The present invention relates to anticancer therapy in patients bearing tumors overexpressing Trop-2, by means of drugs directed against a component of the the signalling network of Trop-2, wherein said component is Akt. Trop-2 overexpression can also be exploited for the screening in vitro and in vivo of the anticancer activity of new compounds.
USE OF TROP-2 AS PREDICTIVE MARKER OF RESPONSE TO ANTI-TUMOR THERAPY BASED ON INHIBITORS OF AKT
alberti Saverio
Conceptualization
;
2013-01-01
Abstract
The present invention relates to anticancer therapy in patients bearing tumors overexpressing Trop-2, by means of drugs directed against a component of the the signalling network of Trop-2, wherein said component is Akt. Trop-2 overexpression can also be exploited for the screening in vitro and in vivo of the anticancer activity of new compounds.File in questo prodotto:
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