IRIS
IRACI, Nunzio
 Distribuzione geografica
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Continente #
NA - Nord America 7.730
EU - Europa 4.085
AS - Asia 2.353
SA - Sud America 893
AF - Africa 91
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 1
Totale 15.157
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Nazione #
US - Stati Uniti d'America 7.638
RU - Federazione Russa 2.393
SG - Singapore 1.055
BR - Brasile 775
CN - Cina 568
IE - Irlanda 453
SE - Svezia 350
HK - Hong Kong 276
VN - Vietnam 185
UA - Ucraina 179
IT - Italia 165
DE - Germania 158
FR - Francia 118
GB - Regno Unito 74
FI - Finlandia 73
IN - India 50
AR - Argentina 49
CA - Canada 42
MX - Messico 32
IQ - Iraq 23
PL - Polonia 23
TR - Turchia 21
ZA - Sudafrica 20
NL - Olanda 19
UZ - Uzbekistan 18
BD - Bangladesh 17
CO - Colombia 17
PK - Pakistan 17
CZ - Repubblica Ceca 16
EC - Ecuador 16
ES - Italia 16
ID - Indonesia 16
JP - Giappone 16
MA - Marocco 16
KE - Kenya 13
AT - Austria 12
VE - Venezuela 11
PH - Filippine 10
BE - Belgio 9
CI - Costa d'Avorio 9
JO - Giordania 9
AZ - Azerbaigian 7
CL - Cile 7
KG - Kirghizistan 7
KZ - Kazakistan 7
PS - Palestinian Territory 7
NP - Nepal 6
SA - Arabia Saudita 6
TN - Tunisia 6
UY - Uruguay 6
DZ - Algeria 5
BO - Bolivia 4
EG - Egitto 4
IL - Israele 4
IR - Iran 4
LV - Lettonia 4
NG - Nigeria 4
PE - Perù 4
AE - Emirati Arabi Uniti 3
BY - Bielorussia 3
CR - Costa Rica 3
GR - Grecia 3
HN - Honduras 3
PY - Paraguay 3
TH - Thailandia 3
AL - Albania 2
CH - Svizzera 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
GE - Georgia 2
JM - Giamaica 2
KW - Kuwait 2
LK - Sri Lanka 2
LT - Lituania 2
LY - Libia 2
NI - Nicaragua 2
NO - Norvegia 2
OM - Oman 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
SN - Senegal 2
SY - Repubblica araba siriana 2
XK - ???statistics.table.value.countryCode.XK??? 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BF - Burkina Faso 1
BJ - Benin 1
BZ - Belize 1
CM - Camerun 1
EU - Europa 1
GM - Gambi 1
GT - Guatemala 1
GY - Guiana 1
HU - Ungheria 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
MD - Moldavia 1
Totale 15.143
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Città #
Dallas 4.598
Moscow 664
Ashburn 545
Singapore 497
Dublin 452
Chandler 330
Jacksonville 321
Hong Kong 273
Nyköping 262
Beijing 177
San Jose 174
The Dalles 137
Princeton 93
Los Angeles 87
Medford 81
Lauterbourg 70
Des Moines 66
Dearborn 61
São Paulo 60
Messina 59
Dong Ket 58
Cambridge 48
Buffalo 38
Munich 38
Guangzhou 37
Santa Clara 37
Boardman 36
Council Bluffs 31
Hanoi 31
New York 29
Ho Chi Minh City 28
Tianjin 27
Redondo Beach 23
Wilmington 22
Montreal 21
Rio de Janeiro 19
Warsaw 19
Chicago 18
Orem 17
Ann Arbor 16
Belo Horizonte 16
Brasília 16
Curitiba 16
London 16
Tashkent 16
Turku 15
Denver 13
Milan 13
Shanghai 13
Tokyo 13
Brooklyn 12
Mexico City 12
Da Nang 11
Frankfurt am Main 11
Johannesburg 11
Pune 11
Brno 10
Porto Alegre 10
San Francisco 10
Seattle 10
Abidjan 9
Amsterdam 9
Atlanta 9
Baghdad 9
Boston 9
Campinas 9
Chennai 9
Goiânia 9
Hebei 9
Houston 9
Jakarta 9
Lancaster 9
Nairobi 9
Nuremberg 9
Phoenix 9
Salvador 9
Toronto 9
Amman 8
Brussels 8
Poplar 8
Quito 8
Rome 8
Secaucus 8
Washington 8
Ankara 7
Bishkek 7
Hyderabad 7
Jinan 7
Nanjing 7
Shenzhen 7
Stockholm 7
Taizhou 7
Baku 6
Columbus 6
Guarulhos 6
Lappeenranta 6
Manchester 6
Ningbo 6
Oviedo 6
Santo André 6
Totale 10.168
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.608
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 183
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 181
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 178
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 176
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 175
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 171
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 165
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 161
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 157
A comprehensive structural overview of p38α MAPK in complex with type I inhibitors 156
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 139
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 137
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 136
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 135
Anticancer activity and morphological analysis of Pt(II) complexes: Their DFT approach, docking simulation, and ADME-Tox profiling 133
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 133
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model 133
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 132
Progettazione, Sintesi e SAR di analoghi 1,3-diidro-benzimidazoloni come nuovi agenti anti-HIV 131
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 131
Nuovi Antagonisti Non-Competitivi Del Recettore NMDA/NR2b: Design e Sintesi” 130
INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS 129
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B palm site i inhibitors case study 129
Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 128
Allosteric inhibition of the hepatitis C virus NS5B polymerase: In silico strategies for drug discovery and development 125
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 118
IκB kinase ε targets interferon regulatory factor 1 in activated T lymphocytes 118
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents 112
null 111
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 109
Design and Synthesis of NR2B Subtype-Selective Antagonist 108
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 106
Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 tat-mediated transcription activity 106
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 103
