IRIS
ZAPPALA', Maria
 Distribuzione geografica
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Continente #
NA - Nord America 7.212
EU - Europa 6.217
AS - Asia 1.800
AF - Africa 19
SA - Sud America 14
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 5
Totale 15.276
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Nazione #
US - Stati Uniti d'America 7.177
IE - Irlanda 1.786
SE - Svezia 1.466
CN - Cina 939
UA - Ucraina 836
IT - Italia 599
VN - Vietnam 556
DE - Germania 551
FI - Finlandia 294
GB - Regno Unito 275
SG - Singapore 160
AT - Austria 114
IN - India 93
FR - Francia 82
CZ - Repubblica Ceca 47
BE - Belgio 43
RU - Federazione Russa 42
PL - Polonia 32
CA - Canada 31
IR - Iran 18
NL - Olanda 16
JP - Giappone 9
CL - Cile 8
EU - Europa 8
LV - Lettonia 7
CH - Svizzera 5
KR - Corea 5
AU - Australia 4
NG - Nigeria 4
RO - Romania 4
ZA - Sudafrica 4
DZ - Algeria 3
LU - Lussemburgo 3
PE - Perù 3
SA - Arabia Saudita 3
TN - Tunisia 3
BD - Bangladesh 2
BG - Bulgaria 2
BR - Brasile 2
EE - Estonia 2
EG - Egitto 2
ES - Italia 2
HK - Hong Kong 2
ID - Indonesia 2
KG - Kirghizistan 2
MX - Messico 2
PA - Panama 2
PT - Portogallo 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
BY - Bielorussia 1
DK - Danimarca 1
EC - Ecuador 1
GR - Grecia 1
HR - Croazia 1
IL - Israele 1
IQ - Iraq 1
IS - Islanda 1
KZ - Kazakistan 1
MA - Marocco 1
MD - Moldavia 1
MU - Mauritius 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
SC - Seychelles 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 15.276
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Città #
Dublin 1.785
Jacksonville 1.624
Chandler 1.333
Nyköping 1.003
Dong Ket 554
Beijing 414
Ashburn 393
Princeton 326
Medford 300
Cambridge 283
Dearborn 260
Des Moines 229
Boardman 183
Messina 180
Ann Arbor 169
Vienna 114
Singapore 103
Lancaster 96
Jinan 76
San Mateo 73
Milan 70
Wilmington 69
Woodbridge 61
Nanjing 51
Shenyang 50
Los Angeles 44
Brno 43
Brussels 38
Hyderabad 34
Haikou 33
Zhengzhou 31
Hebei 30
Warsaw 30
Tianjin 29
Houston 28
Pune 28
Augusta 23
Taizhou 23
Ningbo 21
Nanchang 20
Fuzhou 19
New York 19
Norwalk 19
Munich 18
Seattle 18
Changsha 15
Hangzhou 15
Guangzhou 14
London 14
Ardabil 13
Taiyuan 13
Montpellier 12
Ottawa 12
Catania 11
Jiaxing 11
Montréal 11
Rome 11
Washington 11
Helsinki 10
Edinburgh 9
Mcallen 9
Monmouth Junction 9
Saint Petersburg 9
Bari 8
Brooklyn 8
Morikitamachi 8
Nuremberg 8
Santa Clara 8
West Jordan 8
Auburn Hills 7
Francofonte 7
Leawood 7
Siderno 7
Amsterdam 6
Berlin 6
Borghetto Santo Spirito 6
Clearwater 6
Francavilla di Sicilia 6
Mumbai 6
New Delhi 6
Riva 6
Aversa 5
Caltagirone 5
Chicago 5
Hanover 5
Hefei 5
Novokuznetsk 5
Riposto 5
Southampton 5
Bremen 4
Clifton 4
Frankfurt am Main 4
Nanning 4
Palermo 4
Santiago 4
Trecastagni 4
Bangalore 3
Boston 3
Cape Town 3
Dallas 3
Totale 10.760
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Nome #
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: synthesis and stereochemistry 194
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: stereochemistry and anticonvulsant activity 194
1-[3,5-bis(trifluoromethyl)phenyl]-1H,3H-thiazolo[3,4- a]benzimidazole 153
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 147
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 143
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 141
1-Adamantanamine derivatives as potential anti-HIV agents 135
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 132
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: non-competitive AMPA receptors antagonists 130
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni 3a-sostituiti 94
Ciclofunzionalizzazione di 1,4- e 1,5-benzodiazepine: sintesi e stereochimica di nuovi sistemi eteropoliciclici ottenuti per reazione con acidi mercaptoacetici 91
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 89
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells 87
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 86
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 81
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 80
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 79
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni isomeri ottenuti da 4-cloro-1,2-fenilendiamina ed acidi 3-acilpropionici 78
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 75
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 74
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 74
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 73
4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one 73
Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs) 73
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 72
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 71
Anti-HIV agents: design and discovery of new potent RT inhibitors 70
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 70
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 69
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 68
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 68
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 67
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 67
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 67
