In this works, we report some preliminary result of a systematic study performed by means of flow cytometry and specific antibodies, on the effects of the administration of 16,16-dimethyl-prostaglandin E2(di-M-PGE2), a long acting syntetic analog of PGE2, and of CY on murine lymphocytes subsets. Data show the results of a kinetic study on the recovery of spleen lymphocyte subsets, phenotypically identified by Thy1.2 antigen (T cells), Lyt-2 and L3T4 antigens (respectively CD8+ cytotoxic/suppressor and CD4+ helper/inducer T-subsets) and by the presence of surface Ig (B cells).

Modifications in spleen lymphocyte subsets after cyclophosphamide and 16,16-dimethyl prostaglandin E2 administration in mice.

MASTINO, Antonio;
1989-01-01

Abstract

In this works, we report some preliminary result of a systematic study performed by means of flow cytometry and specific antibodies, on the effects of the administration of 16,16-dimethyl-prostaglandin E2(di-M-PGE2), a long acting syntetic analog of PGE2, and of CY on murine lymphocytes subsets. Data show the results of a kinetic study on the recovery of spleen lymphocyte subsets, phenotypically identified by Thy1.2 antigen (T cells), Lyt-2 and L3T4 antigens (respectively CD8+ cytotoxic/suppressor and CD4+ helper/inducer T-subsets) and by the presence of surface Ig (B cells).
1989
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/2118221
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