The thesis describes the development of innovative multifunctional nanomaterials based on cyclodextrins and carbohydrate polymers, with applications in drug delivery and environmental remediation. The work spans the synthesis and characterization of hybrid systems, such as hydrogels and supramolecular nanoassemblies, focusing on their ability to encapsulate active pharmaceutical ingredients or remove pollutants. The materials were designed following green chemistry principles and demonstrated biocompatibility, stimuli-responsiveness, and tunable release properties. Applications included photodynamic therapy for bacterial infections, anti-inflammatory treatments for osteoarthritis, and environmental sensing and clean-up. The results suggest that cyclodextrin-based platforms offer high versatility and potential for clinical and ecological applications.
Multifunctional materials based on cyclodextrins and carbohydrate polymers for controlled drug delivery and environmental applications
Burduja, Nina
2025-06-19
Abstract
The thesis describes the development of innovative multifunctional nanomaterials based on cyclodextrins and carbohydrate polymers, with applications in drug delivery and environmental remediation. The work spans the synthesis and characterization of hybrid systems, such as hydrogels and supramolecular nanoassemblies, focusing on their ability to encapsulate active pharmaceutical ingredients or remove pollutants. The materials were designed following green chemistry principles and demonstrated biocompatibility, stimuli-responsiveness, and tunable release properties. Applications included photodynamic therapy for bacterial infections, anti-inflammatory treatments for osteoarthritis, and environmental sensing and clean-up. The results suggest that cyclodextrin-based platforms offer high versatility and potential for clinical and ecological applications.Pubblicazioni consigliate
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