The effect of polycyclic musk compound on fish organism

The effect of tonalide, known as polycyclic musk compound, was studied on rainbow trout. Total of 65 individuals were acclimatized and consequently exposed to two tonalide concentrations – one environmentally-relevant (854 μg/kg); the second one 10× higher for evaluation of dose-dependent effect (8,699 μg/kg). The tonalide was incorporated into feed and fish were fed twice a day in amount 1% of their body weight. After six weeks of experimental phase, fish were sampled for gaining data for the biometrical, haematological, bio chemical and oxidative stress analysis and for evaluation of endocrine disruption using plasma vitellogenin. In conclusion, the biochemical and oxidative stress parameters did not revealed any changes. In haematological profile, only the haematocrit was increased as reaction on both concentrations of tonalide. The endocrine disruption caused by tonalide was not observed in rainbow trout.