IRIS
ZAPPALA', Maria
 Distribuzione geografica
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Continente #
NA - Nord America 7.233
EU - Europa 6.316
AS - Asia 2.429
AF - Africa 21
SA - Sud America 14
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 5
Totale 16.027
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Nazione #
US - Stati Uniti d'America 7.197
IE - Irlanda 1.787
SE - Svezia 1.466
CN - Cina 940
UA - Ucraina 839
SG - Singapore 782
IT - Italia 645
DE - Germania 573
VN - Vietnam 556
FI - Finlandia 312
GB - Regno Unito 278
AT - Austria 115
IN - India 98
FR - Francia 83
CZ - Repubblica Ceca 47
BE - Belgio 43
RU - Federazione Russa 43
CA - Canada 32
PL - Polonia 32
NL - Olanda 19
IR - Iran 18
JP - Giappone 9
CL - Cile 8
EU - Europa 8
LV - Lettonia 7
CH - Svizzera 5
DZ - Algeria 5
KR - Corea 5
AU - Australia 4
NG - Nigeria 4
RO - Romania 4
ZA - Sudafrica 4
ID - Indonesia 3
LU - Lussemburgo 3
PE - Perù 3
SA - Arabia Saudita 3
TN - Tunisia 3
BD - Bangladesh 2
BG - Bulgaria 2
BR - Brasile 2
EE - Estonia 2
EG - Egitto 2
ES - Italia 2
HK - Hong Kong 2
KG - Kirghizistan 2
MX - Messico 2
PA - Panama 2
PT - Portogallo 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
BY - Bielorussia 1
DK - Danimarca 1
EC - Ecuador 1
GR - Grecia 1
HR - Croazia 1
IL - Israele 1
IQ - Iraq 1
IS - Islanda 1
KZ - Kazakistan 1
MA - Marocco 1
MD - Moldavia 1
MU - Mauritius 1
MY - Malesia 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
SC - Seychelles 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 16.027
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Città #
Dublin 1.786
Jacksonville 1.624
Chandler 1.333
Nyköping 1.003
Singapore 643
Dong Ket 554
Beijing 414
Ashburn 393
Princeton 326
Medford 300
Cambridge 283
Dearborn 260
Des Moines 229
Messina 187
Boardman 183
Ann Arbor 169
Vienna 115
Lancaster 96
Jinan 76
San Mateo 73
Milan 70
Wilmington 69
Woodbridge 61
Nanjing 51
Shenyang 50
Los Angeles 45
Brno 43
Munich 40
Brussels 38
Hyderabad 34
Haikou 33
Zhengzhou 31
Hebei 30
Warsaw 30
Tianjin 29
Houston 28
Pune 28
Augusta 23
Taizhou 23
Helsinki 21
Ningbo 21
Aversa 20
Nanchang 20
Fuzhou 19
New York 19
Norwalk 19
Seattle 18
Changsha 15
Hangzhou 15
London 15
Rome 15
Guangzhou 14
Ardabil 13
Taiyuan 13
Montpellier 12
Ottawa 12
Catania 11
Jiaxing 11
Montréal 11
Mumbai 11
Santa Clara 11
Washington 11
Edinburgh 9
Mcallen 9
Monmouth Junction 9
Saint Petersburg 9
Amsterdam 8
Bari 8
Brooklyn 8
Morikitamachi 8
Nuremberg 8
West Jordan 8
Auburn Hills 7
Espoo 7
Francofonte 7
Leawood 7
Siderno 7
Berlin 6
Borghetto Santo Spirito 6
Clearwater 6
Francavilla di Sicilia 6
New Delhi 6
Riva 6
Caltagirone 5
Chicago 5
Hanover 5
Hefei 5
Novokuznetsk 5
Riposto 5
Southampton 5
Bremen 4
Clifton 4
Frankfurt am Main 4
Nanning 4
Palermo 4
Phoenix 4
Santiago 4
Trecastagni 4
Bangalore 3
Boston 3
Totale 11.378
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Nome #
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: synthesis and stereochemistry 201
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: stereochemistry and anticonvulsant activity 196
1-[3,5-bis(trifluoromethyl)phenyl]-1H,3H-thiazolo[3,4- a]benzimidazole 156
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 151
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 146
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 145
1-Adamantanamine derivatives as potential anti-HIV agents 141
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 136
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: non-competitive AMPA receptors antagonists 136
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni 3a-sostituiti 98
Ciclofunzionalizzazione di 1,4- e 1,5-benzodiazepine: sintesi e stereochimica di nuovi sistemi eteropoliciclici ottenuti per reazione con acidi mercaptoacetici 94
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni isomeri ottenuti da 4-cloro-1,2-fenilendiamina ed acidi 3-acilpropionici 94
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 91
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells 88
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 87
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 87
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 86
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 81
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 81
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 78
4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one 76
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 76
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 76
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 76
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 75
3H-Azirino[1,2-d][1,4]benzodiazepin-4(5H)-ones: synthesis and stereochemistry 74
Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs) 74
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 73
Anti-HIV agents: design and discovery of new potent RT inhibitors 71
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 71
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 71
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening 71
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 70
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 70
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 70
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 69
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 69
