MIRABILE, Salvatore
MIRABILE, Salvatore
Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali
1-Benzylpiperidine derivatives: design and synthesis of new compounds as tyrosinase inhibitors from Agaricus bisporus
2019-01-01 Mirabile, Salvatore; Vittorio, Serena; Germano', Maria Paola; Gitto, Rosaria; Rapisarda, Antonio; DE LUCA, Laura
4-Fluorobenzylpiperazine-Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase
2020-01-01 Vittorio, S.; Ielo, L.; Mirabile, S.; Gitto, R.; Fais, A.; Floris, S.; Rapisarda, A.; Germano, M. P.; De Luca, L.
Analysis of structure-activity relationships in a series of 4-(1-piperazinyl)phenol-based derivatives as competitive inhibitors of Tyrosinase
2021-01-01 Mirabile, Salvatore; Gitto, Rosaria; Cacciola, Anna; Germano', Maria Paola; DE LUCA, Laura
Chemical Profile and Health-Promoting Activities of Crataegus laciniata (Rosaceae) Flowers
2023-01-01 Mirabile, Salvatore; D'Angelo, Valeria; Germanò, Maria Paola; Pouramin Arabi, Shiva; Parisi, Valentina; Raimondo, Francesco Maria; Rosa, Emanuele
Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase
2023-01-01 Ricci, F.; Schira, K.; Khettabi, L.; Lombardo, L.; Mirabile, S.; Gitto, R.; Soler-Lopez, M.; Scheuermann, J.; Wolber, G.; De Luca, L.
Design, synthesis and in vitro evaluation of 4-fluorobenzyl- and 4-hydroxyphenyl-based compounds targeting tyrosinases
2021-01-01 Mirabile, Salvatore; DE LUCA, Laura; Ricci, Federico; Cacciola, Anna; Rapisarda, Antonio; Germano', Maria Paola; Gitto, Rosaria
Design, Synthesis, and in Vitro Evaluation of 4-(4-Hydroxyphenyl)piperazine-Based Compounds Targeting Tyrosinase
2022-01-01 Mirabile, S.; Germano, M. P.; Fais, A.; Lombardo, L.; Ricci, F.; Floris, S.; Cacciola, A.; Rapisarda, A.; Gitto, R.; De Luca, L.
Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity
2023-01-01 De Luca, L; Lombardo, L; Mirabile, S; Marrazzo, A; Dichiara, M; Cosentino, G; Amata, E; Gitto, R
Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety
2020-01-01 De Luca, L.; Germano, M. P.; Fais, A.; Pintus, F.; Buemi, M. R.; Vittorio, S.; Mirabile, S.; Rapisarda, A.; Gitto, R.
Discovery of a novel class of Tyrosinase inhibitors as antimelanogenic agents
2021-01-01 Mirabile, Salvatore; Gitto, Rosaria; Vittorio, Serena; Rapisarda, Antonio; Germano', Maria Paola; Antonella, Fais; DE LUCA, Laura
Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects
2021-01-01 Mirabile, S.; Vittorio, S.; Paola Germano, M.; Adornato, I.; Ielo, L.; Rapisarda, A.; Gitto, R.; Pintus, F.; Fais, A.; De Luca, L.
Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile
2019-01-01 Ielo, L.; Deri, B.; Germano, M. P.; Vittorio, S.; Mirabile, Salvatore; Gitto, R.; Rapisarda, A.; Ronsisvalle, S.; Floris, S.; Pazy, Y.; Fais, A.; Fishman, A.; De Luca, L.
Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors
2022-01-01 Mirabile, Salvatore; Ielo, Laura; Mariapaola, Germanò; Gitto, Rosaria; Pace, Vittorio; De Luca, Laura.
In silico approach to select new natural-based compounds targeting tyrosinase
2022-01-01 Mirabile, Salvatore; Mariapaola, Germanò; Lombardo, Lisa; De Luca, Laura.; Gitto, Rosaria
Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus
2023-01-01 Mirabile, S.; Ielo, L.; Lombardo, L.; Ricci, F.; Gitto, R.; Germano, M. P.; Pace, V.; De Luca, L.