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 67
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 67
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 66
3H-Azirino[1,2-d][1,4]benzodiazepin-4(5H)-ones: synthesis and stereochemistry 66
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives 66
Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. 65
Synthesis and pharmacological evaluation of 4-aryl-6,7- dimethoxyphthalazines as anticonvulsant agents 64
Annelated 1,5-benzothiazepines 63
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 62
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 62
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 62
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 62
The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis 62
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening 62
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 61
High-performance liquid chromatographic determination of new 2,3-benzodiazepines 61
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 61
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 61
Synthesis and anticonvulsant activity of triazolo[4,5-c][2,3]benzodiazepines 60
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 60
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 60
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 60
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 60
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 60
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 60
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 59
Efficient 3D Database screening for novel HIV-1 IN inhibitors 59
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 59
AMINOPYRAZINYL DERIVATIVES - SYNTHESIS AND EVALUATION OF ANTIINFLAMMATORY AND RELATED ACTIVITIES 59
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs) 59
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 59
Composti a presumibile attività antitumorale. IV - Sintesi ed attività antileucemica di N,N'-di-[2-(1,3,4-tiadiazolil)]metilendiamine 1-sostituite 58
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 58
HIV-1 RT inhibitors containing a cyclofunctionalized benzimidazole system 58
13C NMR study of tetrahydrothiazolo[3,2-d][1,4]benzodiazepin-3(2H)-ones. 58
Synthesis and stereochemistry of novel thieno[3,4-b][1,4]diazepine. 58
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 58
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 57
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 57
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 57
Sintesi e proprietà anticonvulsivanti di 3-(1,3,4-tiadiazol-2-il)tiazolidin-4-oni. 57
A physico-chemical study on the interaction between papaverine and natural and modified beta-cyclodextrins 57
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 57
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists 57
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome 57
Synthesis, biological activity, pharmacokinetic properties and molecular modelling studies of novel 1H,3H-oxazolo[3,4-a]benzimidazoles: non-nucleoside HIV-1 reverse transcriptase inhibitor 56
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 56
7,8-Methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists. 56
Pyrrolo[1',2':1,2]imidazo[4,5-b]pyridines, pyrrolo[2',1':2,3]imidazo[4,5-c]pyridines and pyrrolo[2,1-f]purines as potential benzodiazepine receptor ligands. 56
Falcipain-2 inhibitors 56
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 56
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 55
Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists 55
Synthesis of new 2,3-diaryl-1,3-thiazolidin-4-ones as anti-HIV agents 55
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 55
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 55
Compounds with potential antitumor activity. Note VIII 1-Alkyl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines. 55
2,3-Benzodiazepines as potential AMPA receptors antagonists 55
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation 55
Design and NMR conformational analysis in solution of β5i-selective inhibitors of immunoproteasome 54
Selective induction of apoptosis in multidrug resistant HL60R cells by the thiazolobenzimidazole derivative TBZ. 54
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 54
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 54
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 54
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 54
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 54
Totale 7.137
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Categoria #
all - tutte 61.348
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.348
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.822 0 0 14 212 11 257 326 276 22 308 376 20
2020/20212.494 258 19 401 67 90 277 20 257 79 249 163 614
2021/20221.983 21 393 31 81 95 5 126 73 35 69 351 703
2022/20235.522 437 437 233 441 443 593 131 324 2.211 20 183 69
2023/20241.230 138 189 87 268 123 122 21 47 8 85 53 89
2024/2025231 113 78 40 0 0 0 0 0 0 0 0 0
Totale 15.810