An effective electrode modification strategy, integrated in a miniaturized silicon biosensor, was investigated for the rapid and sensitive electrochemical detection of low amount of DNA without PCR step. The miniaturized biosensor here presented is composed of three planar microelectrodes for electrochemical transduction of hybridized DNA target on working electrode, the hybridization is probed by the intercalation of Osmium redox probe.
Electrochemical biosensor for PCR free nucleic acids detection: A novel biosensor containing three planar microelectrodes for melocular diagnostic applications
Conoci, Sabrina
;Di Pietro, Maria L.;Sciuto, Emanuele L.;
2017-01-01
Abstract
An effective electrode modification strategy, integrated in a miniaturized silicon biosensor, was investigated for the rapid and sensitive electrochemical detection of low amount of DNA without PCR step. The miniaturized biosensor here presented is composed of three planar microelectrodes for electrochemical transduction of hybridized DNA target on working electrode, the hybridization is probed by the intercalation of Osmium redox probe.File in questo prodotto:
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Descrizione: Electrochemical Biosensor for PCR free Nucleic Acids Detection
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