svizzera 10
HN - Honduras 10
KG - Kirghizistan 10
SN - Senegal 10
AL - Albania 9
CR - Costa Rica 9
EU - Europa 8
KZ - Kazakistan 8
RO - Romania 8
AU - Australia 7
LB - Libano 7
PA - Panama 7
BY - Bielorussia 6
DK - Danimarca 6
KR - Corea 6
TT - Trinidad e Tobago 6
BA - Bosnia-Erzegovina 5
DO - Repubblica Dominicana 5
GR - Grecia 5
KW - Kuwait 5
OM - Oman 5
RS - Serbia 5
SY - Repubblica araba siriana 5
AM - Armenia 4
ET - Etiopia 4
LU - Lussemburgo 4
ML - Mali 4
MU - Mauritius 4
NI - Nicaragua 4
PH - Filippine 4
PT - Portogallo 4
TH - Thailandia 4
AO - Angola 3
BG - Bulgaria 3
EE - Estonia 3
GA - Gabon 3
GT - Guatemala 3
HU - Ungheria 3
MD - Moldavia 3
SV - El Salvador 3
BN - Brunei Darussalam 2
Totale 47.055
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Città #
Dallas 10.040
Moscow 2.313
Dublin 1.786
Singapore 1.695
Jacksonville 1.634
Ashburn 1.357
Chandler 1.329
Nyköping 999
Hong Kong 785
Beijing 717
Dong Ket 554
San Jose 505
Council Bluffs 501
Princeton 326
The Dalles 301
Medford 300
Cambridge 283
Los Angeles 274
Lauterbourg 271
Dearborn 260
Des Moines 231
Messina 221
Boardman 183
Ann Arbor 169
São Paulo 146
Buffalo 137
New York 126
Vienna 120
Ho Chi Minh City 118
Tianjin 114
Lancaster 96
Hanoi 89
Munich 88
Guangzhou 78
Redondo Beach 78
Jinan 76
Milan 76
Warsaw 76
San Mateo 73
Rio de Janeiro 70
Wilmington 69
Santa Clara 68
Columbus 64
Woodbridge 61
Belo Horizonte 60
Brooklyn 53
Frankfurt am Main 53
Nanjing 51
Shenyang 50
Orem 48
Chicago 47
Houston 46
Tashkent 46
Montreal 45
Brno 43
Amsterdam 40
Brussels 40
Brasília 36
Hyderabad 36
Shanghai 36
Stockholm 35
Curitiba 33
Haikou 33
Johannesburg 33
Porto Alegre 33
Shenzhen 33
San Francisco 32
Zhengzhou 32
Hebei 30
London 30
Tokyo 30
Baghdad 28
Chennai 28
Pune 28
Rome 28
Campinas 27
Helsinki 27
Phoenix 27
Seattle 27
Atlanta 26
Denver 26
Poplar 26
Augusta 25
Mumbai 23
Taizhou 23
Abidjan 22
Boston 22
Mexico City 22
Nuremberg 22
Ningbo 21
Turku 21
Aversa 20
Dhaka 20
Nanchang 20
Fuzhou 19
Manchester 19
Norwalk 19
Hangzhou 18
Manaus 18
Quito 18
Totale 30.611
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Nome #
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: synthesis and stereochemistry 4.735
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: stereochemistry and anticonvulsant activity 4.715
1-[3,5-bis(trifluoromethyl)phenyl]-1H,3H-thiazolo[3,4- a]benzimidazole 306
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 302
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 295
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 276
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: non-competitive AMPA receptors antagonists 275
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 261
1-Adamantanamine derivatives as potential anti-HIV agents 254
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 241
4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one 213
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 212
Development of novel Michael acceptors targeting rhodesain as antitrypanosomal agents 207
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 205
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 201
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni 3a-sostituiti 199
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 194
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 193
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 192
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 191
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 189
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni isomeri ottenuti da 4-cloro-1,2-fenilendiamina ed acidi 3-acilpropionici 188
3H-Azirino[1,2-d][1,4]benzodiazepin-4(5H)-ones: synthesis and stereochemistry 187
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 184
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 179
Anti-HIV agents: design and discovery of new potent RT inhibitors 175
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 175
2,3-Benzodiazepines as potential AMPA receptors antagonists 173
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 173
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells 172
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 169
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 169
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 169
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 166
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 164
13C NMR study of tetrahydrothiazolo[3,2-d][1,4]benzodiazepin-3(2H)-ones. 164
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 163
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 163
Design and NMR conformational analysis in solution of β5i-selective inhibitors of immunoproteasome 162
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 161
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 161
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 160