Structural optimization and in vitro evaluation of new 1-(4-fluorobenzyl)piperazine derivatives as inhibitors of Tyrosinase from Agaricus bisporus
2020-01-01 Mirabile, Salvatore; Gitto, Rosaria; Vittorio, Serena; Rapisarda, Antonio; Germano', Maria Paola; DE LUCA, Laura
Structure- and ligand-based optimization of fragment binding tyrosinase from Agaricus bisporus to develop anti-melanogenic agents
2022-01-27 Mirabile, Salvatore
Structure- and Ligand-based optimization of fragment binding tyrosinase from Agaricus bisporus to develop anti-melanogenic agents
2022-01-01 Mirabile, Salvatore; DE LUCA, Laura; Germano', Maria Paola; Fais, Antonella; Gitto, Rosaria
Synthesis and biochemical evaluation of 5-(pyridin-4-yl)-4H-1,2,4-triazol-4-amine-based inhibitors of tyrosinase from Agaricus bisporus
2022-01-01 Gitto, Rosaria; Luca, Laura De; Mirabile, Salvatore; Ricci, Federico; Adornato, Ilenia; Cacciola, Anna; Germanò, Maria Paola
Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-openingen routeto halohydrins
2021-01-01 Ielo, L.; Miele, M.; Pillari, V.; Senatore, R.; Mirabile, S.; Gitto, R.; Holzer, W.; Alcantara, A. R.; Pace, V.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1-Benzylpiperidine derivatives: design and synthesis of new compounds as tyrosinase inhibitors from Agaricus bisporus | 1-gen-2019 | Mirabile, Salvatore; Vittorio, Serena; Germano', Maria Paola; Gitto, Rosaria; Rapisarda, Antonio; DE LUCA, Laura | |
| 4-Fluorobenzylpiperazine-Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase | 1-gen-2020 | Vittorio, S.; Ielo, L.; Mirabile, S.; Gitto, R.; Fais, A.; Floris, S.; Rapisarda, A.; Germano, M. P.; De Luca, L. | |
| Analysis of structure-activity relationships in a series of 4-(1-piperazinyl)phenol-based derivatives as competitive inhibitors of Tyrosinase | 1-gen-2021 | Mirabile, Salvatore; Gitto, Rosaria; Cacciola, Anna; Germano', Maria Paola; DE LUCA, Laura | |
| Chemical Profile and Health-Promoting Activities of Crataegus laciniata (Rosaceae) Flowers | 1-gen-2023 | Mirabile, Salvatore; D'Angelo, Valeria; Germanò, Maria Paola; Pouramin Arabi, Shiva; Parisi, Valentina; Raimondo, Francesco Maria; Rosa, Emanuele | |
| Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase | 1-gen-2023 | Ricci, F.; Schira, K.; Khettabi, L.; Lombardo, L.; Mirabile, S.; Gitto, R.; Soler-Lopez, M.; Scheuermann, J.; Wolber, G.; De Luca, L. | |
| Design, synthesis and in vitro evaluation of 4-fluorobenzyl- and 4-hydroxyphenyl-based compounds targeting tyrosinases | 1-gen-2021 | Mirabile, Salvatore; DE LUCA, Laura; Ricci, Federico; Cacciola, Anna; Rapisarda, Antonio; Germano', Maria Paola; Gitto, Rosaria | |
| Design, Synthesis, and in Vitro Evaluation of 4-(4-Hydroxyphenyl)piperazine-Based Compounds Targeting Tyrosinase | 1-gen-2022 | Mirabile, S.; Germano, M. P.; Fais, A.; Lombardo, L.; Ricci, F.; Floris, S.; Cacciola, A.; Rapisarda, A.; Gitto, R.; De Luca, L. | |
| Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity | 1-gen-2023 | De Luca, L; Lombardo, L; Mirabile, S; Marrazzo, A; Dichiara, M; Cosentino, G; Amata, E; Gitto, R | |
| Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety | 1-gen-2020 | De Luca, L.; Germano, M. P.; Fais, A.; Pintus, F.; Buemi, M. R.; Vittorio, S.; Mirabile, S.; Rapisarda, A.; Gitto, R. | |
| Discovery of a novel class of Tyrosinase inhibitors as antimelanogenic agents | 1-gen-2021 | Mirabile, Salvatore; Gitto, Rosaria; Vittorio, Serena; Rapisarda, Antonio; Germano', Maria Paola; Antonella, Fais; DE LUCA, Laura | |
| Evaluation of 4-(4-Fluorobenzyl)piperazin-1-yl]-Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects | 1-gen-2021 | Mirabile, S.; Vittorio, S.; Paola Germano, M.; Adornato, I.; Ielo, L.; Rapisarda, A.; Gitto, R.; Pintus, F.; Fais, A.; De Luca, L. | |
| Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile | 1-gen-2019 | Ielo, L.; Deri, B.; Germano, M. P.; Vittorio, S.; Mirabile, Salvatore; Gitto, R.; Rapisarda, A.; Ronsisvalle, S.; Floris, S.; Pazy, Y.; Fais, A.; Fishman, A.; De Luca, L. | |
| Exploring the chemical space of 3-chloro-4-fluorophenyl-based compounds as tyrosinase inhibitors | 1-gen-2022 | Mirabile, Salvatore; Ielo, Laura; Mariapaola, Germanò; Gitto, Rosaria; Pace, Vittorio; De Luca, Laura. | |
| In silico approach to select new natural-based compounds targeting tyrosinase | 1-gen-2022 | Mirabile, Salvatore; Mariapaola, Germanò; Lombardo, Lisa; De Luca, Laura.; Gitto, Rosaria | |
| Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus | 1-gen-2023 | Mirabile, S.; Ielo, L.; Lombardo, L.; Ricci, F.; Gitto, R.; Germano, M. P.; Pace, V.; De Luca, L. | |
| Structural optimization and in vitro evaluation of new 1-(4-fluorobenzyl)piperazine derivatives as inhibitors of Tyrosinase from Agaricus bisporus | 1-gen-2020 | Mirabile, Salvatore; Gitto, Rosaria; Vittorio, Serena; Rapisarda, Antonio; Germano', Maria Paola; DE LUCA, Laura | |
| Structure- and ligand-based optimization of fragment binding tyrosinase from Agaricus bisporus to develop anti-melanogenic agents | 27-gen-2022 | Mirabile, Salvatore | |
| Structure- and Ligand-based optimization of fragment binding tyrosinase from Agaricus bisporus to develop anti-melanogenic agents | 1-gen-2022 | Mirabile, Salvatore; DE LUCA, Laura; Germano', Maria Paola; Fais, Antonella; Gitto, Rosaria | |
| Synthesis and biochemical evaluation of 5-(pyridin-4-yl)-4H-1,2,4-triazol-4-amine-based inhibitors of tyrosinase from Agaricus bisporus | 1-gen-2022 | Gitto, Rosaria; Luca, Laura De; Mirabile, Salvatore; Ricci, Federico; Adornato, Ilenia; Cacciola, Anna; Germanò, Maria Paola | |
| Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-openingen routeto halohydrins | 1-gen-2021 | Ielo, L.; Miele, M.; Pillari, V.; Senatore, R.; Mirabile, S.; Gitto, R.; Holzer, W.; Alcantara, A. R.; Pace, V. |