IRIS
ZAPPALA', Maria
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 7.155
EU - Europa 6.123
AS - Asia 1.617
AF - Africa 14
SA - Sud America 11
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 5
Totale 14.934
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 7.123
IE - Irlanda 1.784
SE - Svezia 1.466
CN - Cina 930
UA - Ucraina 836
IT - Italia 572
VN - Vietnam 556
DE - Germania 537
FI - Finlandia 292
GB - Regno Unito 274
AT - Austria 113
IN - India 88
FR - Francia 82
BE - Belgio 41
RU - Federazione Russa 41
PL - Polonia 32
CA - Canada 28
IR - Iran 18
NL - Olanda 14
EU - Europa 8
LV - Lettonia 7
CZ - Repubblica Ceca 6
CH - Svizzera 5
CL - Cile 5
SG - Singapore 5
AU - Australia 4
KR - Corea 4
RO - Romania 4
ZA - Sudafrica 4
DZ - Algeria 3
LU - Lussemburgo 3
PE - Perù 3
SA - Arabia Saudita 3
BD - Bangladesh 2
BG - Bulgaria 2
BR - Brasile 2
EE - Estonia 2
EG - Egitto 2
ES - Italia 2
HK - Hong Kong 2
MX - Messico 2
NG - Nigeria 2
PA - Panama 2
PT - Portogallo 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
DK - Danimarca 1
EC - Ecuador 1
GR - Grecia 1
HR - Croazia 1
IL - Israele 1
IQ - Iraq 1
IS - Islanda 1
JP - Giappone 1
KZ - Kazakistan 1
MA - Marocco 1
MD - Moldavia 1
MU - Mauritius 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
SC - Seychelles 1
TH - Thailandia 1
Totale 14.934
Salva come PNG Salva come JPEG
Città #
Dublin 1.783
Jacksonville 1.624
Chandler 1.333
Nyköping 1.003
Dong Ket 554
Beijing 414
Ashburn 393
Princeton 326
Medford 300
Cambridge 283
Dearborn 260
Des Moines 229
Boardman 182
Messina 180
Ann Arbor 169
Vienna 113
Lancaster 96
Jinan 76
San Mateo 73
Milan 70
Wilmington 69
Woodbridge 61
Nanjing 51
Shenyang 50
Brussels 36
Hyderabad 34
Haikou 33
Zhengzhou 31
Hebei 30
Warsaw 30
Tianjin 29
Houston 28
Pune 28
Augusta 23
Taizhou 23
Ningbo 21
Nanchang 20
Fuzhou 19
New York 19
Norwalk 19
Los Angeles 18
Seattle 18
Changsha 15
Hangzhou 15
Guangzhou 14
London 14
Ardabil 13
Taiyuan 13
Montpellier 12
Catania 11
Jiaxing 11
Montréal 11
Washington 11
Helsinki 10
Edinburgh 9
Mcallen 9
Monmouth Junction 9
Ottawa 9
Rome 9
Saint Petersburg 9
Brooklyn 8
Nuremberg 8
West Jordan 8
Auburn Hills 7
Francofonte 7
Leawood 7
Siderno 7
Berlin 6
Borghetto Santo Spirito 6
Clearwater 6
Francavilla di Sicilia 6
Mumbai 6
Munich 6
Riva 6
Bari 5
Caltagirone 5
Hanover 5
Hefei 5
Novokuznetsk 5
Riposto 5
Southampton 5
Amsterdam 4
Bremen 4
Brno 4
Nanning 4
Palermo 4
Santa Clara 4
Singapore 4
Trecastagni 4
Bangalore 3
Boston 3
Cape Town 3
Chicago 3
Dallas 3
Fontaniva 3
Kunming 3
Lanzhou 3
Las Vegas 3
Lentini 3
Leonforte 3
Totale 10.549
Salva come PNG Salva come JPEG
Nome #
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: synthesis and stereochemistry 190
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: stereochemistry and anticonvulsant activity 190
1-[3,5-bis(trifluoromethyl)phenyl]-1H,3H-thiazolo[3,4- a]benzimidazole 150
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 144
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 141
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 139
1-Adamantanamine derivatives as potential anti-HIV agents 133
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 130
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: non-competitive AMPA receptors antagonists 127
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni 3a-sostituiti 92
Ciclofunzionalizzazione di 1,4- e 1,5-benzodiazepine: sintesi e stereochimica di nuovi sistemi eteropoliciclici ottenuti per reazione con acidi mercaptoacetici 91
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 89
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells 86
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 85
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 79
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni isomeri ottenuti da 4-cloro-1,2-fenilendiamina ed acidi 3-acilpropionici 77
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 77
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 76
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 75
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 74
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 72
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 72
4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one 72
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 71
Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs) 70
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 70
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 69
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 68
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 68
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 67
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 67
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 67
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 67
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 67
Anti-HIV agents: design and discovery of new potent RT inhibitors 66
