IRIS
ZAPPALA', Maria
 Distribuzione geografica
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Continente #
NA - Nord America 20.380
EU - Europa 14.726
AS - Asia 7.657
SA - Sud America 2.555
AF - Africa 234
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 9
AN - Antartide 1
Totale 45.572
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Nazione #
US - Stati Uniti d'America 20.157
RU - Federazione Russa 7.474
SG - Singapore 3.145
BR - Brasile 2.216
CN - Cina 2.043
IE - Irlanda 1.787
SE - Svezia 1.496
VN - Vietnam 912
UA - Ucraina 871
HK - Hong Kong 776
IT - Italia 739
DE - Germania 706
FR - Francia 428
GB - Regno Unito 388
FI - Finlandia 341
IN - India 188
AT - Austria 133
AR - Argentina 114
CA - Canada 99
BD - Bangladesh 89
PL - Polonia 82
MX - Messico 78
TR - Turchia 73
IQ - Iraq 70
ZA - Sudafrica 58
NL - Olanda 57
CZ - Repubblica Ceca 51
MA - Marocco 51
EC - Ecuador 49
UZ - Uzbekistan 48
CO - Colombia 46
BE - Belgio 45
JP - Giappone 40
PK - Pakistan 35
VE - Venezuela 35
ID - Indonesia 33
CL - Cile 27
ES - Italia 27
TN - Tunisia 26
CI - Costa d'Avorio 21
PY - Paraguay 20
SA - Arabia Saudita 20
IR - Iran 19
PE - Perù 19
UY - Uruguay 18
AE - Emirati Arabi Uniti 17
DZ - Algeria 17
NP - Nepal 16
AZ - Azerbaigian 15
GE - Georgia 13
JM - Giamaica 13
KE - Kenya 13
LT - Lituania 13
IL - Israele 12
JO - Giordania 12
LV - Lettonia 12
EG - Egitto 11
MY - Malesia 11
BO - Bolivia 10
CH - Svizzera 10
KG - Kirghizistan 10
SN - Senegal 10
AL - Albania 8
EU - Europa 8
KZ - Kazakistan 8
LB - Libano 7
PA - Panama 7
RO - Romania 7
AU - Australia 6
BY - Bielorussia 6
HN - Honduras 6
KR - Corea 6
BA - Bosnia-Erzegovina 5
DO - Repubblica Dominicana 5
KW - Kuwait 5
OM - Oman 5
RS - Serbia 5
SY - Repubblica araba siriana 5
TT - Trinidad e Tobago 5
AM - Armenia 4
ET - Etiopia 4
GR - Grecia 4
LU - Lussemburgo 4
ML - Mali 4
MU - Mauritius 4
PH - Filippine 4
TH - Thailandia 4
AO - Angola 3
BG - Bulgaria 3
CR - Costa Rica 3
DK - Danimarca 3
EE - Estonia 3
GA - Gabon 3
HU - Ungheria 3
MD - Moldavia 3
NI - Nicaragua 3
PT - Portogallo 3
BN - Brunei Darussalam 2
CG - Congo 2
CY - Cipro 2
Totale 45.537
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Città #
Dallas 10.031
Moscow 2.313
Dublin 1.786
Singapore 1.686
Jacksonville 1.629
Chandler 1.329
Ashburn 1.245
Nyköping 999
Hong Kong 773
Beijing 702
Dong Ket 554
San Jose 366
Princeton 326
The Dalles 301
Medford 300
Cambridge 283
Lauterbourg 271
Los Angeles 266
Dearborn 260
Des Moines 231
Messina 220
Boardman 183
Ann Arbor 169
São Paulo 145
Buffalo 136
Vienna 120
Ho Chi Minh City 117
New York 116
Tianjin 114
Lancaster 96
Hanoi 88
Munich 88
Guangzhou 78
Redondo Beach 78
Jinan 76
Warsaw 76
Milan 75
San Mateo 73
Rio de Janeiro 69
Wilmington 69
Woodbridge 61
Belo Horizonte 60
Brooklyn 52
Frankfurt am Main 51
Nanjing 51
Shenyang 50
Tashkent 46
Orem 45
Brno 43
Santa Clara 42
Amsterdam 40
Chicago 40
Brussels 39
Houston 39
Montreal 39
Brasília 35
Hyderabad 35
Shanghai 35
Stockholm 35
Curitiba 33
Haikou 33
Johannesburg 33
Porto Alegre 33
Shenzhen 33
Zhengzhou 32
Hebei 30
London 30
Tokyo 30
San Francisco 29
Baghdad 28
Chennai 28
Pune 28
Campinas 27
Helsinki 27
Seattle 27
Poplar 26
Augusta 25
Denver 25
Mumbai 23
Phoenix 23
Rome 23
Taizhou 23
Boston 22
Nuremberg 22
Abidjan 21
Atlanta 21
Ningbo 21
Turku 21
Aversa 20
Nanchang 20
Council Bluffs 19
Fuzhou 19
Manchester 19
Norwalk 19
Dhaka 18
Hangzhou 18
Manaus 18
Mexico City 18
Quito 18
Salvador 18
Totale 29.676
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Nome #
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: synthesis and stereochemistry 4.725
[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines: stereochemistry and anticonvulsant activity 4.705
1-[3,5-bis(trifluoromethyl)phenyl]-1H,3H-thiazolo[3,4- a]benzimidazole 297
1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists 296
1-Phenyl-substituted 1H,3H-thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 287
1,3-Thiazolidin-4-ones: potent and selective anti-HIV-1 agents 270
1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: non-competitive AMPA receptors antagonists 267
1-Aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents 253
1-Adamantanamine derivatives as potential anti-HIV agents 249
