IRIS
IRACI, Nunzio
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 1.488
EU - Europa 1.188
AS - Asia 220
AF - Africa 2
Continente sconosciuto - Info sul continente non disponibili 1
SA - Sud America 1
Totale 2.900
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 1.483
IE - Irlanda 428
SE - Svezia 330
UA - Ucraina 152
CN - Cina 144
DE - Germania 89
IT - Italia 82
VN - Vietnam 58
FI - Finlandia 45
GB - Regno Unito 25
IN - India 11
RU - Federazione Russa 11
BE - Belgio 8
PL - Polonia 7
CA - Canada 5
AT - Austria 4
FR - Francia 2
IR - Iran 2
NG - Nigeria 2
A2 - ???statistics.table.value.countryCode.A2??? 1
CH - Svizzera 1
CL - Cile 1
CZ - Repubblica Ceca 1
HK - Hong Kong 1
JP - Giappone 1
LV - Lettonia 1
NL - Olanda 1
PH - Filippine 1
RO - Romania 1
SG - Singapore 1
TR - Turchia 1
Totale 2.900
Salva come PNG Salva come JPEG
Città #
Dublin 427
Chandler 315
Jacksonville 292
Nyköping 251
Princeton 89
Medford 77
Ashburn 64
Beijing 64
Des Moines 63
Dearborn 58
Dong Ket 58
Cambridge 44
Boardman 32
Messina 27
Wilmington 18
Ann Arbor 12
Pune 11
Hebei 9
Brussels 8
Taizhou 7
Warsaw 7
Washington 7
Jinan 6
Nanjing 6
Shenyang 6
Tianjin 6
Woodbridge 6
Hangzhou 5
Lancaster 5
Milan 5
Ningbo 5
Kunming 4
Saint Petersburg 4
Seattle 4
Vienna 4
West Jordan 4
Zhengzhou 4
Brugherio 3
Catania 3
Como 3
Falls Church 3
Mcallen 3
Rome 3
San Mateo 3
Siena 3
Taiyuan 3
Ardabil 2
Brooklyn 2
Castel San Giorgio 2
Changsha 2
Chicago 2
Dongguan 2
Fuzhou 2
Haikou 2
Hefei 2
Helsinki 2
Jiaxing 2
Leyton 2
London 2
Monmouth Junction 2
Montréal 2
Mountain View 2
Munich 2
Nanchang 2
Naples 2
New York 2
Pagani 2
Perugia 2
Agerola 1
Albuquerque 1
Augusta 1
Brno 1
Central 1
Durham 1
Edmonton 1
Frigento 1
Geneva 1
Irving 1
Istanbul 1
Kemerovo 1
Kildare 1
Leawood 1
Luleå 1
Maniago 1
Manila 1
Mansfield 1
Meppel 1
Montreal 1
Nanning 1
Norwalk 1
Palermo 1
Phoenix 1
Redmond 1
Redwood City 1
Rocklin 1
Saint Louis 1
Salerno 1
Santa Clara 1
Singapore 1
Tappahannock 1
Totale 2.117
Salva come PNG Salva come JPEG
Nome #
1,3-diidro-benzimidazoloni analoghi: progettazione, sintesi e SAR di nuovi inibitori non-nucleosidici dell'RT 189
Binding mode prediction of Strand Transfer HIV-1 Integrase Inhibitors using Tn5 transposase as a plausible surrogate model for HIV-1 Integrase 58
A refined pharmacophore model and optimization of 1H-benzylindole HIV-1 integrase inhibitors 58
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors. 57
A New 3D Pharmacophore Model for HIV-1 Integrase Strand Transfer Inhibitors 56
Sviluppo di modello farmacoforico predittivo per gli NR2B antagonisti del recettore NMDA 56
Design, Synthesis and SAR of New Potent HIV-1 RT Inhibitors”. Antiviral Research 52
From 3D-pharmacophore models to synthetic route towards anti-HIV agents 51
Pharmacophore Modeling, Docking Experiments And Discovery Of New Hiv-1 NNRTIs 49
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 49
INTEGRASE STRAND TRANSFER INHIBITORS (INSTIs): SYNTHESIS AND ANTIVIRAL EFFETCS OF CHLORO-FLUORO SUBSTITUTIONS 49
Identificazione di Nuovi Inibitori Non-Nucleosidicidella Trascrittasi Inversa dell' HIV-1 Mediante Tecniche di Virtual screening 48
Discovery of HIV-1 Integrase and cellular cofactor LEDGF/p75 interaction inhibitors 48
A structure-based approach to ligand discovery for inhibition of HIV-1 IN-LEDGF/p75 interaction: a new target for anti-AIDS therapy 48
Progettazione, Sintesi e SAR di analoghi 1,3-diidro-benzimidazoloni come nuovi agenti anti-HIV 48
Design and Synthesis of NR2B Subtype-Selective Antagonist 47
Synthesis and SAR of new 1,3-dihydro-benzimidazolone analogues as non-nucleoside reverse transcriptase inhibitors (NNRTIs) 47
MOLECULAR MODELING STUDIES AND SYNTHESIS FOR THE DISCOVERY OF HIV-1 IN-LEDGF/P75 INTERACTION INHIBITORS 46
HIV-1-IN Strand-Transfer Inhibitors: phenyl ring exploration and synthesis of 1H-benzylindole derivative through fluorine substitutions 46
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 45
Novel targets for HIV therapy: small molecules blocking IN-LEDGF/p75 interaction 45
3D pharmacophore model and the synthesis of NMDA receptor subunit NR2B antagonists 44
Molecular Modeling Studies: Discovery of Novel Potent Non-Nucleoside RT Inhibitors 42
Design, synthesis and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 41
Rational design, synthesis and SAR of 1,3-dihydro-benzimidazolone analogues as new anti-HIV agents 41
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 40
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1 38
Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network 36
Nuovo modello farmacoforico per inibitori dell'Integrasi dell'HIV-1: ottimizzazione della potenza di composti a struttura 1H-benzilindolica 35
Computational Strategies for Discovering novel HIV-1 RT Inhibitors 34
A comprehensive structural overview of p38α MAPK in complex with type I inhibitors 34
IκB kinase ε targets interferon regulatory factor 1 in activated T lymphocytes 32
Pharmacophore-Based Repositioning of Approved Drugs as Novel Staphylococcus aureus NorA Efflux Pump Inhibitors 32
null 31
P38α MAPK and Type I inhibitors: Binding site analysis and use of target ensembles in virtual screening 30
