IRIS
IRACI, Nunzio
 Distribuzione geografica
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Continente #
NA - Nord America 7.541
EU - Europa 4.076
AS - Asia 2.324
SA - Sud America 892
AF - Africa 91
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 1
Totale 14.929
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Nazione #
US - Stati Uniti d'America 7.462
RU - Federazione Russa 2.393
SG - Singapore 1.049
BR - Brasile 774
CN - Cina 549
IE - Irlanda 453
SE - Svezia 350
HK - Hong Kong 275
VN - Vietnam 184
UA - Ucraina 179
IT - Italia 160
DE - Germania 158
FR - Francia 117
GB - Regno Unito 74
FI - Finlandia 73
IN - India 50
AR - Argentina 49
CA - Canada 35
MX - Messico 31
IQ - Iraq 23
PL - Polonia 23
TR - Turchia 21
ZA - Sudafrica 20
NL - Olanda 18
UZ - Uzbekistan 18
BD - Bangladesh 17
CO - Colombia 17
PK - Pakistan 17
CZ - Repubblica Ceca 16
EC - Ecuador 16
ID - Indonesia 16
MA - Marocco 16
ES - Italia 15
JP - Giappone 15
KE - Kenya 13
AT - Austria 12
VE - Venezuela 11
PH - Filippine 10
BE - Belgio 9
CI - Costa d'Avorio 9
JO - Giordania 9
AZ - Azerbaigian 7
CL - Cile 7
KG - Kirghizistan 7
KZ - Kazakistan 7
PS - Palestinian Territory 7
NP - Nepal 6
SA - Arabia Saudita 6
TN - Tunisia 6
UY - Uruguay 6
DZ - Algeria 5
BO - Bolivia 4
EG - Egitto 4
IL - Israele 4
IR - Iran 4
LV - Lettonia 4
NG - Nigeria 4
PE - Perù 4
BY - Bielorussia 3
GR - Grecia 3
HN - Honduras 3
PY - Paraguay 3
TH - Thailandia 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
CH - Svizzera 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GE - Georgia 2
KW - Kuwait 2
LK - Sri Lanka 2
LT - Lituania 2
LY - Libia 2
NO - Norvegia 2
OM - Oman 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
SY - Repubblica araba siriana 2
XK - ???statistics.table.value.countryCode.XK??? 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BF - Burkina Faso 1
BJ - Benin 1
CM - Camerun 1
EU - Europa 1
GM - Gambi 1
GT - Guatemala 1
GY - Guiana 1
HU - Ungheria 1
JM - Giamaica 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
MD - Moldavia 1
MM - Myanmar 1
MY - Malesia 1
Totale 14.918
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Città #
Dallas 4.596
Moscow 664
Ashburn 521
Singapore 495
Dublin 452
Chandler 330
Jacksonville 321
Hong Kong 272
Nyköping 262
Beijing 177
The Dalles 135
San Jose 112
Princeton 93
Los Angeles 84
Medford 81
Lauterbourg 70
Des Moines 65
Dearborn 61
São Paulo 60
Messina 59
Dong Ket 58
Cambridge 48
Munich 38
Buffalo 37
Guangzhou 37
Boardman 36
Hanoi 31
Santa Clara 30
New York 28
Ho Chi Minh City 27
Tianjin 27
Redondo Beach 23
Wilmington 22
Rio de Janeiro 19
Warsaw 19
Montreal 17
Ann Arbor 16
Belo Horizonte 16
Brasília 16
Curitiba 16
London 16
Orem 16
Tashkent 16
Chicago 15
Turku 15
Council Bluffs 14
Denver 13
Milan 13
Shanghai 13
Tokyo 13
Mexico City 12
Da Nang 11
Frankfurt am Main 11
Johannesburg 11
Pune 11
Brno 10
Brooklyn 10
Porto Alegre 10
Seattle 10
Abidjan 9
Amsterdam 9
Baghdad 9
Boston 9
Campinas 9
Chennai 9
Goiânia 9
Hebei 9
Houston 9
Jakarta 9
Nairobi 9
Nuremberg 9
Phoenix 9
Salvador 9
San Francisco 9
Toronto 9
Amman 8
Atlanta 8
Brussels 8
Lancaster 8
Poplar 8
Quito 8
Rome 8
Secaucus 8
Ankara 7
Bishkek 7
Hyderabad 7
Jinan 7
Nanjing 7
Shenzhen 7
Stockholm 7
Taizhou 7
Washington 7
Baku 6
Columbus 6
Guarulhos 6
Lappeenranta 6
Manchester 6
Ningbo 6
Oviedo 6
Santo André 6
Totale 10.030
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.607
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 178
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 178
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 178
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 175
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 171
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 170
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 164
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 161
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 156
A comprehensive structural overview of p38α MAPK in complex with type I inhibitors 154
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 138
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 135
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 135
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 134
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 132
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model 132
Progettazione, Sintesi e SAR di analoghi 1,3-diidro-benzimidazoloni come nuovi agenti anti-HIV 131
Anticancer activity and morphological analysis of Pt(II) complexes: Their DFT approach, docking simulation, and ADME-Tox profiling 130
Nuovi Antagonisti Non-Competitivi Del Recettore NMDA/NR2b: Design e Sintesi” 129
INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS 128
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B palm site i inhibitors case study 126
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 126
Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 124
Allosteric inhibition of the hepatitis C virus NS5B polymerase: In silico strategies for drug discovery and development 124
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 123
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 117
IκB kinase ε targets interferon regulatory factor 1 in activated T lymphocytes 117
null 111
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents 109
Design and Synthesis of NR2B Subtype-Selective Antagonist 108
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 107
Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 tat-mediated transcription activity 104
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 103
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 103
