In the continuous attempt to reach high performing therapeutic tools, the attention was focused on the development of multimodal nanodevices combining the properties of therapeutic agents with the detectability of contrast ones, providing all-in-one nanomedicine tools. In the present work, we discuss the synthesis, the characterization, and the biological profile of a new fluorescent hybrid nanodevice based on the combination of cationic cyclodextrin and graphene (GCD@Ada-Rhod, see Figure 1). Additionally, the performance of GCD@Ada-Rhod as miRNA nanocarrier and its ability to modify the expression of cancer-correlated genes were investigated. [1-2]
Multifunctional fluorescent Graphene-Cyclodextrin nanoplatforms
Giulia Neri
Primo
;Angela Scala;Antonino Mazzaglia;Anna PipernoUltimo
2021-01-01
Abstract
In the continuous attempt to reach high performing therapeutic tools, the attention was focused on the development of multimodal nanodevices combining the properties of therapeutic agents with the detectability of contrast ones, providing all-in-one nanomedicine tools. In the present work, we discuss the synthesis, the characterization, and the biological profile of a new fluorescent hybrid nanodevice based on the combination of cationic cyclodextrin and graphene (GCD@Ada-Rhod, see Figure 1). Additionally, the performance of GCD@Ada-Rhod as miRNA nanocarrier and its ability to modify the expression of cancer-correlated genes were investigated. [1-2]Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.