Objectives: The aim of this study was to assess gender related differences in the clinical and instrumental presentation of OSAS. Methods: 141 consecutive OSAS patients were evaluated as far as anthropometric measures, daytime and nocturnal symptoms, psychometric scales (Epworth Sleepiness Scale- ESS, SF-36v2, Beck Depression Inventory-BDI, Hamilton Anxiety Scale-HAMA, Pittsburgh Quality Index-PQI), comorbidities, ambulatory cardio-respiratory monitoring. Results: 46/141 patients were females (mean age 56.2), 96 males (mean age 55). Females had a significantly higher BMI (mean 33.85) than males (mean 31,6, p<0.05), whereas neck circumference was larger in males (p<0.0001). A positive familial history of snoring was higher in females (58%, p>0.2), with a 9.3 years for females and 15.2 for males (p<0.002). Most frequent symptoms in women were headache and asthenia upon awakening whereas a significant difference was seen as for attention and memory deficits. Both genders reported EDS but an ESS score ≥10 was seen more frequently in females. Apnoea/hypopnoea Index instead was higher in males (meanAHI 34.5, p<0.01). Hypothyroidism was overrepresented in females (p<0.005). On SF-36v2 women showed a worse quality of life both as PCS (p<0.001) as MCS (p>0.05), worse sleep quality on PQI (p<0.05), moderate mood disturbance on BDI (p<0.05), moderate anxiety on HAMA (p<0.02) than men. Conclusions: Unexpectedly OSAS males had a lower BMI compared to females. Females had more hypothyroidism but a similar rate of hypertension, dislipidemia and GERD. Finally, women had a worse quality of life and sleep with depression and anxiety than men.

Obstructive sleep apnoea syndrome(OSAS) in women and men: genderrelated differences

CONDURSO, ROSARIA;SERRA, Salvatore;SILVESTRI, Rosalia
2010-01-01

Abstract

Objectives: The aim of this study was to assess gender related differences in the clinical and instrumental presentation of OSAS. Methods: 141 consecutive OSAS patients were evaluated as far as anthropometric measures, daytime and nocturnal symptoms, psychometric scales (Epworth Sleepiness Scale- ESS, SF-36v2, Beck Depression Inventory-BDI, Hamilton Anxiety Scale-HAMA, Pittsburgh Quality Index-PQI), comorbidities, ambulatory cardio-respiratory monitoring. Results: 46/141 patients were females (mean age 56.2), 96 males (mean age 55). Females had a significantly higher BMI (mean 33.85) than males (mean 31,6, p<0.05), whereas neck circumference was larger in males (p<0.0001). A positive familial history of snoring was higher in females (58%, p>0.2), with a 9.3 years for females and 15.2 for males (p<0.002). Most frequent symptoms in women were headache and asthenia upon awakening whereas a significant difference was seen as for attention and memory deficits. Both genders reported EDS but an ESS score ≥10 was seen more frequently in females. Apnoea/hypopnoea Index instead was higher in males (meanAHI 34.5, p<0.01). Hypothyroidism was overrepresented in females (p<0.005). On SF-36v2 women showed a worse quality of life both as PCS (p<0.001) as MCS (p>0.05), worse sleep quality on PQI (p<0.05), moderate mood disturbance on BDI (p<0.05), moderate anxiety on HAMA (p<0.02) than men. Conclusions: Unexpectedly OSAS males had a lower BMI compared to females. Females had more hypothyroidism but a similar rate of hypertension, dislipidemia and GERD. Finally, women had a worse quality of life and sleep with depression and anxiety than men.
2010
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/2143075
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