The combined use of multidimensional gas chromatography (MDGC)—in either heart-cutting or comprehensive configuration—to mass spectrometry (MS) generates a very powerful three-dimensional platform. The potential of MDGC-MS within the context of various scenarios is herein described and highlighted; technical aspects related to such a hyphenation are also discussed. The combination of heart-cutting MDGC with MS is much more established and is characterized by no specific technical difficulties (practically the same as for GC-MS instrumentation). For such a reason, particular focus will be devoted to the combination comprehensive MDGC-MS, and on aspects related to its evolution mainly after 2010.

Multidimensional gas chromatography: Hyphenation with mass spectrometry

Tranchida Peter Q.
;
Giocastro B.;Mondello L.
2022-01-01

Abstract

The combined use of multidimensional gas chromatography (MDGC)—in either heart-cutting or comprehensive configuration—to mass spectrometry (MS) generates a very powerful three-dimensional platform. The potential of MDGC-MS within the context of various scenarios is herein described and highlighted; technical aspects related to such a hyphenation are also discussed. The combination of heart-cutting MDGC with MS is much more established and is characterized by no specific technical difficulties (practically the same as for GC-MS instrumentation). For such a reason, particular focus will be devoted to the combination comprehensive MDGC-MS, and on aspects related to its evolution mainly after 2010.
2022
9780323988810
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3230392
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