Objective To evaluate the circadian rhythms of intraocular pressure (IOP) and tear production in dog exposed to a natural photoperiod. Animals studied We used 12 clinically healthy Beagles dog housed under natural photoperiod at indoor temperature and humidity. Procedure Intraocular pressure and Schirmer tear test (STT) I were measured every 4 h over a 48-h period in both eyes in each animal. Statistical analysis of the data was performed by one-way repeated-measures anova, Student's t-test, and single cosinor method. Results On each day, there was a highly significant effect of time on both parameters. A statistically significant difference of STT I values was observed comparing left and right eyes (P < 0.0001). Robust daily rhythms were observed for both parameters, IOP values showed diurnal acrophase (left eye: 09:33 +/- 00:50 h; right eye: 09:25 +/- 00:22 h), while STT I values showed nocturnal acrophase (left eye: 20:27 +/- 00:46 h; right eye: 20:00 +/- 00:05 h). Conclusion This study has demonstrated circadian rhythms in both IOP and STT I.

Daytime profile of the intraocular pressure and tear production in normal dog

GIANNETTO, CLAUDIA
Writing – Review & Editing
;
PICCIONE, Giuseppe
Supervision
;
GIUDICE, Elisabetta
Project Administration
2009-01-01

Abstract

Objective To evaluate the circadian rhythms of intraocular pressure (IOP) and tear production in dog exposed to a natural photoperiod. Animals studied We used 12 clinically healthy Beagles dog housed under natural photoperiod at indoor temperature and humidity. Procedure Intraocular pressure and Schirmer tear test (STT) I were measured every 4 h over a 48-h period in both eyes in each animal. Statistical analysis of the data was performed by one-way repeated-measures anova, Student's t-test, and single cosinor method. Results On each day, there was a highly significant effect of time on both parameters. A statistically significant difference of STT I values was observed comparing left and right eyes (P < 0.0001). Robust daily rhythms were observed for both parameters, IOP values showed diurnal acrophase (left eye: 09:33 +/- 00:50 h; right eye: 09:25 +/- 00:22 h), while STT I values showed nocturnal acrophase (left eye: 20:27 +/- 00:46 h; right eye: 20:00 +/- 00:05 h). Conclusion This study has demonstrated circadian rhythms in both IOP and STT I.
2009
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/1895568
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 16
  • Scopus 71
  • ???jsp.display-item.citation.isi??? 68
social impact