IRIS
PREVITI, Santo
 Distribuzione geografica
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Continente #
EU - Europa 3.268
NA - Nord America 1.940
AS - Asia 1.531
SA - Sud America 479
AF - Africa 51
OC - Oceania 4
Totale 7.273
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Nazione #
US - Stati Uniti d'America 1.876
RU - Federazione Russa 1.767
SG - Singapore 636
IT - Italia 417
BR - Brasile 403
CN - Cina 393
IE - Irlanda 300
HK - Hong Kong 211
SE - Svezia 180
PL - Polonia 178
VN - Vietnam 110
FR - Francia 108
DE - Germania 80
AT - Austria 71
GB - Regno Unito 53
IN - India 35
MX - Messico 32
BE - Belgio 31
AR - Argentina 26
FI - Finlandia 23
IQ - Iraq 23
CA - Canada 21
BD - Bangladesh 20
NL - Olanda 19
MA - Marocco 15
TR - Turchia 14
ID - Indonesia 13
CO - Colombia 12
UZ - Uzbekistan 12
PK - Pakistan 11
ZA - Sudafrica 11
EC - Ecuador 10
UA - Ucraina 9
VE - Venezuela 8
ES - Italia 7
PY - Paraguay 7
JP - Giappone 6
AE - Emirati Arabi Uniti 5
CL - Cile 5
DZ - Algeria 5
LT - Lituania 5
MY - Malesia 5
SA - Arabia Saudita 5
TN - Tunisia 5
AZ - Azerbaigian 4
CZ - Repubblica Ceca 4
KE - Kenya 4
PE - Perù 4
AU - Australia 3
GE - Georgia 3
KR - Corea 3
KW - Kuwait 3
LB - Libano 3
PH - Filippine 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
CH - Svizzera 2
CI - Costa d'Avorio 2
CR - Costa Rica 2
EG - Egitto 2
GR - Grecia 2
IR - Iran 2
JM - Giamaica 2
JO - Giordania 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LV - Lettonia 2
MD - Moldavia 2
NI - Nicaragua 2
PR - Porto Rico 2
RS - Serbia 2
SY - Repubblica araba siriana 2
BG - Bulgaria 1
BO - Bolivia 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GA - Gabon 1
HN - Honduras 1
IL - Israele 1
LY - Libia 1
MK - Macedonia 1
ML - Mali 1
MM - Myanmar 1
MN - Mongolia 1
MU - Mauritius 1
NZ - Nuova Zelanda 1
RO - Romania 1
SN - Senegal 1
SV - El Salvador 1
TZ - Tanzania 1
Totale 7.273
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Città #
Moscow 538
Singapore 352
Ashburn 331
Dublin 300
Chandler 251
Hong Kong 211
Warsaw 176
Messina 157
Nyköping 148
Beijing 123
Dallas 121
San Jose 108
Vienna 62
Princeton 50
Los Angeles 44
Ann Arbor 38
Lauterbourg 38
The Dalles 38
Ho Chi Minh City 35
Medford 34
Redondo Beach 33
Des Moines 31
Santa Clara 27
São Paulo 26
Guangzhou 24
Hanoi 23
New York 22
Frankfurt am Main 21
Aversa 19
Brussels 19
Jacksonville 19
Rome 17
Dearborn 16
Montpellier 16
Munich 16
Orem 16
Brasília 15
Houston 15
Cambridge 14
Council Bluffs 14
Modica 14
Buffalo 13
San Mateo 12
Tashkent 12
Tianjin 12
Amsterdam 11
Baghdad 11
Mexico City 11
Montreal 11
Belo Horizonte 10
Catania 10
Chennai 10
Rio de Janeiro 10
San Francisco 10
Shenzhen 10
Bari 9
Boston 9
Curitiba 9
Denver 9
Jinan 9
London 9
Brooklyn 8
Ixelles-Elsene 8
Stockholm 8
Atlanta 7
Bexley 7
Chicago 7
Helsinki 7
Phoenix 7
Siderno 7
Wilmington 7
Berlin 6
Campinas 6
Francavilla di Sicilia 6
Haikou 6
Medellín 6
Milan 6
Nuremberg 6
Querétaro 6
Shanghai 6
Shenyang 6
Taizhou 6
Tokyo 6
Biên Hòa 5
Boardman 5
Francofonte 5
Goiânia 5
Istanbul 5
Johannesburg 5
Manchester 5
Poplar 5
Porto Alegre 5
Portsmouth 5
Riposto 5
Seattle 5
Southampton 5
Ankara 4
Borghetto Santo Spirito 4
Brno 4
Cagliari 4
Totale 4.005
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Nome #
Design, synthesis and biological evaluation of novel inhibitors of rhodesain, cysteine protease of Trypanosoma brucei rhodesiense, as antitrypanosomal agents 343
Design, synthesis and biological evaluation of novel rhodesain inhibitors for the treatment of Human African Trypanosomiasis 191
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors 187
Design, synthesis and biological evaluation of novel dipeptide-like rhodesain inhibitors containing a conformationally constrained 3-bromoisoxazoline warhead 168
Design and NMR conformational analysis in solution of β5i-selective inhibitors of immunoproteasome 160
