Microwave-assisted synthesis of benzimidazole and thiazolidinone derivatives as HIV-1 RT inhibitors

In this paper we describe the microwave-assisted synthesis of 1H,3H-thiazolo[3,4-a]benzimidazoles, 2-aryl-1-benzylbenzimidazoles and 2,3-diaryl-1,3-thiazolidin-4-ones, which achieved reductions in reaction times, higher yields, cleaner reactions than for the previously-described synthetic processes. In some cases eco-friendly solventless methodology has been used.