NCp7: targeting a multitask protein for next-generation anti-HIV drug development part 2. Noncovalent inhibitors and nucleic acid binders 102
Identificazione di Nuovi Inibitori Non-Nucleosidicidella Trascrittasi Inversa dell' HIV-1 Mediante Tecniche di Virtual screening 99
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 99
Characterization of bicalutamide/cyclodextrin inclusion complexes and anticancer activity evaluation 98
Pharmacophore Modeling, Docking Experiments And Discovery Of New Hiv-1 NNRTIs 98
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 98
Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations 98
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity 97
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 96
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 95
NCp7: targeting a multitasking protein for next-generation anti-HIV drug development part 1: covalent inhibitors 95
null 93
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 92
In Silico Methods for the Discovery of Kv7.2/7.3 Channels Modulators: A Comprehensive Review 91
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 91
Pyrazolo[4,3-c ][1,2]benzothiazines 5,5-dioxide: A promising new class of staphylococcus aureus NorA efflux pump inhibitors 91
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 91
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 89
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1 88
Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network 88
Direct Access to α,β‐Unsaturated γ‐Lactams via Palladium‐Catalysed Carbonylation of Propargylic Ureas 87
Investigating the Cytotoxicity of Ru(II) Polypyridyl Complexes by Changing the Electronic Structure of Salicylaldehyde Ligands 87
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non –Nucleoside riverse Transcriptase Inhibitors 87
Pharmacological agents targeting the cellular prion protein 87
KCNT1 Channel Blockers: A Medicinal Chemistry Perspective 86
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside riverse transcriptase inhibitors 86
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 86
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches 86
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 86
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 86
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 85
Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions 83
Tumor Targeting by Peptide-Decorated Gold Nanoparticles 83
From small to powerful: The fragments universe and its 'chem-appeal' 83
Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin 83
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 82
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1; , 82
Molecular modeling and synthesis for the discovery of HIV-1 IN-LEDGF/P75 interaction inhibitors. 82
Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors 82
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 81
New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site i inhibitors 81
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening 81
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification 81
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 80
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors 79
Nuovo modello farmacoforico per inibitori dell'Integrasi dell'HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 79
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 79
P38α MAPK and Type I inhibitors: Binding site analysis and use of target ensembles in virtual screening 78
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: A basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy 78
A second opportunity for the peptide-based analogues with γ-lactam at the P1 position: human cathepsin S inhibition 77
Structural features and antiproliferative activity of Pd(II) complexes with halogenated ligands: a comparative study between Schiff base and reduced Schiff base complexes 76
Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs 76
β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing 75
Re-evolution of the 2-phenylquinolines: Ligand-based design, synthesis, and biological evaluation of a potent new class of staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance 75
The Versatile Nature of the 6-Aminoquinolone Scaffold: Identification of Submicromolar Hepatitis C Virus NS5B Inhibitors 71
In silico studies of anticancer Pt(II) and Zn(II) complexes: Investigation of their binding mode to different G-quadruplex DNA topologies 70
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 69
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication 67
Synergistic Combination of Citrus Flavanones as Strong Antioxidant and COX-Inhibitor Agent 67
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells 66
Randomly methylated β-cyclodextrin improves water – solubility, cellular protection and mucosa permeability of idebenone 65
Recent Advances in the Development of Immunoproteasome Inhibitors as Anti-Cancer Agents: The Past 5 Years 55
Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study 54
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy 48
Tn5 transposase as a useful platform to simulate HIV-1 integrase inhibitor binding mode 47
Totale 14.571
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Categoria #
all - tutte 39.696
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.696
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021138 0 0 0 0 0 0 0 0 0 44 20 74
2021/2022446 5 53 10 13 33 7 32 19 10 5 48 211
2022/20231.371 126 107 68 103 84 156 47 55 556 6 54 9
2023/2024309 43 57 21 28 33 44 6 15 4 18 8 32
2024/20252.068 30 17 56 95 115 59 91 494 529 125 134 323
2025/20269.777 254 1.616 3.392 454 482 1.257 687 745 660 230 0 0
Totale 15.100