Development of novel 1,4-benzodiazepine-based Michael acceptors as antitrypanosomal agents 160
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors 158
Development of novel irreversible rhodesain inhibitors as antitrypanosomal agents. 153
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 151
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain 150
Development of novel amides as non covalent inhibitors of immunoproteasome 150
Development of novel benzodiazepine-based peptidomimetics as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 147
Evaluation of curcumin irreversibility 146
Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B 146
Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense 143
Discovery of novel peptidomimetics containing a benzodiazepine scaffold as inhibitors of rhodesain of Trypanosoma brucei rhodesiense 140
Drug combination studies of isoquinolinone AM12 with curcumin or quercetin: a new combination strategy to synergistically inhibit 20S proteasome 139
Development of novel 1,4-benzodiazepines as antitrypanosomal agents 136
Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei hodesiense 136
Immunoproteasome-selective inhibitors: a promising strategy to treat hematologic malignancies, autoimmune and inflammatory diseases 134
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 131
Design, synthesis and biological evaluation of potent rhodesain inhibitors as antitrypanosomal agents 130
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis 128
A second opportunity for the peptide-based analogues with γ-lactam at the P1 position: human cathepsin S inhibition 123
Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors 121
Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs) 121
Development of novel dipeptide-like rhodesain inhibitors containing the 3-bromoisoxazoline warhead in a constrained conformation 121
Development of Novel Benzodiazepine-Based Peptidomimetics as Inhibitors of Rhodesain from Trypanosoma brucei rhodesiense 121
The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis 117
Dipeptide nitrile CD34 with curcumin: a new improved combination strategy to synergistically inhibit rhodesain of Trypanosoma brucei rhodesiense 116
Development of novel peptidyl nitriles targeting rhodesain and falcipain-2 for the treatment of sleeping sickness and malaria 115
Development of peptidyl Michael acceptors for S3 pocket investigation of rhodesain, cysteine protease of Trypanosoma brucei rhodesiense 115
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of neglected tropical diseases (NTDs) 113
Development of reduced peptide bond pseudopeptide Michael acceptors for the treatment of Human African Trypanosomiasis 113
Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors 107
Monoclonal antibodies: the greatest resource to treat multiple myeloma 107
Peptidyl Vinyl Ketone Irreversible Inhibitors of Rhodesain: Modifications of the P2 Fragment 102
Neurotensin, a multi-faceted peptide 96
Drug synergism: studies of combination of RK-52 and curcumin against rhodesain of Trypanosoma brucei rhodesiense 95
Development of novel Michael acceptors targeting rhodesain as antitrypanosomal agents 94
Lead discovery of SARS-CoV-2 main protease inhibitors through covalent docking-based virtual screening 94
Drug combination studies of the dipeptide nitrile CD24 with curcumin: a new strategy to synergistically inhibit rhodesain of trypanosoma brucei rhodesiense 93
Drug combination studies of PS-1 and quercetin against rhodesain of Trypanosoma brucei rhodesiense 92
Development of novel peptide-based Michael acceptors targeting rhodesain for the treatment of human african trypanosomiasis 91
Falcipain-2 and Falcipain-3 inhibitors as promising antimalarial agents 91
Optimization of radiopharmaceuticals based on neurotensin[8-13] for NTS1-positive tumours imaging 89
