Background • Although HIV-associated mortality has been greatly reduced by ART, the incidence of deaths due to non-communicable diseases (NCDs) remains high in persons with HIV (PWH) • More than half of the deaths observed in recent years among ART-experienced PLHIV are attributable to NCDs/comorbidities • NCDs include cardiovascular disease, hypertension, osteoporosis, kidney and liver failure, diabetes mellitus, cancer and other comorbidities such as central nervous system disorders. • Clinical decisions regarding whether to modify ART in the context of a HIV-RNA≤50 copies/mL may be guided by current ART and specific comorbidities
Selected comorbidities and the risk of ART switch in the context of HIV-RNA suppressed to ≤50 copies/mL
G. F. PELLICANOMembro del Collaboration Group
2023-01-01
Abstract
Background • Although HIV-associated mortality has been greatly reduced by ART, the incidence of deaths due to non-communicable diseases (NCDs) remains high in persons with HIV (PWH) • More than half of the deaths observed in recent years among ART-experienced PLHIV are attributable to NCDs/comorbidities • NCDs include cardiovascular disease, hypertension, osteoporosis, kidney and liver failure, diabetes mellitus, cancer and other comorbidities such as central nervous system disorders. • Clinical decisions regarding whether to modify ART in the context of a HIV-RNA≤50 copies/mL may be guided by current ART and specific comorbiditiesFile in questo prodotto:
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