NCp7: targeting a multitask protein for next-generation anti-HIV drug development part 2. Noncovalent inhibitors and nucleic acid binders 102
Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations 101
Characterization of bicalutamide/cyclodextrin inclusion complexes and anticancer activity evaluation 100
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 100
Identificazione di Nuovi Inibitori Non-Nucleosidicidella Trascrittasi Inversa dell' HIV-1 Mediante Tecniche di Virtual screening 99
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 99
Pharmacophore Modeling, Docking Experiments And Discovery Of New Hiv-1 NNRTIs 98
NCp7: targeting a multitasking protein for next-generation anti-HIV drug development part 1: covalent inhibitors 98
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity 98
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 96
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 96
Direct Access to α,β‐Unsaturated γ‐Lactams via Palladium‐Catalysed Carbonylation of Propargylic Ureas 95
In Silico Methods for the Discovery of Kv7.2/7.3 Channels Modulators: A Comprehensive Review 95
Investigating the Cytotoxicity of Ru(II) Polypyridyl Complexes by Changing the Electronic Structure of Salicylaldehyde Ligands 94
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 94
null 93
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 92
Pyrazolo[4,3-c ][1,2]benzothiazines 5,5-dioxide: A promising new class of staphylococcus aureus NorA efflux pump inhibitors 92
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 91
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 91
KCNT1 Channel Blockers: A Medicinal Chemistry Perspective 90
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 89
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside riverse transcriptase inhibitors 88
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 88
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1 88
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 88
Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network 88
Pharmacological agents targeting the cellular prion protein 88
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 87
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches 87
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non –Nucleoside riverse Transcriptase Inhibitors 87
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification 86
Tumor Targeting by Peptide-Decorated Gold Nanoparticles 85
Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors 85
Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions 84
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 84
From small to powerful: The fragments universe and its 'chem-appeal' 84
Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin 84
Structural features and antiproliferative activity of Pd(II) complexes with halogenated ligands: a comparative study between Schiff base and reduced Schiff base complexes 83
Molecular modeling and synthesis for the discovery of HIV-1 IN-LEDGF/P75 interaction inhibitors. 83
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors 82
Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs 82
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 82
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1; , 82
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 82
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 82
New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site i inhibitors 81
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening 81
A second opportunity for the peptide-based analogues with γ-lactam at the P1 position: human cathepsin S inhibition 81
Nuovo modello farmacoforico per inibitori dell'Integrasi dell'HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 79
P38α MAPK and Type I inhibitors: Binding site analysis and use of target ensembles in virtual screening 79
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: A basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy 78
Re-evolution of the 2-phenylquinolines: Ligand-based design, synthesis, and biological evaluation of a potent new class of staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance 77
In silico studies of anticancer Pt(II) and Zn(II) complexes: Investigation of their binding mode to different G-quadruplex DNA topologies 76
β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing 75
The Versatile Nature of the 6-Aminoquinolone Scaffold: Identification of Submicromolar Hepatitis C Virus NS5B Inhibitors 73
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells 72
Randomly methylated β-cyclodextrin improves water – solubility, cellular protection and mucosa permeability of idebenone 70
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 69
Synergistic Combination of Citrus Flavanones as Strong Antioxidant and COX-Inhibitor Agent 68
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication 67
Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study 60
Recent Advances in the Development of Immunoproteasome Inhibitors as Anti-Cancer Agents: The Past 5 Years 58
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy 55
Tn5 transposase as a useful platform to simulate HIV-1 integrase inhibitor binding mode 48
Totale 14.772
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Categoria #
all - tutte 42.031
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.031
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202174 0 0 0 0 0 0 0 0 0 0 0 74
2021/2022446 5 53 10 13 33 7 32 19 10 5 48 211
2022/20231.371 126 107 68 103 84 156 47 55 556 6 54 9
2023/2024309 43 57 21 28 33 44 6 15 4 18 8 32
2024/20252.068 30 17 56 95 115 59 91 494 529 125 134 323
2025/202610.005 254 1.616 3.392 454 482 1.257 687 745 660 276 111 71
Totale 15.328