Le proteine della fase acuta nel cavallo atleta. Monitoraggio in corso di allenamento

Recently, both the research and the clinical interest about monitoring acute phase proteins and response to physical exercise in the horse, have increased. In this study are reported the variations of fibrinogen (Fbg), haptoglobin (Hp) and leukocytes (WBC) in relation to training and sex in athlete horse. Seventeen 2 year-old Thoroughbred horses (10 males and 7 females; average body weight of 400 ± 16 kg) were monitored for 3 months throughout blood collection at rest, always at the same time, at the beginning of training and successively every 3 weeks. Fbg, Hp and WBC were assessed. Two-way ANOVA for repeated measures (sex and training), showed a significant effect of training on Fbg and Hp, no effect of sex was observed. Particularly, due to training, Fbg concentration increased in females (P<0.005) and Hp increased both in males and females (P<0.001). WBC showed no significant variations in relation to sex and training. These results demonstrated the influence of training on Hp concentration, which confirms itself as moderate APP and shows an adaptation to training, which can give rise to interesting speculations on the control system of the inflammatory response in athlete horse.