The synthesis of a series of 1-(alkyl- or aryl-aminocarbonylmethyl)-2-methyl- or 2-phenylindoles are described. All compounds were tested for antihypertensive activity on spontaneously hypertensive rats (SHR) and some of them showed a significant reduction of the arterial pressure.

SYNTHESIS AND ANTIHYPERTENSIVE ACTIVITY EVALUATION OF INDOLE- DERIVATIVES N-ACETAMIDO SUBSTITUTED

GRASSO, Silvana;MONFORTE, Anna Maria;MONFORTE, Pietro;ZAPPALA', Maria;MONFORTE, Maria Teresa;TROVATO, Ada
1995-01-01

Abstract

The synthesis of a series of 1-(alkyl- or aryl-aminocarbonylmethyl)-2-methyl- or 2-phenylindoles are described. All compounds were tested for antihypertensive activity on spontaneously hypertensive rats (SHR) and some of them showed a significant reduction of the arterial pressure.
1995
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/1888532
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