The possible inclusion of natural substances in analgesia protocol may lead to new scenario the control of animal pain. The purpose of this study was to evaluate the usefulness of a preparation based on Hemp Oil, CBD 2% and Boswellia for intra- and post-operative pain and to compare it with Tramadol, the classic analgesic most used so far1,2. Twenty dogs arrived in the clinic for orthopedic problems were enrolled in the study and they were divided into two groups of ten subjects each. The first group (Control Group) was administered Tramadol 5 mg/kg bid/os, given on the three days before surgery. The second group (Experimental Group) was administered the combination of hemp oil/CBD 2% /boswellia 5 mg/Kg bid/os for the three days before surgery. Anesthesia was performed with methadone 0.2 mg/kg intramuscularly, followed by Propofol 5 mg/kg and maintenance with oxygen and Isoflurane at variable flows. The parameters including heart rate, respiratory rate, pressure, pulse oximetry, capnography, percentage of anesthetic agent (MAC) and body temperature were collected and monitored during anesthesia. Patients, in the postoperative period, were evaluated with the Glasgow Composite Pain Scale. Respiratory rate was reduced in the two groups with lower values in the tramadol-treated group. Heart rate and maximal blood pressure were reduced and maintained within physiological ranges; no significant differences were noted between the two groups. Saturation and the percentage of carbon dioxide at the end of the expiratory act had a regular trend in both groups. Minimum alveolar concentration varied significantly in both groups during all phases of anesthesia. Interestingly, the hemp oil/CBD 2%/boswellia group maintained significantly lower delivered anesthetic values than the tramadol group. Patient assessed with the Glasgow Composite Pain Scale on the day after surgery showed that there were no significant differences in the two groups. Though further studies are advocated, according to the findings obtained in the current survey, it could be suggested that the use of combination of hemp oil/CBD 2%/boswellia produced stable anesthesia and good analgesia.
Orthopedic pain control in dogs using Hemp Oil/CBG2% and Boswellia Serrata.
Claudia Interlandi
Primo
;Rosalia CrupiSecondo
;Francesca ArfusoPenultimo
;Enrico Gugliandolo.Ultimo
2022-01-01
Abstract
The possible inclusion of natural substances in analgesia protocol may lead to new scenario the control of animal pain. The purpose of this study was to evaluate the usefulness of a preparation based on Hemp Oil, CBD 2% and Boswellia for intra- and post-operative pain and to compare it with Tramadol, the classic analgesic most used so far1,2. Twenty dogs arrived in the clinic for orthopedic problems were enrolled in the study and they were divided into two groups of ten subjects each. The first group (Control Group) was administered Tramadol 5 mg/kg bid/os, given on the three days before surgery. The second group (Experimental Group) was administered the combination of hemp oil/CBD 2% /boswellia 5 mg/Kg bid/os for the three days before surgery. Anesthesia was performed with methadone 0.2 mg/kg intramuscularly, followed by Propofol 5 mg/kg and maintenance with oxygen and Isoflurane at variable flows. The parameters including heart rate, respiratory rate, pressure, pulse oximetry, capnography, percentage of anesthetic agent (MAC) and body temperature were collected and monitored during anesthesia. Patients, in the postoperative period, were evaluated with the Glasgow Composite Pain Scale. Respiratory rate was reduced in the two groups with lower values in the tramadol-treated group. Heart rate and maximal blood pressure were reduced and maintained within physiological ranges; no significant differences were noted between the two groups. Saturation and the percentage of carbon dioxide at the end of the expiratory act had a regular trend in both groups. Minimum alveolar concentration varied significantly in both groups during all phases of anesthesia. Interestingly, the hemp oil/CBD 2%/boswellia group maintained significantly lower delivered anesthetic values than the tramadol group. Patient assessed with the Glasgow Composite Pain Scale on the day after surgery showed that there were no significant differences in the two groups. Though further studies are advocated, according to the findings obtained in the current survey, it could be suggested that the use of combination of hemp oil/CBD 2%/boswellia produced stable anesthesia and good analgesia.Pubblicazioni consigliate
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