We have investigated the dimyristoylphosphatidylcholine system with a high concentration of butanol (two molecules per phospholipid) via X-ray diffraction, differential scanning calorimetry and density measurements. A lowering of the main transition temperature for the membrane/alcohol system has been observed. The phospholipid bilayer/alcohol system is characterised by a higher density value than the pure membrane, as determined by volumetric measurements. Analysis of diffraction patterns has shown the existence of a more packed structure due to the presence of alcohol. The area of polar head has also been estimated.
Effects of a short length alcohol on dimyristoylphosphatidylcholine system
RIFICI, SIMONA;CRUPI, CRISTINA;D'ANGELO, Giovanna;SABATINO, Giuseppe;CONTI NIBALI, VALERIA;TRIMARCHI, ANTONIO;WANDERLINGH, Ulderico
2011-01-01
Abstract
We have investigated the dimyristoylphosphatidylcholine system with a high concentration of butanol (two molecules per phospholipid) via X-ray diffraction, differential scanning calorimetry and density measurements. A lowering of the main transition temperature for the membrane/alcohol system has been observed. The phospholipid bilayer/alcohol system is characterised by a higher density value than the pure membrane, as determined by volumetric measurements. Analysis of diffraction patterns has shown the existence of a more packed structure due to the presence of alcohol. The area of polar head has also been estimated.File in questo prodotto:
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