EradicationofHCVaftertherapywithinterferonplusribavirininHIV/HCV-coinfectedpatientsisassociatednotonlywithareductioninliver-relatedeventsbutalsowithareductioninHIVprogressionandmortalitynotrelatedtoliverdisease(Berenguer,ClinInfectDis2012). •HCV-HIVpatientshada50-75%increasedriskofCKDcomparedwithHIVpatients(Mocroft,AIDS2007;Wyatt,AIDS2008). •SuccessfulHCVtreatmentseemstoslightlyreducetheincidenceofchronickidneydiseases(Kovari,ClinInfectDis2017). •Concomitanttreatmentwithledipasvir/sofosbuvirandtenofovirhasbeenreportedasdetrimentalonkidneyfunction(Bunnell,Pharmacother2016).
Evolution of renal function during treatment with direct antiviral agents (DAA-t) in HIV/HCV infected patients in ICONA/HepaIcona cohorts.
G. Nunnari;G. F. Pellicanò.
2017-01-01
Abstract
EradicationofHCVaftertherapywithinterferonplusribavirininHIV/HCV-coinfectedpatientsisassociatednotonlywithareductioninliver-relatedeventsbutalsowithareductioninHIVprogressionandmortalitynotrelatedtoliverdisease(Berenguer,ClinInfectDis2012). •HCV-HIVpatientshada50-75%increasedriskofCKDcomparedwithHIVpatients(Mocroft,AIDS2007;Wyatt,AIDS2008). •SuccessfulHCVtreatmentseemstoslightlyreducetheincidenceofchronickidneydiseases(Kovari,ClinInfectDis2017). •Concomitanttreatmentwithledipasvir/sofosbuvirandtenofovirhasbeenreportedasdetrimentalonkidneyfunction(Bunnell,Pharmacother2016).File in questo prodotto:
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