The combined use of multidimensional gas chromatography (MDGC)—in either heart-cutting or comprehensive configuration—to mass spectrometry (MS) generates a very powerful three-dimensional platform. The potential of MDGC-MS within the context of various scenarios is herein described and highlighted; technical aspects related to such a hyphenation are also discussed. The combination of heart-cutting MDGC with MS is much more established and is characterized by no specific technical difficulties (practically the same as for GC-MS instrumentation). For such a reason, particular focus will be devoted to the combination comprehensive MDGC-MS, and on aspects related to its evolution mainly after 2010.
Multidimensional gas chromatography: Hyphenation with mass spectrometry
Tranchida Peter Q.
;Giocastro B.;Mondello L.
2022-01-01
Abstract
The combined use of multidimensional gas chromatography (MDGC)—in either heart-cutting or comprehensive configuration—to mass spectrometry (MS) generates a very powerful three-dimensional platform. The potential of MDGC-MS within the context of various scenarios is herein described and highlighted; technical aspects related to such a hyphenation are also discussed. The combination of heart-cutting MDGC with MS is much more established and is characterized by no specific technical difficulties (practically the same as for GC-MS instrumentation). For such a reason, particular focus will be devoted to the combination comprehensive MDGC-MS, and on aspects related to its evolution mainly after 2010.Pubblicazioni consigliate
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