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EnglishSwitching to a TAF-based or to TDF-sparing (dual combination, DC) regimens is considered as safer than continuing to take TDF-containing regimens, particularly for bone/kidney health. The main aim of this analysis was to evaluate the possible impact of recent results from randomised studies, which led to a change in treatment guidelines, on the observed rate of switch from TDF to TAF-based regimens or TDF-sparing DC in real-life and to identify the determinants of switch separately for the two strategies, with focus on current eGFR values.
| Titolo: | Determinants of switching to TAF-based cART or dual combinations (DC) from TDF-based regimens in a cohort of HIV-infected individuals with controlled viral load <50 copies/mL. |
| Autori: | |
| Data di pubblicazione: | 2019 |
| Rivista: | |
| Abstract: | Switching to a TAF-based or to TDF-sparing (dual combination, DC) regimens is considered as safer than continuing to take TDF-containing regimens, particularly for bone/kidney health. The main aim of this analysis was to evaluate the possible impact of recent results from randomised studies, which led to a change in treatment guidelines, on the observed rate of switch from TDF to TAF-based regimens or TDF-sparing DC in real-life and to identify the determinants of switch separately for the two strategies, with focus on current eGFR values. |
| Handle: | http://hdl.handle.net/11570/3147223 |
| Appare nelle tipologie: | 14.d.1 Abstract in Atti di convegno |
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