3H-Azirino[1,2-d][1,4]benzodiazepin-4(5H)-ones: synthesis and stereochemistry 66
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 66
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives 65
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 63
Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. 63
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 62
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 62
Annelated 1,5-benzothiazepines 62
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 61
High-performance liquid chromatographic determination of new 2,3-benzodiazepines 61
The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis 61
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 61
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 60
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 60
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 60
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 60
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 60
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening 60
Synthesis and anticonvulsant activity of triazolo[4,5-c][2,3]benzodiazepines 59
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 59
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 59
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 59
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 59
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 58
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 58
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 58
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs) 58
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 57
HIV-1 RT inhibitors containing a cyclofunctionalized benzimidazole system 57
Synthesis and stereochemistry of novel thieno[3,4-b][1,4]diazepine. 57
Sintesi e proprietà anticonvulsivanti di 3-(1,3,4-tiadiazol-2-il)tiazolidin-4-oni. 57
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 57
AMINOPYRAZINYL DERIVATIVES - SYNTHESIS AND EVALUATION OF ANTIINFLAMMATORY AND RELATED ACTIVITIES 57
Composti a presumibile attività antitumorale. IV - Sintesi ed attività antileucemica di N,N'-di-[2-(1,3,4-tiadiazolil)]metilendiamine 1-sostituite 56
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 56
Efficient 3D Database screening for novel HIV-1 IN inhibitors 56
13C NMR study of tetrahydrothiazolo[3,2-d][1,4]benzodiazepin-3(2H)-ones. 56
7,8-Methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists. 56
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 56
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists 56
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome 56
Synthesis and pharmacological evaluation of 4-aryl-6,7- dimethoxyphthalazines as anticonvulsant agents 55
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 55
Synthesis, biological activity, pharmacokinetic properties and molecular modelling studies of novel 1H,3H-oxazolo[3,4-a]benzimidazoles: non-nucleoside HIV-1 reverse transcriptase inhibitor 55
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 55
Compounds with potential antitumor activity. Note VIII 1-Alkyl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines. 55
2,3-Benzodiazepines as potential AMPA receptors antagonists 55
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 55
Pyrrolo[1',2':1,2]imidazo[4,5-b]pyridines, pyrrolo[2',1':2,3]imidazo[4,5-c]pyridines and pyrrolo[2,1-f]purines as potential benzodiazepine receptor ligands. 55
Falcipain-2 inhibitors 55
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 54
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 54
Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists 54
A physico-chemical study on the interaction between papaverine and natural and modified beta-cyclodextrins 54
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 54
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 54
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 53
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 53
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 53
Synthesis of new 2,3-diaryl-1,3-thiazolidin-4-ones as anti-HIV agents 53
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 53
Structure-activity relationship of anti-HIV thiazolo[3,4-a]benzimidazole derivatives 53
Characterization of the binding site in a series of AMPA receptor antagonists. 53
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 53
Evaluation of curcumin irreversibility 53
Totale 7.004
Salva come PNG Salva come JPEG
Categoria #
all - tutte 52.378
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.378
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201922 0 0 0 0 0 0 0 0 0 0 5 17
2019/20202.544 499 223 14 212 11 257 326 276 22 308 376 20
2020/20212.494 258 19 401 67 90 277 20 257 79 249 163 614
2021/20221.983 21 393 31 81 95 5 126 73 35 69 351 703
2022/20235.522 437 437 233 441 443 593 131 324 2.211 20 183 69
2023/20241.118 138 189 87 268 123 122 21 47 8 85 30 0
Totale 15.467