Abstract Age-related medical disorders are increasing worldwide. Particularly, Type 2 Diabetes Mellitus (T2DM) is a chronic disease which largely affects general population, exceeding 90% of DM total amount. As psychopathological symptoms frequently occur in chronic medical conditions, our study aimed at exploring the relationship between psychological factors and metabolic control and its impact on health related quality of life (QoL). A convenience sample of forty-five out-patients with T2DM (65.3±5.9 yr.) was consecutively recruited and assessed through: Hamilton Anxiety Rating Scale (HAM-A), Beck Depression Inventory II edition (BDI-II) and 36-Item Short Form Survey (SF-36). Body mass index, time since DM diagnosis and glycated hemoglobin value were detected. Patients had a mean time since diagnosis of 11.6±6.7 yr. and an adequate metabolic control. Median HAM-A [25(20.7-30.6)], considering both somatic and psychic anxiety, was demonstrative of high anxiety levels, while lower depressive symptoms were observed [BDI-II: 13(8.3-21.4)]. A multiple regression analysis, after correcting for age, BMI, HbA1c value and BDI-II score, showed the health related QoL, relatively to Physical Component Summary (PCS), was significantly related to both disease duration (β=0.55, p=0.03, SE=0.25) and HAM-A scores (β=0.52, p=0.04, SE=0.24). Furthermore, both HAM-A (β=-0.67, p=0.01, SE=0.26) and BDI-II (β=-0.48, p=0.02, SE=0.20) scores were predictive of Mental Component Summary (MCS), while metabolic control was not an independent determinant. Our study suggests a possible predictive role of both anxiety levels and time since diagnosis in health related QoL in patients with T2DM. PCS was significantly associated with anxiety and time since diagnosis, while MCS was associated with anxiety and depressive symptoms. These results encourage to program T2DM psychological training to improve both disease self- management and health related QoL, in a such long duration disease.
Health related quality of life and anxiety in patients with Type 2 Diabetes Mellitus
Gabriella Martino
Conceptualization
;Antonino CatalanoFormal Analysis
;Federica BelloneInvestigation
;Nunziata MorabitoSupervision
;Maria Catena QuattropaniSupervision
2019-01-01
Abstract
Abstract Age-related medical disorders are increasing worldwide. Particularly, Type 2 Diabetes Mellitus (T2DM) is a chronic disease which largely affects general population, exceeding 90% of DM total amount. As psychopathological symptoms frequently occur in chronic medical conditions, our study aimed at exploring the relationship between psychological factors and metabolic control and its impact on health related quality of life (QoL). A convenience sample of forty-five out-patients with T2DM (65.3±5.9 yr.) was consecutively recruited and assessed through: Hamilton Anxiety Rating Scale (HAM-A), Beck Depression Inventory II edition (BDI-II) and 36-Item Short Form Survey (SF-36). Body mass index, time since DM diagnosis and glycated hemoglobin value were detected. Patients had a mean time since diagnosis of 11.6±6.7 yr. and an adequate metabolic control. Median HAM-A [25(20.7-30.6)], considering both somatic and psychic anxiety, was demonstrative of high anxiety levels, while lower depressive symptoms were observed [BDI-II: 13(8.3-21.4)]. A multiple regression analysis, after correcting for age, BMI, HbA1c value and BDI-II score, showed the health related QoL, relatively to Physical Component Summary (PCS), was significantly related to both disease duration (β=0.55, p=0.03, SE=0.25) and HAM-A scores (β=0.52, p=0.04, SE=0.24). Furthermore, both HAM-A (β=-0.67, p=0.01, SE=0.26) and BDI-II (β=-0.48, p=0.02, SE=0.20) scores were predictive of Mental Component Summary (MCS), while metabolic control was not an independent determinant. Our study suggests a possible predictive role of both anxiety levels and time since diagnosis in health related QoL in patients with T2DM. PCS was significantly associated with anxiety and time since diagnosis, while MCS was associated with anxiety and depressive symptoms. These results encourage to program T2DM psychological training to improve both disease self- management and health related QoL, in a such long duration disease.Pubblicazioni consigliate
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