A 76-year-old patient, since the age of 45, presented with frequent attacks often triggered by emotional stimuli and characterised by forward head drop and a fall to the ground without loss of consciousness. Clinically these episodes were misinterpreted as pseudoseizures and treated with clomipramine for more than 20 years. In spite of this chronic therapy, during the last year, the attacks presented with a daily recurrence and, moreover, after arbitrary clomipramine withdrawal, they increased in frequency until they became subcontinuous. Videopolygraphic analysis, multiple sleep latency test (MSLT) and human leukocyte antigen (HLA) association studies were suggestive of narcolepsy and the recurrent episodes, diagnosed as status cataplecticus, recovered after citalopram administration.

STATUS CATAPLECTICUS MISDIAGNOSED AS RECURRENT SYNCOPE

CALABRO', ROCCO SALVATORE;SAVICA, rodolfo;LAGANA', Angelina;MAGAUDDA, Adriana;GALLITTO, Giuseppe;LA SPINA, Pasquale;MUSOLINO, Rosa Fortunata
2007-01-01

Abstract

A 76-year-old patient, since the age of 45, presented with frequent attacks often triggered by emotional stimuli and characterised by forward head drop and a fall to the ground without loss of consciousness. Clinically these episodes were misinterpreted as pseudoseizures and treated with clomipramine for more than 20 years. In spite of this chronic therapy, during the last year, the attacks presented with a daily recurrence and, moreover, after arbitrary clomipramine withdrawal, they increased in frequency until they became subcontinuous. Videopolygraphic analysis, multiple sleep latency test (MSLT) and human leukocyte antigen (HLA) association studies were suggestive of narcolepsy and the recurrent episodes, diagnosed as status cataplecticus, recovered after citalopram administration.
2007
Inglese
STAMPA
28
6
336
338
3
Internazionale
Sì, ma tipo non specificato
clomipramine withdrawal; status cataplecticus; citalopram treatment; narcolepsy
info:eu-repo/semantics/article
CALABRÒ RS; SAVICA R; LAGANA' A; MAGAUDDA A; IMBESI D; GALLITTO G; LA SPINA P; MUSOLINO R
14.a Contributo in Rivista::14.a.1 Articolo su rivista
8
262
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/1724052
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