The present study aimed to verify whether a-inhibin expression occurs in canine ovarian neoplasms. 19 ovarian neoplasms of bitches following ovariohysterectomy, were investigated using immunohistochemistry for alpha inhibin subunit antigen.The selected neoplasms included 6 stromal tumours, 9 epithelial tumours and 4 germ cell tumours. A strong a-inhibin immunostaining was found in all granulosa cell tumours. In comparison, thecomas showed a moderate, focal immunoreaction, but negative results were common in both epithelial and germ-cell neoplasms. Alpha inhibin can be regarded as a histogenetic marker of stromal tumours.
Alpha-inhibin expression in canine ovarian neoplasms: Preliminary results
MARINO, Gabriele;NICOTINA, Piero Antonio;CATONE, Giuseppe;BONTEMPO, Rosa Angela;ZANGHI', Antonina
2003-01-01
Abstract
The present study aimed to verify whether a-inhibin expression occurs in canine ovarian neoplasms. 19 ovarian neoplasms of bitches following ovariohysterectomy, were investigated using immunohistochemistry for alpha inhibin subunit antigen.The selected neoplasms included 6 stromal tumours, 9 epithelial tumours and 4 germ cell tumours. A strong a-inhibin immunostaining was found in all granulosa cell tumours. In comparison, thecomas showed a moderate, focal immunoreaction, but negative results were common in both epithelial and germ-cell neoplasms. Alpha inhibin can be regarded as a histogenetic marker of stromal tumours.File in questo prodotto:
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