IRIS
IRACI, Nunzio
 Distribuzione geografica
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Continente #
NA - Nord America 1.555
EU - Europa 1.247
AS - Asia 496
AF - Africa 6
SA - Sud America 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 3.307
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Nazione #
US - Stati Uniti d'America 1.550
IE - Irlanda 426
SE - Svezia 330
SG - Singapore 242
CN - Cina 168
UA - Ucraina 156
DE - Germania 105
IT - Italia 98
VN - Vietnam 58
FI - Finlandia 47
GB - Regno Unito 23
IN - India 17
CZ - Repubblica Ceca 13
RU - Federazione Russa 13
BE - Belgio 8
PL - Polonia 8
AT - Austria 5
CA - Canada 5
NL - Olanda 5
FR - Francia 4
ID - Indonesia 3
IR - Iran 2
LV - Lettonia 2
NG - Nigeria 2
TN - Tunisia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BO - Bolivia 1
CH - Svizzera 1
CL - Cile 1
EG - Egitto 1
ES - Italia 1
HK - Hong Kong 1
JP - Giappone 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
PH - Filippine 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
ZA - Sudafrica 1
Totale 3.307
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Città #
Dublin 425
Chandler 315
Jacksonville 292
Nyköping 251
Singapore 204
Princeton 89
Medford 77
Ashburn 64
Beijing 64
Des Moines 63
Dearborn 58
Dong Ket 58
Cambridge 44
Messina 37
Boardman 32
Wilmington 18
Munich 16
Los Angeles 14
Ann Arbor 12
Pune 11
Brno 9
Hebei 9
Santa Clara 9
Brussels 8
Warsaw 8
Milan 7
Nanjing 7
Taizhou 7
Washington 7
Jinan 6
Shenyang 6
Tianjin 6
Woodbridge 6
Catania 5
Hangzhou 5
Hyderabad 5
Lancaster 5
Ningbo 5
Guangzhou 4
Kunming 4
Olomouc 4
Rome 4
Saint Petersburg 4
Seattle 4
Vienna 4
West Jordan 4
Zhengzhou 4
Amsterdam 3
Brugherio 3
Chicago 3
Como 3
Falls Church 3
Fuzhou 3
Helsinki 3
Irpin 3
Jakarta 3
Mcallen 3
San Mateo 3
Siena 3
Taiyuan 3
Ardabil 2
Brooklyn 2
Changsha 2
Dongguan 2
Haikou 2
Hefei 2
Jiaxing 2
London 2
Monmouth Junction 2
Montréal 2
Mountain View 2
Nanchang 2
New York 2
Pagani 2
Perugia 2
San Gregorio di Catania 2
Shanghai 2
Springfield 2
Tunis 2
Agerola 1
Albuquerque 1
Augusta 1
Bishkek 1
Bratislava 1
Cairo 1
Central 1
Delhi 1
Durham 1
Edmonton 1
Frigento 1
Geneva 1
Irving 1
Istanbul 1
Jianning 1
Kemerovo 1
Kildare 1
La Paz 1
Lappeenranta 1
Leawood 1
Luleå 1
Totale 2.398
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 202
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 64
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 62
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 61
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 61
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 59
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 56
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 56
Progettazione, Sintesi e SAR di analoghi 1,3-diidro-benzimidazoloni come nuovi agenti anti-HIV 55
INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS 53
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 53
Pharmacophore Modeling, Docking Experiments And Discovery Of New Hiv-1 NNRTIs 52
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 52
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 52
Identificazione di Nuovi Inibitori Non-Nucleosidicidella Trascrittasi Inversa dell' HIV-1 Mediante Tecniche di Virtual screening 51
Design and Synthesis of NR2B Subtype-Selective Antagonist 51
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 51
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 50
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 50
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 50
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 48
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 47
Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 45
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 45
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 44
A comprehensive structural overview of p38α MAPK in complex with type I inhibitors 42
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 41
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1 40
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 38
Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations 38
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 38
Nuovo modello farmacoforico per inibitori dell'Integrasi dell'HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 37
IκB kinase ε targets interferon regulatory factor 1 in activated T lymphocytes 37
Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network 37
Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 tat-mediated transcription activity 36
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 34
Allosteric inhibition of the hepatitis C virus NS5B polymerase: In silico strategies for drug discovery and development 34
P38α MAPK and Type I inhibitors: Binding site analysis and use of target ensembles in virtual screening 33
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 33
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 32
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity 32
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non –Nucleoside riverse Transcriptase Inhibitors 31
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Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 31
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B palm site i inhibitors case study 31
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 30
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1; , 30
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches 30
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 30
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Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: A basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy 29
NCp7: targeting a multitasking protein for next-generation anti-HIV drug development part 1: covalent inhibitors 29
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 29
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β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing 28
Pyrazolo[4,3-c ][1,2]benzothiazines 5,5-dioxide: A promising new class of staphylococcus aureus NorA efflux pump inhibitors 28
NCp7: targeting a multitask protein for next-generation anti-HIV drug development part 2. Noncovalent inhibitors and nucleic acid binders 28
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Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 26
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 26
Pharmacological agents targeting the cellular prion protein 26
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Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 23
Tumor Targeting by Peptide-Decorated Gold Nanoparticles 23
New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site i inhibitors 23
From small to powerful: The fragments universe and its 'chem-appeal' 23
Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors 23
Tn5 transposase as a useful platform to simulate HIV-1 integrase inhibitor binding mode 22
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 22
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 22
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model 22
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening 22
Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study 21
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside riverse transcriptase inhibitors 20
Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions 20
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors 20
Re-evolution of the 2-phenylquinolines: Ligand-based design, synthesis, and biological evaluation of a potent new class of staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance 19
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 18
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 17
Bicalutamide Anticancer Activity Enhancement by Formulation of Soluble Inclusion Complexes with Cyclodextrins 16
Characterization of bicalutamide/cyclodextrin inclusion complexes and anticancer activity evaluation 15
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication 15
Extracellular Vesicles as Novel Diagnostic and Prognostic Biomarkers for Parkinson's Disease 14
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 14
Induced-Fit Docking Approach Provides Insight into the Binding Mode and Mechanism of Action of HIV-1 Integrase Inhibitors 13
The Versatile Nature of the 6-Aminoquinolone Scaffold: Identification of Submicromolar Hepatitis C Virus NS5B Inhibitors 13
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents 12
Structural features and antiproliferative activity of Pd(II) complexes with halogenated ligands: a comparative study between Schiff base and reduced Schiff base complexes 11
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells 11
Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin 11
Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs 10
SIRT5 rs12216101 T>G variant is associated with liver damage and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease 9
Synergistic Combination of Citrus Flavanones as Strong Antioxidant and COX-Inhibitor Agent 9
Totale 3.369
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Categoria #
all - tutte 17.958
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.958
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020213 0 0 0 0 0 0 57 49 6 39 61 1
2020/2021394 44 0 51 11 2 42 3 86 22 41 18 74
2021/2022424 5 52 9 13 31 7 26 17 10 5 46 203
2022/20231.306 120 103 66 96 77 152 45 54 525 6 55 7
2023/2024299 41 56 21 28 33 43 6 14 4 16 8 29
2024/2025387 28 16 62 94 114 67 6 0 0 0 0 0
Totale 3.435