Silicon-containing neurotensin analogues as radiopharmaceuticals for NTS1-positive tumors imaging 88
Design, synthesis, and in vitro characterization of proteolytically-stable opioid-neurotensin hybrid peptidomimetics 84
CAR-T cell therapy for prostate cancer: current advances and future perspectives 84
Identification of dual inhibitors targeting main protease (Mpro) and cathepsin L as potential anti-SARS-CoV‑2 agents 83
Structure-based design of melanocortin 4 receptor ligands based on the SHU-9119-hMC4R cocrystal structure 81
Optimized opioid-neurotensin multitarget peptides: from design to structure−activity relationship studies 80
Identification of constrained peptidomimetics carrying a Michael acceptor warhead as antitrypanosomal agents 77
Design and synthesis of opioid-neurotensin hybrid peptidomimetics: analgesics with reduced side effect profiles 77
Design, synthesis, and biological evaluation of the first radio-metalated neurotensin analogue targeting neurotensin receptor 2 76
The inhibition of NS2B/NS3 protease: a new therapeutic opportunity to treat Dengue and Zika virus infection 69
Design and synthesis of 68Ga-labeled peptide-based heterodimers for dual targeting of NTS1 and GRPR 68
Development of peptide-based SARS CoV-2 Mpro/hCatL dual inhibitors as antiviral agents 66
Dual inhibition of parasitic targets: a valuable strategy to treat malaria and neglected tropical diseases 61
Synthesis and Combination Studies of Novel Dipeptide Nitriles with Curcumin for a Potent Synergistic Action Against Rhodesain, Cysteine Protease of Trypanosoma brucei rhodesiense 56
The role of nutraceuticals in chemoprevention and their therapeutic effects when used in combination with synthetic drugs 52
Insightful backbone modifications preventing proteolytic degradation of neurotensin analogs improve NTS1-induced protective hypothermia 51
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The Role of Nutraceuticals in Age-Related Ocular Diseases 43
Metabolically stable neurotensin analogs exert potent and long-acting analgesia without hypothermia 34
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Opening the amino acid toolbox for peptide-based NTS2-selective ligands as promising lead compounds for pain management 24
Selected Nutraceuticals in Metabolic Syndrome: Molecular Mechanisms and Clinical Implications 22
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Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis 21
Rational design of NT-PSMA heterobivalent probes for prostate cancer theranostics 20
Hybrid synthetic approach and biological characterization of a branched heterodimer for overcoming prostate cancer heterogeneity 20
N-Terminal stabilization of radiolabeled neurotensin analogues for improved tumor uptake 16
Supplement: 37th European Peptide Symposium 14th International Peptide Symposium August 25–August 29, 2024 | Florence, Italy 15
Development of Novel Proline- and Pipecolic Acid-Based Allosteric Inhibitors of Dengue and Zika Virus NS2B/NS3 Protease 15
Inhibitors of proteases: a well-grounded strategy in drug development 15
Macrocycles and stapled-peptides in the fight against SARS-CoV-2: a review 5
Synthesis of New Asymmetrical Chalcones and Evaluation of Their Use in Combination with Curcumin Against Rhodesain of T. brucei rhodesiense 2
Totale 7.601
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Categoria #
all - tutte 23.546
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.546
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20217 0 0 0 0 0 0 0 0 0 0 0 7
2021/2022295 6 30 3 23 9 7 44 8 3 20 20 122
2022/2023981 62 94 42 77 55 103 47 78 364 4 48 7
2023/2024319 43 47 18 60 45 11 7 6 2 29 33 18
2024/20251.182 30 9 23 94 41 22 76 195 272 80 129 211
2025/20264.033 162 209 231 290 336 846 547 497 530 215 70 100
Totale 7.601