Background: Although overall response to modern first-line antiretroviral (ARV) regimens is >90% in clinical trials, high pre-ARV viral load (VL) can delay or hamper the chance of HIV-RNA suppression. There is debate regarding the optimal management of patients with high VL and whether VL kinetics during treatment is predictive of virological failure remains unestablished.
HIV viral load kinetics during first-line antiretroviral treatment and risk of virological non-response or rebound among patient with high pre-treatment HIV-RNA.
G. Nunnari;G. F. Pellicanò.
2018-01-01
Abstract
Background: Although overall response to modern first-line antiretroviral (ARV) regimens is >90% in clinical trials, high pre-ARV viral load (VL) can delay or hamper the chance of HIV-RNA suppression. There is debate regarding the optimal management of patients with high VL and whether VL kinetics during treatment is predictive of virological failure remains unestablished.File in questo prodotto:
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