Severe head trauma in patients with unexplained central hypothyroidism

Central hypothyroidism can be underestimated by the paucity, tolerability, and nonspecificity of symptoms, particularly in the elderly, and by their similarity with the postconcussion syndrome. Convinced that central hypothyroidism is more frequent than believed commonly, and that head trauma could be a major cause, we have paid more attention to this possibility. We have therefore elicited a history of previous head trauma in patients with otherwise unexplained central hypothyroidism, questioning both patients and relatives.