1H,3H-Thiazolo[3,4-a]benzimidazoles and pharmaceutical compositions containing them 235
4,5-Dihydro-7,8-dimethoxy-1-phenyl-3H-2,3-benzodiazepin-4-one 207
3,5-dihydro-4H-2,3-benzodiazepine-4-thiones: A new class of AMPA receptor antagonists 206
2-(2,6-dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors 198
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni 3a-sostituiti 197
7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists 197
3H-AZIRINO[1,2-D][1,4]BENZODIAZEPIN-4 (5H)-ONES - SYNTHESIS AND STEREOCHEMISTRY 190
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 190
5H-[1,2,4]OXADIAZOLO[5,4-D][1,5]BENZOTHIAZEPINES - SYNTHESIS AND STEREOCHEMISTRY 188
2,3,3a,4-Tetraidro-1H-pirrolo[1,2-a]benzimidazol-1-oni isomeri ottenuti da 4-cloro-1,2-fenilendiamina ed acidi 3-acilpropionici 186
5H-[1,2,4]Oxadiazolo[5,4-d][1,5]benzothiazepines as anticonvulsant agents in DBA/2 mice. 186
3H-Azirino[1,2-d][1,4]benzodiazepin-4(5H)-ones: synthesis and stereochemistry 184
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 184
3,5-Dihydro-5-methyl-7,8-methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel noncompetitive AMPA receptor antagonists 177
Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors 175
Anti-HIV agents: design and discovery of new potent RT inhibitors 169
2,3-Benzodiazepines as potential AMPA receptors antagonists 169
Azirino[1,2-d][1,4]benzodiazepine derivatives and related 1,4- benzodiazepines as anticonvulsant agents in DBA/2 mice 169
4,4-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 168
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 168
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma cells 168
7,9-Dihydro-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-ones as anticonvulsant agents 167
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors. 166
13C NMR study of tetrahydrothiazolo[3,2-d][1,4]benzodiazepin-3(2H)-ones. 162
Cross-Metathesis Reactions in the Synthesis of Constrained Dipeptide Mimics as Potent Falcipain-2 Inhibitors 162
Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors 159
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 159
A simple and efficient synthesis of GYKI 52466 and GYKI 52895 158
Sintesi ed attività anti-HIV di 1H,3H-tiazolo[3,4-a]benzimidazoli-sostituiti 158
Design and NMR conformational analysis in solution of β5i-selective inhibitors of immunoproteasome 157
DEVELOPMENT OF NOVEL PEPTIDOMIMETIC ANALOGUES OF A HIGHLY POTENT AND SELECTIVE FALCIPAIN-2 INHIBITOR CONTANING A VINYL ESTER MOIETY 156
Design, synthesis and molecular modeling studies on peptidomimetic vinyl esters as falcipan-2 inhibitors 156
Anticonvulsant activity and plasma level of 2,3-benzodiazepin- 4-ones (CFMs) in genetically epilepsy-prone rats 155
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 155
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening 155
6,7-Methylenedioxyphtalazin-1(2H)-ones as novel and potent anticonvulsant agents 154
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT 151
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 151
Annelated 1,5-benzothiazepines 150
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 150
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain 149
Compounds with potential anti-tumor activity VII. Synthesis and anti-tumor activity of 1-aryl-N,N'-di(1,3,4-thiadiazol-2-yl)methylenediamines 149
Design, synthesis, structure-activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents 149
Development of novel amides as non covalent inhibitors of immunoproteasome 148
ANNELATED 1,5-BENZODIAZEPINES .2. 6 MEMBERED RINGS 147
ANNELATED 1,5-BENZODIAZEPINES .1. 3-MEMBERED, 4-MEMBERED, AND 5-MEMBERED RINGS. 147
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 147
6,7-Methylenedioxyquinazolin-4-ones as Anticonvulsant Agents 146
AMINOPYRAZINYL DERIVATIVES - SYNTHESIS AND EVALUATION OF ANTIINFLAMMATORY AND RELATED ACTIVITIES 146
Evaluation of curcumin irreversibility 146
4,5-Methylenedioxybenzene derivatives: synthesis and investigation of the mechanism of their anticonvulsant activity. 145
Design and synthesis of 2,3-diaryl-1,3-thiazolidin-4one potent HIV-1 RT-inhibitors. 144
Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist 143
