IRIS
IRACI, Nunzio
 Distribuzione geografica
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Continente #
NA - Nord America 7.016
AS - Asia 1.813
EU - Europa 1.620
SA - Sud America 823
AF - Africa 66
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 1
Totale 11.343
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Nazione #
US - Stati Uniti d'America 6.951
SG - Singapore 849
BR - Brasile 737
IE - Irlanda 445
CN - Cina 370
SE - Svezia 348
HK - Hong Kong 266
UA - Ucraina 175
VN - Vietnam 156
DE - Germania 151
IT - Italia 144
RU - Federazione Russa 87
FI - Finlandia 71
GB - Regno Unito 63
AR - Argentina 36
FR - Francia 32
CA - Canada 29
IN - India 29
MX - Messico 25
PL - Polonia 21
CO - Colombia 16
CZ - Repubblica Ceca 16
ZA - Sudafrica 16
TR - Turchia 15
UZ - Uzbekistan 15
AT - Austria 12
BD - Bangladesh 12
ID - Indonesia 12
IQ - Iraq 12
NL - Olanda 12
ES - Italia 11
MA - Marocco 11
KE - Kenya 10
PK - Pakistan 10
EC - Ecuador 9
JP - Giappone 9
BE - Belgio 8
CI - Costa d'Avorio 8
VE - Venezuela 8
KG - Kirghizistan 7
KZ - Kazakistan 7
JO - Giordania 6
UY - Uruguay 6
AZ - Azerbaigian 5
DZ - Algeria 5
NP - Nepal 5
CL - Cile 4
EG - Egitto 4
LV - Lettonia 4
PS - Palestinian Territory 4
TN - Tunisia 4
BO - Bolivia 3
BY - Bielorussia 3
HN - Honduras 3
IL - Israele 3
IR - Iran 3
NG - Nigeria 3
PH - Filippine 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
CH - Svizzera 2
DO - Repubblica Dominicana 2
GR - Grecia 2
LT - Lituania 2
NO - Norvegia 2
OM - Oman 2
PE - Perù 2
PY - Paraguay 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
XK - ???statistics.table.value.countryCode.XK??? 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
CM - Camerun 1
CR - Costa Rica 1
EU - Europa 1
GE - Georgia 1
GM - Gambi 1
GT - Guatemala 1
HU - Ungheria 1
JM - Giamaica 1
KH - Cambogia 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LK - Sri Lanka 1
MD - Moldavia 1
MZ - Mozambico 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PA - Panama 1
QA - Qatar 1
SA - Arabia Saudita 1
SV - El Salvador 1
TH - Thailandia 1
TJ - Tagikistan 1
Totale 11.343
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Città #
Dallas 4.588
Dublin 444
Singapore 342
Chandler 327
Jacksonville 313
Ashburn 306
Hong Kong 263
Nyköping 260
Beijing 173
Princeton 92
The Dalles 83
Medford 80
Los Angeles 77
Des Moines 65
Dearborn 61
Dong Ket 58
São Paulo 57
Messina 56
Cambridge 47
Buffalo 37
Munich 37
Boardman 34
Hanoi 25
Ho Chi Minh City 25
Santa Clara 25
New York 24
Redondo Beach 23
Moscow 19
Wilmington 18
Warsaw 17
Brasília 16
Curitiba 16
London 16
Rio de Janeiro 16
Ann Arbor 15
Belo Horizonte 15
Turku 15
Chicago 14
Tianjin 14
Montreal 13
Tashkent 13
Milan 12
Pune 11
Brno 10
Brooklyn 10
Denver 10
Mexico City 10
Seattle 10
Boston 9
Hebei 9
Jakarta 9
Nuremberg 9
Phoenix 9
Salvador 9
Abidjan 8
Brussels 8
Campinas 8
Houston 8
Johannesburg 8
Lancaster 8
Porto Alegre 8
Secaucus 8
Tokyo 8
Bishkek 7
Frankfurt am Main 7
Goiânia 7
Hyderabad 7
Jinan 7
Nanjing 7
Rome 7
San Francisco 7
Stockholm 7
Taizhou 7
Toronto 7
Washington 7
Ankara 6
Chennai 6
Columbus 6
Guarulhos 6
Nairobi 6
Poplar 6
Santo André 6
Shenyang 6
Vienna 6
Vitória 6
Woodbridge 6
Amman 5
Atlanta 5
Baghdad 5
Baku 5
Belford Roxo 5
Caxias do Sul 5
Contagem 5
Council Bluffs 5
Fortaleza 5
Guangzhou 5
Hangzhou 5
Helsinki 5
Lappeenranta 5
Montevideo 5
Totale 8.558
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Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 4.544
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 132
3D Pharmacophore model and synthesys of NMDA receptor subunit NR2B antagonists 127
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 123
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 122
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 117
Nuovi Antagonisti Non-Competitivi Del Recettore NMDA/NR2b: Design e Sintesi” 110
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 107
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 103
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 101
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 100
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 97
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 95
A comprehensive structural overview of p38α MAPK in complex with type I inhibitors 95
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 92
Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study 89
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 89
Progettazione, Sintesi e SAR di analoghi 1,3-diidro-benzimidazoloni come nuovi agenti anti-HIV 89
Design and Synthesis of NR2B Subtype-Selective Antagonist 86
INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS 85
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 84
Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 83
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 81
Allosteric inhibition of the hepatitis C virus NS5B polymerase: In silico strategies for drug discovery and development 81
Pharmacophore Modeling, Docking Experiments And Discovery Of New Hiv-1 NNRTIs 79
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 79
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model 79
Identificazione di Nuovi Inibitori Non-Nucleosidicidella Trascrittasi Inversa dell' HIV-1 Mediante Tecniche di Virtual screening 78
IκB kinase ε targets interferon regulatory factor 1 in activated T lymphocytes 78
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 78
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 77
Bicalutamide Anticancer Activity Enhancement by Formulation of Soluble Inclusion Complexes with Cyclodextrins 75
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 73
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 73
