In this paper a macroscopic phenomenological model for the T cell mediated immune response due to a single type of antigen challenge is developed in the framework of the thermodynamic theory of fluid mixtures. Proliferation events accounting for the generation of T cell clones are considered, determining a non conservative balance for mass and momentum densities for the mixture as a whole in a way analogous to some cases in tumor modelling and growth of tissues.
A mathematical model for clonal expansion of antigen specific T cells
DOLFIN, Marina;
2010-01-01
Abstract
In this paper a macroscopic phenomenological model for the T cell mediated immune response due to a single type of antigen challenge is developed in the framework of the thermodynamic theory of fluid mixtures. Proliferation events accounting for the generation of T cell clones are considered, determining a non conservative balance for mass and momentum densities for the mixture as a whole in a way analogous to some cases in tumor modelling and growth of tissues.File in questo prodotto:
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