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives 143
6,7-Metilendiossiftalazin-1(2H)-oni: una nuova classe di potenti agenti anticonvulsivanti. 142
6,7-Methylenedioxyphthalazin-1(2H)-ones as novel and potent anticonvulsant agents 142
Falcipain-2 inhibitors 141
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 141
ANTICONVULSANT ACTIVITY OF PYRROLO[1',2'-1,2]IMIDAZO[4,5- B]PYRIDINES, PYRROLO[2',1'-2,3]IMIDAZO[4,5-C] PYRIDINES AND PYRROLO[2,1-F]PURINES IN DBA/2 MICE 140
Development of pyridin-2-one derivatives as non-covalent inhibitors of immunoproteasome 140
Synthesis and metabolic study of 1H,3H-oxazolo[3,4-a]benzimidazoles, a new class of non-nucleoside HIV-1 RT-inhibitors. 139
Discovery of novel peptidomimetics containing a benzodiazepine scaffold as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 138
Development of Novel Peptidomimetics Containing a VinylSulfone Moiety as Proteasome Inhibitors 138
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones 137
Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma. 137
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti- HIV-1 agents 136
Development of novel 1,4-benzodiazepines as antitrypanosomal agents 136
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei hodesiense 136
Drug combination studies of isoquinolinone AM12 with curcumin or quercetin: a new combination strategy to synergistically inhibit 20S proteasome 135
Ciclofunzionalizzazione di 1,4- e 1,5-benzodiazepine: sintesi e stereochimica di nuovi sistemi eteropoliciclici ottenuti per reazione con acidi mercaptoacetici 135
Efficient 3D Database screening for novel HIV-1 IN inhibitors 134
7-Chloro-1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazole and 1-(2,6-difluorophenyl)-6-methyl-1H,3H- thiazolo[3,4-a]benzimidazole 134
COMPUTATIONAL APPROACHES IN DISCOVERING NOVEL ANTI-AIDS AGENTS 133
Novel peptidomimetics containing different α,β-unsaturated electrophilic functions, as falcipain-2 inhibitors 133
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin- 4-(thi)one derivatives 131
A physico-chemical study on the interaction between papaverine and natural and modified beta-cyclodextrins 130
Anti-HIV agents .4. Synthesis and in vitro anti-HIV activity of novel 1-(2,6-difluorophenyl)-1H,3H-thiazolo[3,4- a]benzimidazoles 130
2,3-Benzodiazepine-based noncompetitive AMPAR antagonists: design, synthesis, binding affinity and mechanism of inhibition of the GluR2Qflip homomeric receptor channel 130
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists 129
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 128
Cross-metathesis reactions applications to the synthesis of peptidomimetics as potent falcipain-2 inhibitors 127
Development of novel peptide-based Michael acceptors as antitrypanosomal agents 127
Synthesis and structural features of new cyclofunctionalized benzimidazoles 126
Anti-HIV agents II. Synthesis and in vitro anti-HIV activity of novel 1H,3H-thiazolo[3,4-a]benzimidazoles. 126
An unexpected reaction between 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzodiazepine and mercaptoacetic acid 126
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis 126
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 126
Pharmacophore-Based Design of HIV-1 Integrase Strand-Transfer Inhibitors 125
Design, synthesis and biological evaluation of peptidomimetics boronic acids targeting 20S proteasome 125
Synthesis of new potential HIV-1 integrase inhibitors 122
Anti-HIV agents. V. Synthesis, structure and in vitro anti-HIV activity of novel 1H,3H-naphtho[2 ',3 ': 4,5]imidazo[1,2- c]thiazoles 122
Totale 25.193
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Categoria #
all - tutte 125.996
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 125.996
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.026 0 0 0 0 0 0 0 0 0 249 163 614
2021/20221.983 21 393 31 81 95 5 126 73 35 69 351 703
2022/20235.506 436 434 232 440 443 591 131 323 2.206 20 181 69
2023/20241.223 138 189 87 267 123 122 21 47 6 85 49 89
2024/20255.685 113 76 136 430 234 102 101 1.258 1.525 285 457 968
2025/202624.927 635 3.566 7.543 1.343 1.301 4.004 2.135 1.999 1.925 476 0 0
Totale 46.168