Background: Persons living with HIV/AIDS (PWHAs) show an increased incidence of malignancies than the general population, especially of virus-related cancers either AIDS-defining malignancies (ADMs), and among non-AIDS defining malignancies (NADMs) of virus-related e.g. Hodgkin's lymphoma, HCC or anal/cervical cancer. In this study, we compare the incidence of cancer in a Large Italian cohort of ARTnaïve PWHAs in the last 20 years (ICONA cohort) with the general population, investigating the effect of age, CD4 and use of combined antiretroviral therapy (cART).
Non-AIDS related cancer risk is not affected by cART in ICONA cohort.
G. Nunnari;G. F. Pellicanò.
2018-01-01
Abstract
Background: Persons living with HIV/AIDS (PWHAs) show an increased incidence of malignancies than the general population, especially of virus-related cancers either AIDS-defining malignancies (ADMs), and among non-AIDS defining malignancies (NADMs) of virus-related e.g. Hodgkin's lymphoma, HCC or anal/cervical cancer. In this study, we compare the incidence of cancer in a Large Italian cohort of ARTnaïve PWHAs in the last 20 years (ICONA cohort) with the general population, investigating the effect of age, CD4 and use of combined antiretroviral therapy (cART).File in questo prodotto:
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