There are two phases following head trauma: primary and secondary injury. Primary injury (concussion, contusion, laceration) refers to pathologic changes that take place at the time when injury occurs. Secondary injury refers to a variety of pathologic processes which develop after the primary insult, resulting in progression and extension of cerebral damage. Hypotension and cerebral ischemia are both factors that have a significant impact on the pathogenesis of secondary injury. They induce autolysis of brain tissue and intracranial hypertension which can be potentially fatal. Treatment should focus on limiting the development of secondary injury by restoring of cerebral perfusion and oxygenation and reducing cerebral edema. The prognosis depends on: severity of primary damage, location of injury and access to immediate managment

Il trauma cranico. Prima parte: fisiopatologia e valutazione del paziente

MASUCCI, Marisa
2012-01-01

Abstract

There are two phases following head trauma: primary and secondary injury. Primary injury (concussion, contusion, laceration) refers to pathologic changes that take place at the time when injury occurs. Secondary injury refers to a variety of pathologic processes which develop after the primary insult, resulting in progression and extension of cerebral damage. Hypotension and cerebral ischemia are both factors that have a significant impact on the pathogenesis of secondary injury. They induce autolysis of brain tissue and intracranial hypertension which can be potentially fatal. Treatment should focus on limiting the development of secondary injury by restoring of cerebral perfusion and oxygenation and reducing cerebral edema. The prognosis depends on: severity of primary damage, location of injury and access to immediate managment
2012
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11570/2429684
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact