The composition and the development of the HIV-DNA reservoir either in treated or untreated patients is determined by integrated mechanism comprising virological factors, immune system and treatment strategies (1). HLA types have been associated with varying rate of disease progression and different effects have been reported between subtypes of HLA alleles (2). HLA B*27 and HLA B*57 are associated with a slower rate of HIV disease progression, and HLA Class II DRB1*13:03 is associated with a lower plasma viral load in chronic HIV infection.

HIV-DNA levels, HLA-B*27 and HLA-DRB*13 among LTNPs, ECs and HIV controllers.

G. Nunnari;G. F. Pellicanò.
2019-01-01

Abstract

The composition and the development of the HIV-DNA reservoir either in treated or untreated patients is determined by integrated mechanism comprising virological factors, immune system and treatment strategies (1). HLA types have been associated with varying rate of disease progression and different effects have been reported between subtypes of HLA alleles (2). HLA B*27 and HLA B*57 are associated with a slower rate of HIV disease progression, and HLA Class II DRB1*13:03 is associated with a lower plasma viral load in chronic HIV infection.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3147225
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