Parkinson’s disease is a complex neurodegenerative disorder that primarily concerns movement, impacting the life quality of affected individuals. It is characterized by a gradual loss of certain brain cells responsible for producing dopamine, a neurotransmitter crucial for motor control. The main diagnosis is clinical, mainly based on motor symptoms. In the majority of instances, it is associated or preceded by non-motor manifestations, such as autonomic dysfunctions. Peripheral autonomic dysfunction is not always easy to detect. A valid method could be represented by the skin’s vasomotor response to cold stimuli. InfraRed Thermography represents a valuable tool for non-invasive assessment of Parkinson’s research, offering insights into thermoregulatory patterns associated with autonomic dysfunction. Early biomarkers of the disease can be obtained by changes in skin temperature, particularly in specific regions of interest, allowing for timely intervention and management. This study explores the feasibility of a preliminary measurement protocol for implementing thermography in Parkinson’s assessment, aiming to contribute to the advancement of non-invasive and objective diagnostic and monitoring tools. The protocol, crafted through a synthesis of pertinent findings, expert consensus, and adherence to ethical guidelines, is currently in the process of being submitted to an Ethics Committee.

Evaluation of Parkinson’s Disease by Means of InfraRed Thermography: Preliminary Results

Antonio Cannuli
;
Antonino Quattrocchi;Andrea Venuto;Roberto Montanini
2024-01-01

Abstract

Parkinson’s disease is a complex neurodegenerative disorder that primarily concerns movement, impacting the life quality of affected individuals. It is characterized by a gradual loss of certain brain cells responsible for producing dopamine, a neurotransmitter crucial for motor control. The main diagnosis is clinical, mainly based on motor symptoms. In the majority of instances, it is associated or preceded by non-motor manifestations, such as autonomic dysfunctions. Peripheral autonomic dysfunction is not always easy to detect. A valid method could be represented by the skin’s vasomotor response to cold stimuli. InfraRed Thermography represents a valuable tool for non-invasive assessment of Parkinson’s research, offering insights into thermoregulatory patterns associated with autonomic dysfunction. Early biomarkers of the disease can be obtained by changes in skin temperature, particularly in specific regions of interest, allowing for timely intervention and management. This study explores the feasibility of a preliminary measurement protocol for implementing thermography in Parkinson’s assessment, aiming to contribute to the advancement of non-invasive and objective diagnostic and monitoring tools. The protocol, crafted through a synthesis of pertinent findings, expert consensus, and adherence to ethical guidelines, is currently in the process of being submitted to an Ethics Committee.
2024
979-8-3503-0799-3
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/3303909
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