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 30
Allosteric inhibition of the hepatitis C virus NS5B polymerase: In silico strategies for drug discovery and development 30
Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations 30
Structure-Based Pharmacophore Identification of New Chemical Scaffolds as Non –Nucleoside riverse Transcriptase Inhibitors 29
null 29
null 29
Development of isoquinolinone derivatives as immunoproteasome inhibitors. 29
Exploration of the binding mode of HIV-1 integrase strand transfer inhibitors through different computational approaches 28
null 28
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: A basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy 28
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase 28
Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 tat-mediated transcription activity 28
Studi Computazionali per l'Identificazione di Nuovi Inibitori Non-Nucleosidici della Trascrittasi Inversa dell'HIV-1; , 27
null 27
null 27
NCp7: targeting a multitasking protein for next-generation anti-HIV drug development part 1: covalent inhibitors 27
null 27
null 26
Pyrazolo[4,3-c ][1,2]benzothiazines 5,5-dioxide: A promising new class of staphylococcus aureus NorA efflux pump inhibitors 26
Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity 26
null 25
null 25
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes 25
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series 24
null 24
null 24
β-cyclodextrin hinders PLGA plasticization during microparticle manufacturing 24
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands 24
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity 24
Pharmacological agents targeting the cellular prion protein 24
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 24
Accounting for target flexibility and water molecules by docking to ensembles of target structures: The HCV NS5B palm site i inhibitors case study 23
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy 23
NCp7: targeting a multitask protein for next-generation anti-HIV drug development part 2. Noncovalent inhibitors and nucleic acid binders 21
A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model 20
From small to powerful: The fragments universe and its 'chem-appeal' 20
Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors 20
Tn5 transposase as a useful platform to simulate HIV-1 integrase inhibitor binding mode 19
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents 19
Tumor Targeting by Peptide-Decorated Gold Nanoparticles 19
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators 18
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 17
Re-evolution of the 2-phenylquinolines: Ligand-based design, synthesis, and biological evaluation of a potent new class of staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance 17
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside riverse transcriptase inhibitors 16
Docking studies on a new human immunodeficiency virus integrase-Mg-DNA complex: phenyl ring exploration and synthesis of 1H-benzylindole derivatives through fluorine substitutions 16
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors 16
New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site i inhibitors 16
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening 16
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors 15
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 13
Characterization of bicalutamide/cyclodextrin inclusion complexes and anticancer activity evaluation 12
Induced-Fit Docking Approach Provides Insight into the Binding Mode and Mechanism of Action of HIV-1 Integrase Inhibitors 11
Amphiphilic Cyclodextrin Nanoparticles as Delivery System for Idebenone: A Preformulation Study 11
Bicalutamide Anticancer Activity Enhancement by Formulation of Soluble Inclusion Complexes with Cyclodextrins 11
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification 11
The Versatile Nature of the 6-Aminoquinolone Scaffold: Identification of Submicromolar Hepatitis C Virus NS5B Inhibitors 11
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 10
Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication 9
l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells 9
Improvement of water solubility of non-competitive AMPA receptor antagonists by complexation with beta-cyclodextrin 9
Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs 8
Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75 7
null 4
Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn(II) complexes of bidentate and tetradentate Schiff base ligands as antileukemia agents 4
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy 3
Totale 3.002
Salva come PNG Salva come JPEG
Categoria #
all - tutte 12.280
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 12.280
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20192 0 0 0 0 0 0 0 0 0 0 0 2
2019/2020434 88 41 1 39 1 51 57 49 6 39 61 1
2020/2021394 44 0 51 11 2 42 3 86 22 41 18 74
2021/2022424 5 52 9 13 31 7 26 17 10 5 46 203
2022/20231.309 120 103 66 96 77 152 45 56 527 6 54 7
2023/2024258 41 55 23 28 35 43 7 14 6 6 0 0
Totale 3.010