The aim of the present study was to find possible relationships between physical exercise and oxidative stress in thoroughbreds during official races. For this purpose six healthy and trained thoroughbreds were used. Blood samples were collected from all horses at rest immediately after the race, and 30 and 180 min. after the race. The following parameters were assessed on obtained serum using the spectrophotometer method: lactate dehydrogenase, creatine kinase, reactive oxygen species, thiol antioxidant barrier and antioxidant barrier. Obtained results showed the highly significant effect of exercise on some of the studied parameters: LDH, F(3,15) = 49.85, P<0.0001; ROMs, F(3,15) = 60.71, P<0.0001; Oxy-adsorbent, F(3,15) = 393.70, P<0.0001. No statistical significant differences were observed for CK and SHP. Our results appear to indicate that during official races thoroughbreds generate free radicals, but are unable to determine a significant lyses of skeletal muscle cells.

Oxidative stress in thoroughbreds during official 1800-metre races

PICCIONE, Giuseppe;FAZIO, Francesco;GIANNETTO, CLAUDIA;ASSENZA, Anna;CAOLA, Giovanni
2007-01-01

Abstract

The aim of the present study was to find possible relationships between physical exercise and oxidative stress in thoroughbreds during official races. For this purpose six healthy and trained thoroughbreds were used. Blood samples were collected from all horses at rest immediately after the race, and 30 and 180 min. after the race. The following parameters were assessed on obtained serum using the spectrophotometer method: lactate dehydrogenase, creatine kinase, reactive oxygen species, thiol antioxidant barrier and antioxidant barrier. Obtained results showed the highly significant effect of exercise on some of the studied parameters: LDH, F(3,15) = 49.85, P<0.0001; ROMs, F(3,15) = 60.71, P<0.0001; Oxy-adsorbent, F(3,15) = 393.70, P<0.0001. No statistical significant differences were observed for CK and SHP. Our results appear to indicate that during official races thoroughbreds generate free radicals, but are unable to determine a significant lyses of skeletal muscle cells.
2007
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/1712133
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