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives 69
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 69
Synthesis and pharmacological evaluation of 4-aryl-6,7- dimethoxyphthalazines as anticonvulsant agents 68
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 68
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 67
Annelated 1,5-benzothiazepines 67
13C NMR study of tetrahydrothiazolo[3,2-d][1,4]benzodiazepin-3(2H)-ones. 66
Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. 66
High-performance liquid chromatographic determination of new 2,3-benzodiazepines 65
Novel potent AMPA/kainate receptor antagonists: Synthesis and anticonvulsant activity of a series of 2-[(4- alkylsemicarbazono)-(4-aminophenyl)methyl]-4,5- methylenedioxyphenylacetic acid alkyl esters 65
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 64
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 64
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 64
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 64
The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis 64
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 64
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 63
Synthesis and anticonvulsant activity of triazolo[4,5-c][2,3]benzodiazepines 63
Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors 63
Synthesis and anticonvulsant activity of novel and potent 6,7- methylenedioxyphthalazin-1(2H)-ones 62
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 62
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 62
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 62
AMINOPYRAZINYL DERIVATIVES - SYNTHESIS AND EVALUATION OF ANTIINFLAMMATORY AND RELATED ACTIVITIES 62
STRATEGIES FOR SYNTHESIS OF CONFORMATIONALLY CONSTRAINED GLUTAMATE ANALOGUES 62
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 62
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 62
Composti a presumibile attività antitumorale. IV - Sintesi ed attività antileucemica di N,N'-di-[2-(1,3,4-tiadiazolil)]metilendiamine 1-sostituite 61
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents 61
Efficient 3D Database screening for novel HIV-1 IN inhibitors 61
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 61
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs) 61
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 61
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 60
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 60
HIV-1 RT inhibitors containing a cyclofunctionalized benzimidazole system 60
Synthesis and anticonvulsant activity of novel and potent 1- aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3- benzodiazepin-4-ones 60
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 60
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome 60
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 59
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 59
Synthesis and stereochemistry of novel thieno[3,4-b][1,4]diazepine. 59
Sintesi e proprietà anticonvulsivanti di 3-(1,3,4-tiadiazol-2-il)tiazolidin-4-oni. 59
Synthesis, biological activity, pharmacokinetic properties and molecular modelling studies of novel 1H,3H-oxazolo[3,4-a]benzimidazoles: non-nucleoside HIV-1 reverse transcriptase inhibitor 58
2,3-Benzodiazepines as potential AMPA receptors antagonists 58
A physico-chemical study on the interaction between papaverine and natural and modified beta-cyclodextrins 58
Pyrrolo[1',2':1,2]imidazo[4,5-b]pyridines, pyrrolo[2',1':2,3]imidazo[4,5-c]pyridines and pyrrolo[2,1-f]purines as potential benzodiazepine receptor ligands. 58
DEVELOPMENT OF NOVEL PEPTIDOMIMETICS CONTAINIG A VINYL SULFONE MOIETY AS PROTEASOME INHIBITORS 58
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists 58
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 58
Synthesis and anticonvulsant activity of novel and potent 2,3- benzodiazepine AMPA/kainate receptor antagonists 57
HIV-1 Integrase Inhibitors: Pharmacophore Modeling and Rational Drug Design 57
Development of nonpeptidic vinyl and allyl phosphonates as active-site-directed inhibitors of falcipain-2 57
Compounds with potential antitumor activity. Note VIII 1-Alkyl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines. 57
7,8-Methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists. 57
Falcipain-2 inhibitors 57
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 56
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 56
Synthesis of new 2,3-diaryl-1,3-thiazolidin-4-ones as anti-HIV agents 56
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli 1-sostituiti 56
Synthesis, chiral resolution and enantiopharmacology of a potent 2,3-benzodiazepine as noncompetitive AMPA receptor antagonist 56
TBZ-analoghi inibitori non nucleosidici della HIV-RT 56
Comparative anticonvulsant activity of new tricyclic benzodiazepines in DBA/2 mice. 56
Totale 7.446
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Categoria #
all - tutte 66.523
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 66.523
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.596 0 0 0 0 11 257 326 276 22 308 376 20
2020/20212.494 258 19 401 67 90 277 20 257 79 249 163 614
2021/20221.983 21 393 31 81 95 5 126 73 35 69 351 703
2022/20235.522 437 437 233 441 443 593 131 324 2.211 20 183 69
2023/20241.230 138 189 87 268 123 122 21 47 8 85 53 89
2024/2025988 113 78 136 430 231 0 0 0 0 0 0 0
Totale 16.567