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 159
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening 159
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 158
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain 157
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 156
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 156
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 155
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 155
Development of novel amides as non covalent inhibitors of immunoproteasome 155
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 154
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 154
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 152
Annelated 1,5-benzothiazepines 152
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 151
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 150
ANNELATED 1,5-BENZODIAZEPINES .2. 6 MEMBERED RINGS 149
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives 149
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 149
AMINOPYRAZINYL DERIVATIVES - SYNTHESIS AND EVALUATION OF ANTIINFLAMMATORY AND RELATED ACTIVITIES 148
Falcipain-2 inhibitors 148
Evaluation of curcumin irreversibility 148
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 147
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 147
Drug combination studies of isoquinolinone AM12 with curcumin or quercetin: a new combination strategy to synergistically inhibit 20S proteasome 146
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 146
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 145
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 145
Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. 144
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 143
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 143
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome 142
Discovery of novel peptidomimetics containing a benzodiazepine scaffold as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 142
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 141
Development of novel 1,4-benzodiazepines as antitrypanosomal agents 141
Ciclofunzionalizzazione di 1,4- e 1,5-benzodiazepine: sintesi e stereochimica di nuovi sistemi eteropoliciclici ottenuti per reazione con acidi mercaptoacetici 140
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 139
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 139
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 139
7-Chloro-1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazole and 1-(2,6-difluorophenyl)-6-methyl-1H,3H- thiazolo[3,4-a]benzimidazole 138
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei hodesiense 138
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 137
Efficient 3D Database screening for novel HIV-1 IN inhibitors 137
A physico-chemical study on the interaction between papaverine and natural and modified beta-cyclodextrins 136
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 136
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 135
An unexpected reaction between 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine and mercaptoacetic acid 135
Cross-metathesis reactions applications to the synthesis of peptidomimetics as potent falcipain-2 inhibitors 134
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 134
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis 133
Anti-HIV agents .4. Synthesis and in vitro anti-HIV activity of novel 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazoles 132
2,3-Benzodiazepine-based noncompetitive AMPAR antagonists: design, synthesis, binding affinity and mechanism of inhibition of the GluR2Qflip homomeric receptor channel 132
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists 131
Synthesis and structural features of new cyclofunctionalized benzimidazoles 130
Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives 129
Development of novel peptide-based Michael acceptors as antitrypanosomal agents 129
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 128
Anti-HIV agents II. Synthesis and in vitro anti-HIV activity of novel 1H,3H-thiazolo[3,4-a]benzimidazoles. 127
Anti-HIV agents. V. Synthesis, structure and in vitro anti-HIV activity of novel 1H,3H-naphtho[2 ',3 ': 4,5]imidazo[1,2- c]thiazoles 127
Totale 25.734
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Categoria #
all - tutte 137.316
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 137.316
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.962 0 393 31 81 95 5 126 73 35 69 351 703
2022/20235.506 436 434 232 440 443 591 131 323 2.206 20 181 69
2023/20241.223 138 189 87 267 123 122 21 47 6 85 49 89
2024/20255.685 113 76 136 430 234 102 101 1.258 1.525 285 457 968
2025/202625.546 635 3.566 7.543 1.343 1.301 4.004 2.135 1.999 1.925 588 258 249
2026/2027908 291 617 0 0 0 0 0 0 0 0 0 0
Totale 47.695