NCp7: targeting a multitask protein for next-generation anti-HIV drug development part 2. Noncovalent inhibitors and nucleic acid binders 73
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 69
Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations 69
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1 68
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B palm site i inhibitors case study 68
Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network 68
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 66
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 66
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 66
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 65
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 65
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity 65
Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 tat-mediated transcription activity 65
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non –Nucleoside riverse Transcriptase Inhibitors 64
Anticancer activity and morphological analysis of Pt(II) complexes: Their DFT approach, docking simulation, and ADME-Tox profiling 63
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 63
NCp7: targeting a multitasking protein for next-generation anti-HIV drug development part 1: covalent inhibitors 62
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches 61
Molecular modeling and synthesis for the discovery of HIV-1 IN-LEDGF/P75 interaction inhibitors. 61
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 60
Nuovo modello farmacoforico per inibitori dell'Integrasi dell'HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 59
β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing 59
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 59
Pyrazolo[4,3-c ][1,2]benzothiazines 5,5-dioxide: A promising new class of staphylococcus aureus NorA efflux pump inhibitors 59
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 59
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 59
Characterization of bicalutamide/cyclodextrin inclusion complexes and anticancer activity evaluation 58
Pharmacological agents targeting the cellular prion protein 58
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents 58
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 57
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1; , 56
Tumor Targeting by Peptide-Decorated Gold Nanoparticles 56
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening 56
Investigating the Cytotoxicity of Ru(II) Polypyridyl Complexes by Changing the Electronic Structure of Salicylaldehyde Ligands 55
P38α MAPK and Type I inhibitors: Binding site analysis and use of target ensembles in virtual screening 55
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: A basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy 55
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 54
Re-evolution of the 2-phenylquinolines: Ligand-based design, synthesis, and biological evaluation of a potent new class of staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance 54
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 54
New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site i inhibitors 54
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 52
Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs 52
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside riverse transcriptase inhibitors 51
From small to powerful: The fragments universe and its 'chem-appeal' 51
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors 50
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification 50
In Silico Methods for the Discovery of Kv7.2/7.3 Channels Modulators: A Comprehensive Review 49
Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors 49
KCNT1 Channel Blockers: A Medicinal Chemistry Perspective 48
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication 48
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells 47
In silico studies of anticancer Pt(II) and Zn(II) complexes: Investigation of their binding mode to different G-quadruplex DNA topologies 47
Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions 46
The Versatile Nature of the 6-Aminoquinolone Scaffold: Identification of Submicromolar Hepatitis C Virus NS5B Inhibitors 46
Direct Access to α,β‐Unsaturated γ‐Lactams via Palladium‐Catalysed Carbonylation of Propargylic Ureas 45
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 45
Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin 45
Structural features and antiproliferative activity of Pd(II) complexes with halogenated ligands: a comparative study between Schiff base and reduced Schiff base complexes 42
Synergistic Combination of Citrus Flavanones as Strong Antioxidant and COX-Inhibitor Agent 42
Tn5 transposase as a useful platform to simulate HIV-1 integrase inhibitor binding mode 37
Randomly methylated β-cyclodextrin improves water – solubility, cellular protection and mucosa permeability of idebenone 34
Recent Advances in the Development of Immunoproteasome Inhibitors as Anti-Cancer Agents: The Past 5 Years 33
Study of Host-Guest Interaction and In Vitro Neuroprotective Potential of Cinnamic Acid/Randomly Methylated β-Cyclodextrin Inclusion Complex 33
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Totale 11.173
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Categoria #
all - tutte 33.999
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.999
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021297 0 0 0 0 0 45 3 89 23 43 20 74
2021/2022438 5 53 9 13 33 7 28 18 10 5 48 209
2022/20231.354 125 107 68 101 81 156 46 54 549 6 54 7
2023/2024308 42 57 21 28 33 44 6 15 4 18 8 32
2024/20252.056 30 17 56 94 115 58 91 493 521 125 133 323
2025/20266.236 253 1.614 3.388 453 480 48 0 0 0 0 0 0
Totale 11.505