PREVALENCE  OF PERTUSSIS IgG ANTIBODIES IN CHILDREN IN PALERMO, ITALY

Stroffolini, T; Giammanco, A; De Crescenzo, L; Lupo, F; Nicosia, G; Torres, G; Valenza A., R; Cascio, Antonio; Taormina, S; Nisticò, L; Chiarini, A.

The prevalence of IgG antibodies to Bordetella pertussis in a sample of 615 1-12-year-old unvaccinated children in Palermo was estimated by ELISA. The overall prevalence was 56%; it increased from 24% in one to three-year-old children to 67% in 11-12-year-old children (p less than 0.01). IgG antibody prevalence was not associated with the father's years of schooling (OR 1), nor with the family size (OR 1.3; C.I. 95% = 0.8-2.2). For children aged one the three years, serological results showed that the history of pertussis reported by parents in questionnaires gave high specificity (93.2%) and negative predictive value (85.4%). Our seroepidemiological study evidences a great exposure of children to B. pertussis in Palermo, with a high proportion of infections occurring after three years of age.

Titolo:	PREVALENCE OF PERTUSSIS IgG ANTIBODIES IN CHILDREN IN PALERMO, ITALY
Autori:	STROFFOLINI T GIAMMANCO A DE CRESCENZO L LUPO F NICOSIA G TORRES G VALENZA A. R CASCIO, Antonio TAORMINA S NISTICÒ L CHIARINI A. mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	1989
Rivista:	INFECTION
Abstract:	The prevalence of IgG antibodies to Bordetella pertussis in a sample of 615 1-12-year-old unvaccinated children in Palermo was estimated by ELISA. The overall prevalence was 56%; it increased from 24% in one to three-year-old children to 67% in 11-12-year-old children (p less than 0.01). IgG antibody prevalence was not associated with the father's years of schooling (OR 1), nor with the family size (OR 1.3; C.I. 95% = 0.8-2.2). For children aged one the three years, serological results showed that the history of pertussis reported by parents in questionnaires gave high specificity (93.2%) and negative predictive value (85.4%). Our seroepidemiological study evidences a great exposure of children to B. pertussis in Palermo, with a high proportion of infections occurring after three years of age.
Handle:	http://hdl.handle.net/11570/12953
Appare nelle tipologie:	14.a.1 Articolo su rivista

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