LymphomashavebecomethemostcommonAIDS-relatedcancerinthedevelopedworld,constitutingover50%ofallAIDSdefiningcancersandthemostcommoncauseofcancer-relateddeathinHIVinfectedindividuals Lymphocyte-to-monocyteratio(LMR),neutrophil-to-lymphocyteratio(NLR)andplatelet-to-lymphocyteratio(PLR)aresimpleandeffectivebiomarkersforbothhostimmunehomeostasis(e.g.,ALC,tumor-infiltratinglymphocytes)andthetumormicroenvironment(e.g.,AMC,tumor-associatemacrophages)thatmaypredictclinicaloutcomesinnon-Hodgkinlymphomas. However,theassociationbetweenthesehematologicparametersandprognosisofHIV-associatedlymphomas(HIV-L)hasnotbeenevaluated.
Outcome of HIV-associated non-Hodgkin lymphomas can be predicted by lymphocyte-to.monocyte ratio and platelet-to-lymphocite ratio.
G. Nunnari;G. F. Pellicanò.
2017-01-01
Abstract
LymphomashavebecomethemostcommonAIDS-relatedcancerinthedevelopedworld,constitutingover50%ofallAIDSdefiningcancersandthemostcommoncauseofcancer-relateddeathinHIVinfectedindividuals Lymphocyte-to-monocyteratio(LMR),neutrophil-to-lymphocyteratio(NLR)andplatelet-to-lymphocyteratio(PLR)aresimpleandeffectivebiomarkersforbothhostimmunehomeostasis(e.g.,ALC,tumor-infiltratinglymphocytes)andthetumormicroenvironment(e.g.,AMC,tumor-associatemacrophages)thatmaypredictclinicaloutcomesinnon-Hodgkinlymphomas. However,theassociationbetweenthesehematologicparametersandprognosisofHIV-associatedlymphomas(HIV-L)hasnotbeenevaluated.File in questo prodotto:
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