Population genetic data for two X-chromosomal STR loci (DXS7423 and DXS9902) were obtained by analysing a population sample (n= 60 males and 60 females) and 43 family trios (showing a probability of paternity and maternity > 99.9%) from Sicily (Southern Italy) by using PCR and PAGE followed by silver staining. Five and four different alleles of DXS7423 and DXS9902 loci were detected, respectively. The allele frequencies of both ChrX markers were in good agreement with Hardy-Weinberg equilibrium. The analysis of the family trios, based on the investigated meiotic events, showed no mutation. The observed eterozigosity of DXS7423 and DXS9902, together with other forensic parameters were determined, confirming that these markers are useful tools for parentage testing, mainly in deficiency paternity cases when the disputed child is female.
Allele distribution of two X chromosomal STR loci in a population of Sicily (Southern Italy).
ASMUNDO, Alessio;SAPIENZA, Daniela
2006-01-01
Abstract
Population genetic data for two X-chromosomal STR loci (DXS7423 and DXS9902) were obtained by analysing a population sample (n= 60 males and 60 females) and 43 family trios (showing a probability of paternity and maternity > 99.9%) from Sicily (Southern Italy) by using PCR and PAGE followed by silver staining. Five and four different alleles of DXS7423 and DXS9902 loci were detected, respectively. The allele frequencies of both ChrX markers were in good agreement with Hardy-Weinberg equilibrium. The analysis of the family trios, based on the investigated meiotic events, showed no mutation. The observed eterozigosity of DXS7423 and DXS9902, together with other forensic parameters were determined, confirming that these markers are useful tools for parentage testing, mainly in deficiency paternity cases when the disputed child is female.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
